{"slug":"vip-semaglutide","verification":{"valid":true,"entries":5,"head":"8de7e49b9459d01eea6b103206655ae04da8c5b35b9ab4b5265e80b4579248be"},"count":5,"sources":[{"id":"s10","type":"pubmed","url":"https://www.jci.org/articles/view/17500","title":"Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension","quote":"After 3 months of daily inhalation of a total of 200 μg VIP in four single inhalations, mean pulmonary artery pressure decreased by 13 mmHg from 59 ± 8 mmHg to 46 ± 7 mmHg (P < 0.01).","summary":"Small human inhalation study in PPH patients showing hemodynamic and functional improvements.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:19:40.553Z","link_status":"ok","quote_status":"unverified","prev":"genesis","hash":"737b31dd5cc87cdc773405abadcbc53bb0b3225b2971a75c3a88d14bd0f47d80"},{"id":"s19","type":"news","url":"https://spineteamtexas.com/resources/blog/back-pain-and-glp-1-assisted-weight-loss-a-new-path-to-relief/","title":"Back Pain and GLP-1 Assisted Weight Loss","quote":"For someone who loses 30 pounds, this could mean up to 120 pounds less pressure on the spine during movement.","summary":"Explains mechanical load reduction from weight loss in context of GLP-1 agonists.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:19:40.553Z","link_status":"ok","quote_status":"verified","prev":"737b31dd5cc87cdc773405abadcbc53bb0b3225b2971a75c3a88d14bd0f47d80","hash":"f3580721923446419c2a4892dbd9fbf8375d31fcb08c1a1b8084be063a4b7b91"},{"id":"s18","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/39366019/","title":"Semaglutide exposure and its association with adverse lumbar fusion outcomes","quote":"the likelihood of undergoing additional lumbar fusion surgery within 1 year post-TLIF was significantly higher in the semaglutide-exposed group (OR 11.79, 95% CI 8.17-17.33).","summary":"Retrospective human analysis of semaglutide and spine surgery outcomes.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:19:40.553Z","link_status":"ok","quote_status":"unverified","prev":"f3580721923446419c2a4892dbd9fbf8375d31fcb08c1a1b8084be063a4b7b91","hash":"1ebf944764a4ef480dc0539f251528b6ae248c436a69f0a71c168e6dd9b181b7"},{"id":"s9","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6982157/","title":"A Clinical Approach for the Use of VIP Axis in Inflammatory and Autoimmune Diseases","quote":"On the 50th anniversary of VIP's discovery, this review presents a spectrum of potential clinical benefits applied to inflammatory and autoimmune diseases.","summary":"Review of VIP in immune modulation with preclinical emphasis.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:19:40.553Z","link_status":"ok","quote_status":"unverified","prev":"1ebf944764a4ef480dc0539f251528b6ae248c436a69f0a71c168e6dd9b181b7","hash":"946b5bff75caec35247183c181202e0dd9ad170a672e4b7fddbc4daf5dda45ac"},{"id":"s13","type":"other","url":"https://superpower.com/guides/vip","title":"VIP (Vasoactive Intestinal Peptide): Immune Modulation","quote":"VIP is not a general anti-inflammatory; it is an immune modulator that shifts cytokine balance and promotes regulatory immune cell populations.","summary":"Summary of VIP immune effects drawn from literature.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:19:40.553Z","link_status":"ok","quote_status":"unverified","prev":"946b5bff75caec35247183c181202e0dd9ad170a672e4b7fddbc4daf5dda45ac","hash":"8de7e49b9459d01eea6b103206655ae04da8c5b35b9ab4b5265e80b4579248be"}]}