{"slug":"what-are-peptides-ppis","verification":{"valid":true,"entries":6,"head":"724c62f8a35252154b778e9473f8bf44cd3d02ec14b72499b93a8538bda1d963"},"count":6,"sources":[{"id":"s8","type":"pubmed","url":"https://www.mdpi.com/2076-3921/13/9/1043","title":"Linking GERD and the Peptide Bombesin","quote":"bombesin administration... diminishing inflammatory and oxidative/nitrosative stress markers in a manner overlapping with omeprazole.","summary":"Mouse study comparing bombesin to omeprazole in GERD model.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:46:53.738Z","link_status":"http_403","quote_status":"unverified","prev":"genesis","hash":"8d846dcbc98f693be38874cf4288a20840802a993039379368d015c57e85212d"},{"id":"s18","type":"other","url":"https://patents.google.com/patent/WO2007060440A2/en","title":"WO2007060440A2 - The use of peptides in anti-ulcer therapy","quote":"The peptide may be used as a monotherapy or combined in a pharmaceutical formulation, or in a combination therapy, with a proton pump inhibitor (PPI)","summary":"Patent on ezrin peptides for ulcers, optionally with PPIs.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:46:53.738Z","link_status":"http_503","quote_status":"unverified","prev":"8d846dcbc98f693be38874cf4288a20840802a993039379368d015c57e85212d","hash":"b54136f117a664f061b14724a064e85e465ca082cf24c41a73b3c13e4d954693"},{"id":"s20","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10248387/","title":"Adverse Effects Associated with Long-Term Use of Proton Pump Inhibitors","quote":"The long-term use of PPIs has been linked to micronutrient deficiencies like hypomagnesemia, anemia, vitamin B12 deficiency, and hypocalcemia","summary":"Review of PPI nutrient deficiency risks.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:46:53.738Z","link_status":"ok","quote_status":"verified","prev":"b54136f117a664f061b14724a064e85e465ca082cf24c41a73b3c13e4d954693","hash":"fc80d71ca1a4ebcf02c35ad44d3ed8ab7991e1bf2656577214d4d56e184387c5"},{"id":"s24","type":"medical","url":"https://my.clevelandclinic.org/health/articles/proton-pump-inhibitors","title":"Proton Pump Inhibitors (PPIs): What They Are & Side Effects","quote":"PPIs may prevent your small intestine from absorbing enough magnesium or B12.","summary":"Clinical overview of PPI side effects including deficiencies.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:46:53.738Z","link_status":"ok","quote_status":"verified","prev":"fc80d71ca1a4ebcf02c35ad44d3ed8ab7991e1bf2656577214d4d56e184387c5","hash":"4018ee09492c4dbf81e80bfd6c416690cd631f6bc127aa308a85bb262c0f9670"},{"id":"s11","type":"other","url":"https://www.redfoxpeptides.is/bpc-157-for-gerd/","title":"BPC-157 for GERD: Healing Esophagus & Stopping Acid Reflux","quote":"BPC-157 targets precisely those mechanisms PPIs cannot influence.","summary":"Site summarizing BPC-157 preclinical GERD data vs PPIs.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:46:53.738Z","link_status":"ok","quote_status":"verified","prev":"4018ee09492c4dbf81e80bfd6c416690cd631f6bc127aa308a85bb262c0f9670","hash":"6bef55f3661d0fcb4cb3ad565535325ff5cfad9435b2c21def4616a4bdb0a72d"},{"id":"s34","type":"reddit","url":"https://www.reddit.com/r/GERD/comments/1i1p5h8/enough_is_enough/","title":"ENOUGH IS ENOUGH!","quote":"Recently I've been looking at oral peptides to try like BPC-157 that has apparently amazing results for healing the gut.","summary":"Reddit thread on peptides while using PPIs for GERD.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:46:53.738Z","link_status":"ok","quote_status":"unverified","prev":"6bef55f3661d0fcb4cb3ad565535325ff5cfad9435b2c21def4616a4bdb0a72d","hash":"724c62f8a35252154b778e9473f8bf44cd3d02ec14b72499b93a8538bda1d963"}]}