{"slug":"what-are-peptides-skin","verification":{"valid":true,"entries":4,"head":"72fead05208452bb0dcd433f23ed90197462684501dcd6123a403e72ccf4d3d1"},"count":4,"sources":[{"id":"s10","type":"review","url":"https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1618306/full","title":"Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials","quote":"Nineteen RCTs involving 1,341 participants were analyzed. Peptides, particularly oral formulations, significantly improved hydration and brightness, with a modest pooled effect on wrinkle reduction (MD = 0.27, p = 0.04).","summary":"2026 meta-analysis of 19 human RCTs on peptides for skin aging parameters.","claim_ids":["c1","c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:44:44.284Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"d29154ab73eb526e9d6400aaa478281ee606f7556b0944e5e6c843cd94c93bd0"},{"id":"s0","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/","title":"Regenerative and Protective Actions of the GHK-Cu Peptide in Dermal Repair","quote":"GHK-Cu applied to thigh skin for 12 weeks improved collagen production in 70% of the women treated, in contrast to 50% treated with the vitamin C cream.","summary":"Review summarizing GHK-Cu human and preclinical skin data.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:44:44.284Z","link_status":"ok","quote_status":"unverified","prev":"d29154ab73eb526e9d6400aaa478281ee606f7556b0944e5e6c843cd94c93bd0","hash":"84a4944991487b614971831e3695f5aa9671162c0db8055d52f3195e715759f2"},{"id":"s24","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10665711/","title":"Investigating the effects of Argireline in a skin serum formulation","quote":"Argireline reduced wrinkle depth by up to 30 % after four weeks of treatment without exhibiting toxicity.","summary":"Human trial on Argireline for wrinkles.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:44:44.284Z","link_status":"ok","quote_status":"unverified","prev":"84a4944991487b614971831e3695f5aa9671162c0db8055d52f3195e715759f2","hash":"de33a8b8c402152b0b5334f2c16d05592d25014febcf8ff67ca4bbb7df81d06d"},{"id":"s18","type":"pubmed","url":"https://pubs.rsc.org/en/content/articlehtml/2023/fo/d2fo02958h","title":"Oral intake of collagen peptide NS improves hydration and skin parameters","quote":"Our results show that an intake of 1650 mg per day of CPNS for 12 weeks had beneficial effects on skin health in a cohort of women aged from 30 to 60 years (n = 100).","summary":"Double-blind RCT on oral collagen peptides.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:44:44.284Z","link_status":"ok","quote_status":"unverified","prev":"de33a8b8c402152b0b5334f2c16d05592d25014febcf8ff67ca4bbb7df81d06d","hash":"72fead05208452bb0dcd433f23ed90197462684501dcd6123a403e72ccf4d3d1"}]}