{"slug":"vip-post-surgery","verification":{"valid":true,"entries":4,"head":"db9f4e0b63048666295966f206a81717bdea4334390e7be9ec4886045d3f1858"},"count":4,"sources":[{"id":"s1","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/16965837/","title":"Vasoactive intestinal peptide enhances wound healing and proliferation of human bronchial epithelial cells","quote":"The results showed that VIP accelerated the recovery of wound area of HBEC. VIP increased the migration and proliferation of HBEC, and these effects were blocked by a VPAC1 receptor antagonist.","summary":"2006 in-vitro study on human bronchial epithelial cell wound healing with VIP.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:23:38.391Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"43f55c6ed049e8e68702dcbaf0bf85385a331b8c065934443abf3fb526573e2f"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/39380035/","title":"Vasoactive intestinal peptide promotes secretory differentiation and mitigates radiation-induced intestinal injury","quote":"VIP prominently governs intestinal homeostasis by regulating epithelial progenitor cell proliferation and differentiation and promotes intestinal regeneration following acute irradiation injury.","summary":"2024 mouse study on VIP in irradiation-induced gut injury.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:23:38.391Z","link_status":"ok","quote_status":"verified","prev":"43f55c6ed049e8e68702dcbaf0bf85385a331b8c065934443abf3fb526573e2f","hash":"9b3d82ed62ca7557c812dec4274ca7c096082b464449af18c09695beb365f124"},{"id":"s3","type":"other","url":"https://esmed.org/MRA/mra/article/view/862","title":"RNA-Seq on patients with chronic inflammatory response syndrome (CIRS) treated with vasoactive intestinal peptide (VIP) shows a shift in metabolic state and innate immune functions that coincide with healing","quote":"This study surveyed 15 patients... who agreed to have their transcriptomes monitored while receiving off label, exogenous VIP nasal spray treatments.","summary":"2016 small human RNA-Seq study in CIRS patients on VIP.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:23:38.391Z","link_status":"ok","quote_status":"unverified","prev":"9b3d82ed62ca7557c812dec4274ca7c096082b464449af18c09695beb365f124","hash":"7161d88c24b7b199433db8c7789a9786889786ada15c995bebcba78a13c128a6"},{"id":"s4","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/36044317/","title":"The Use of IV Vasoactive Intestinal Peptide (Aviptadil) in Patients With Critical COVID-19 Respiratory Failure","quote":"Among the 21 patients treated with aviptadil, 19 survived to day 28, compared with 4 of the 24 individuals in the SOC group (90% vs 17%, respectively; P <.0001).","summary":"RCT of VIP analog in COVID respiratory failure (from secondary reports).","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:23:38.391Z","link_status":"ok","quote_status":"unverified","prev":"7161d88c24b7b199433db8c7789a9786889786ada15c995bebcba78a13c128a6","hash":"db9f4e0b63048666295966f206a81717bdea4334390e7be9ec4886045d3f1858"}]}