{"slug":"vip-insomnia","verification":{"valid":true,"entries":5,"head":"e46bc23d97ea71972fdbd763b1bfeaed27eba98e78b01f99bfa247f0c251515a"},"count":5,"sources":[{"id":"s1","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/3960403/","title":"Vasoactive intestinal polypeptide promotes sleep without thermoregulatory changes in the rat","quote":"VIP induced a prompt and persistent increase of sleep.","summary":"1986 rat study showing sleep promotion.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:28:45.799Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"1ed123355fb33b9ba1ec484ebaeb7bb48c1dc5735bfc4860894dbcd0ee67748e"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/6494029/","title":"Is vasoactive intestinal polypeptide (VIP) a sleep factor?","quote":"The 100 ng dose of VIP had small but significant REM enhancing properties.","summary":"1984 cat study on REM effects.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:28:45.799Z","link_status":"ok","quote_status":"unverified","prev":"1ed123355fb33b9ba1ec484ebaeb7bb48c1dc5735bfc4860894dbcd0ee67748e","hash":"d56873b0ac8cdea94729fd39958e0b7c0c7daef8282b9c4ae5a04f5a4d8e2af5"},{"id":"s3","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/3960403/","title":"Vasoactive intestinal polypeptide promotes sleep without thermoregulatory changes in the rat","quote":"Wakefulness was significantly suppressed and non-REM sleep increased.","summary":"Confirms temperature-independent sleep increase in rats.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:28:45.799Z","link_status":"ok","quote_status":"unverified","prev":"d56873b0ac8cdea94729fd39958e0b7c0c7daef8282b9c4ae5a04f5a4d8e2af5","hash":"ea972fd5dcd458816ca4928d02f898e7ff79d9aef9834430fcadb12303cacfbc"},{"id":"s4","type":"reddit","url":"https://www.reddit.com/r/UARSnew/comments/182vqgf/what_happened_to_my_sleep/","title":"What happened to my sleep?","quote":"The integrative medicine doctor I was working with prescribes VIP for 6 months to 1 year for CIRS patients.","summary":"Patient anecdote on VIP in CIRS context.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:28:45.799Z","link_status":"ok","quote_status":"unverified","prev":"ea972fd5dcd458816ca4928d02f898e7ff79d9aef9834430fcadb12303cacfbc","hash":"3ceb9511e14d7000d709eac4789e16f3920cbac138082a4d31e4fa7882f1fc0a"},{"id":"s5","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/8864295/","title":"Brain distribution of vasoactive intestinal peptide receptors","quote":"VIP has been shown to increase rapid eye movement (REM) sleep in normal and insomniac animals.","summary":"Mechanistic link to circadian and sleep regulation.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:28:45.799Z","link_status":"ok","quote_status":"unverified","prev":"3ceb9511e14d7000d709eac4789e16f3920cbac138082a4d31e4fa7882f1fc0a","hash":"e46bc23d97ea71972fdbd763b1bfeaed27eba98e78b01f99bfa247f0c251515a"}]}