{"slug":"what-are-peptides-metformin","verification":{"valid":false,"broken_at":1,"reason":"hash mismatch"},"count":6,"sources":[{"id":"s5","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10236989/","title":"Association between metformin and vitamin B12 deficiency in patients with type 2 diabetes","quote":"Many studies have reported that vitamin B12 deficiency is related to the malabsorption of vitamin B12 among metformin-treated T2DM patients.","summary":"Review linking metformin to B12 malabsorption.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:55:47.197Z","link_status":"ok","quote_status":"unverified","prev":"genesis","hash":"d12aa8dffe5af7a01ee9249039142132cf8b1e53ea8f52822f845c56d7c1f59e"},{"id":"s6","type":"review","url":"https://www.wjgnet.com/1948-9358/full/v16/i7/107514.htm","title":"Metformin-induced vitamin B12 deficiency","quote":"prevalence varies widely, ranging from 5% to 40%","summary":"Details prevalence and mechanisms of B12 deficiency.","claim_ids":["c1","c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:55:47.197Z","link_status":"http_403","quote_status":"unverified","prev":"d12aa8dffe5af7a01ee9249039142132cf8b1e53ea8f52822f845c56d7c1f59e","hash":"e088615dc387aaeb2b9ea443ad710eb752c85086eee2dfad992c4aea16ca6545"},{"id":"s8","type":"review","url":"https://touchendocrinology.com/diabetes/journal-articles/metformin-use-and-vitamin-b12-deficiency-in-people-with-type-2-diabetes-what-are-the-risk-factors-a-mini-systematic-review/","title":"Metformin Use and Vitamin B12 Deficiency","quote":"Metformin inhibits complex I of the electron transport chain, which reduces adenosine triphosphate (ATP) production.","summary":"Covers mitochondrial mechanism and B12 association.","claim_ids":["c2","c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:55:47.197Z","link_status":"dead","quote_status":"unverified","prev":"e088615dc387aaeb2b9ea443ad710eb752c85086eee2dfad992c4aea16ca6545","hash":"7067fec68495ace807384f1e18ce13e592d7abb1c429614d5db6d43bec5c64c9"},{"id":"s15","type":"pubmed","url":"https://www.sciencedirect.com/science/article/abs/pii/S0026049510000168","title":"Addition of metformin to exogenous glucagon-like peptide–1","quote":"Mean AUC for plasma active GLP-1 concentrations were higher after Metformin + GLP-1","summary":"Human trial on metformin + GLP-1 combination.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:55:47.197Z","link_status":"http_400","quote_status":"unverified","prev":"7067fec68495ace807384f1e18ce13e592d7abb1c429614d5db6d43bec5c64c9","hash":"5d0ce6d00f169c90de2a4532073dee59213598822f682cc0693eae1cf0b1365b"},{"id":"s0","type":"reddit","url":"https://www.reddit.com/r/Peptides/comments/1ni172o/has_anyone_here_ever_stacked_peptides_with/","title":"Has anyone here ever stacked peptides with metformin?","quote":"I've seen people in here talk about stacking peptides together, but I'm curious if anyone has actually combined a GLP-1 like sema with metformin","summary":"Reddit discussion on stacking.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:55:47.197Z","link_status":"ok","quote_status":"unverified","prev":"5d0ce6d00f169c90de2a4532073dee59213598822f682cc0693eae1cf0b1365b","hash":"7cf62d4152398ac564c88c55958cec13b35656186d72de3fbe959a4d16aff083"},{"id":"s28","type":"reddit","url":"https://www.reddit.com/r/antidietglp1/comments/1h4ncgo/tirzepatide_and_metformin_er/","title":"Tirzepatide and Metformin ER","quote":"I had a very scary low blood sugar incident when I was riding my bike.","summary":"User experience with combination.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T21:55:47.197Z","link_status":"ok","quote_status":"unverified","prev":"7cf62d4152398ac564c88c55958cec13b35656186d72de3fbe959a4d16aff083","hash":"66c91b9e2ae8056fa6d8daad8700aab8b61c39299e2fd13e4e94c9787bd78dc7"}]}