{"slug":"what-are-peptides-chemo-neuropathy","verification":{"valid":false,"broken_at":0,"reason":"hash mismatch"},"count":5,"sources":[{"id":"s0","type":"review","url":"https://spcare.bmj.com/content/14/3/269","title":"Gabapentinoids for chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis","quote":"There is limited evidence to support the use of gabapentinoids in CIPN.","summary":"2024 meta-analysis of prevention and treatment trials.","claim_ids":["c2","c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:07:48.196Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"291231e3cb1ea8a0b880979ec03fb65288c1b53a3355b48ca594d3dba6573989"},{"id":"s8","type":"pubmed","url":"https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncr.23008","title":"Efficacy of gabapentin in the management of chemotherapy-induced peripheral neuropathy","quote":"This trial failed to demonstrate any benefit to using gabapentin to treat symptoms caused by CIPN.","summary":"2007 phase 3 RCT, N00C3 trial.","claim_ids":["c1","c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:07:48.196Z","link_status":"ok","quote_status":"unverified","prev":"291231e3cb1ea8a0b880979ec03fb65288c1b53a3355b48ca594d3dba6573989","hash":"7c9b1cd3483e9d2b611c9522912dcb2686d7f04830ce4b5e143593d7cc292b17"},{"id":"s12","type":"review","url":"https://www.cancernetwork.com/view/chemotherapy-induced-peripheral-neuropathy","title":"Chemotherapy-Induced Peripheral Neuropathy","quote":"clinicians may offer duloxetine... and should consider offering tricyclic antidepressants, gabapentin, or pregabalin... limited scientific evidence","summary":"Summary of ASCO-aligned guidance on CIPN management.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:07:48.196Z","link_status":"http_403","quote_status":"unverified","prev":"7c9b1cd3483e9d2b611c9522912dcb2686d7f04830ce4b5e143593d7cc292b17","hash":"0bada7f27154a453cf2c65cd08741e8c02b3caca5d0ef66ee8aaf62a2aaba3ef"},{"id":"s33","type":"reddit","url":"https://www.reddit.com/r/cancer/comments/1brshi9/advice_for_peripheral_neuropathy_from_chemo/","title":"Advice for peripheral neuropathy from chemo","quote":"Great I take 1200mg of gabapentin a day for post chemo neuropathy and now I am getting dementia.","summary":"Patient report of benefit and cognitive concern.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:07:48.196Z","link_status":"ok","quote_status":"unverified","prev":"0bada7f27154a453cf2c65cd08741e8c02b3caca5d0ef66ee8aaf62a2aaba3ef","hash":"0a92ebe80cac123c89599112b7f94d7a82b3488d07c5c6ed24b7dd3186638494"},{"id":"s34","type":"reddit","url":"https://www.reddit.com/r/cancer/comments/1pzkkxn/meds_for_chemo_neuropathy_proscons/","title":"Meds for chemo neuropathy? pros/cons?","quote":"Gabapentin is a pure nerve blocker that works quickly but its most common downsides are significant brain fog sedation","summary":"User discussion of mechanism and side effects.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:07:48.196Z","link_status":"ok","quote_status":"unverified","prev":"0a92ebe80cac123c89599112b7f94d7a82b3488d07c5c6ed24b7dd3186638494","hash":"0571737b6a054b16898d25325dc3eebd2c1760a5410d27fc2a4058b850790007"}]}