{"slug":"vip-gabapentin","verification":{"valid":true,"entries":4,"head":"560971eff23a043f8f1d1de97578db1a20a0f8d6d4dad48f68480d116d483743"},"count":4,"sources":[{"id":"s5","type":"review","url":"https://www.hopkinsarthritis.org/arthritis-news/vasoactive-intestinal-peptide-vip-prevents-experimental-arthritis-news-summary-from-johns-hopkins-arthritis/","title":"Vasoactive intestinal peptide (VIP) prevents experimental arthritis","quote":"Mice treated with VIP showed delayed onset, lower incidence and decreased severity of CIA in comparison with placebo-treated arthritic mice.","summary":"Summary of mouse collagen-induced arthritis study with VIP treatment.","claim_ids":["c1","c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:31:53.539Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"4b8df224853aaf574bf8ccc9390d77e1241d85e346b0206a44cd89b6ac6d255e"},{"id":"s11","type":"clinical_trial","url":"https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2782759","title":"Effect of Vasoactive Intestinal Polypeptide on Development of Headache and Associated Symptoms","quote":"This randomized clinical trial examines whether a 2-hour infusion of vasoactive intestinal polypeptide provokes migraine attacks.","summary":"Human RCT on VIP infusion effects in volunteers.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:31:53.539Z","link_status":"http_403","quote_status":"unverified","prev":"4b8df224853aaf574bf8ccc9390d77e1241d85e346b0206a44cd89b6ac6d255e","hash":"905248284b1db39c86392540792543ce8e8e500f9a9e4f0f3461a6a21513fd0a"},{"id":"s16","type":"pubmed","url":"https://www.jci.org/articles/view/17500","title":"Vasoactive intestinal peptide as a new drug for treatment of primary pulmonary hypertension","quote":"VIP level in normal subjects (n = 45) was 42.4 ± 17.1 pg/ml. ... VIP levels in the group of PPH patients (n = 12) were at the detection threshold of the assay (i.e., 10 pg/ml).","summary":"Human measurement of VIP levels in disease vs controls.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:31:53.539Z","link_status":"ok","quote_status":"unverified","prev":"905248284b1db39c86392540792543ce8e8e500f9a9e4f0f3461a6a21513fd0a","hash":"d1572ea2abfd3790b628fc8f2e3a13b0096e4602f6e1188c16a9f3753ce6c148"},{"id":"s28","type":"other","url":"https://x.com/PharmaFactz/status/1176592633847844870","title":"Mechanism of Pregabalin / Gabapentin","quote":"both drugs act as inhibitors of α2δ subunit-containing voltage-dependent calcium channels (VDCCs).","summary":"Explanation of gabapentin/pregabalin mechanism.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:31:53.539Z","link_status":"ok","quote_status":"verified","prev":"d1572ea2abfd3790b628fc8f2e3a13b0096e4602f6e1188c16a9f3753ce6c148","hash":"560971eff23a043f8f1d1de97578db1a20a0f8d6d4dad48f68480d116d483743"}]}