{"slug":"vip-ozempic-face","verification":{"valid":true,"entries":5,"head":"69a31808583b5a41998889e002c4847694e961afca2bd3430602b06daf0bb811"},"count":5,"sources":[{"id":"s1","type":"pubmed","url":"https://www.sciencedirect.com/science/article/pii/S0022202X15412333","title":"Vasoactive Intestinal Peptide Regulates its Receptor Expression in Normal Human Keratinocytes and in a Human Epidermal Carcinoma Cell Line","quote":"We investigated the expression of vasoactive intestinal peptide and its receptors in normal human fibroblasts and keratinocytes...","summary":"Demonstrates VIP receptor presence on human skin fibroblasts and keratinocytes.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:25:55.084Z","link_status":"http_400","quote_status":"unverified","prev":"genesis","hash":"829e4d66b92350d9c92f58871cde800a6b5ad68b6928ff05055bc596086cd497"},{"id":"s2","type":"pubmed","url":"https://www.sciencedirect.com/science/article/abs/pii/S0167011597000116","title":"Vasoactive intestinal peptide supports induced migration of human keratinocytes...","quote":"Vasoactive intestinal peptide supports induced migration of human keratinocytes and their colonization of an artificial polyurethane matrix.","summary":"Shows VIP effect on human keratinocyte migration in vitro.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:25:55.084Z","link_status":"http_400","quote_status":"unverified","prev":"829e4d66b92350d9c92f58871cde800a6b5ad68b6928ff05055bc596086cd497","hash":"305129e62cd0ff09d8f97eba0c50e61f74e2d042e0f0fcb875cd25d3653b02d8"},{"id":"s3","type":"pubmed","url":"https://journals.physiology.org/doi/full/10.1152/japplphysiol.00366.2004","title":"Mechanisms of vasoactive intestinal peptide-mediated vasodilation in human skin","quote":"Vasoactive intestinal peptide (VIP) is known to induce histamine release in human skin and to include a nitric oxide (NO)-dependent dilation...","summary":"Human skin vasodilation study with VIP.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:25:55.084Z","link_status":"http_403","quote_status":"unverified","prev":"305129e62cd0ff09d8f97eba0c50e61f74e2d042e0f0fcb875cd25d3653b02d8","hash":"2be0e04450ffc8f007123137c1f63f23d4ccc9d60e43bd4061c55944f76fb6ce"},{"id":"s4","type":"pubmed","url":"https://www.hopkinsarthritis.org/arthritis-news/vasoactive-intestinal-peptide-vip-prevents-experimental-arthritis-news-summary-from-johns-hopkins-arthritis/","title":"Vasoactive Intestinal Peptide (VIP) Prevents Experimental Arthritis","quote":"Mice treated with VIP showed delayed onset, lower incidence and decreased severity of CIA... suppression of MMP-2 gelatinase expression and activity.","summary":"Mouse CIA model results on VIP and collagen protection.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:25:55.084Z","link_status":"ok","quote_status":"unverified","prev":"2be0e04450ffc8f007123137c1f63f23d4ccc9d60e43bd4061c55944f76fb6ce","hash":"dd05280e5890e68f962fc84de06e0ed8e5962b573c4063fff96eec95bcb59ee1"},{"id":"s5","type":"news","url":"https://www.healio.com/news/dermatology/20250807/the-science-behind-ozempic-face-how-to-improve-glp1related-skin-sagging","title":"The science behind 'Ozempic face'","quote":"In one study, GLP-1s were found to act differently on adipocyte-derived stem cells... glucose uptake was significantly reduced...","summary":"Mechanistic explanation of GLP-1 effects on facial skin cells and collagen.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:25:55.084Z","link_status":"ok","quote_status":"unverified","prev":"dd05280e5890e68f962fc84de06e0ed8e5962b573c4063fff96eec95bcb59ee1","hash":"69a31808583b5a41998889e002c4847694e961afca2bd3430602b06daf0bb811"}]}