{"slug":"tirzepatide-trigeminal","verification":{"valid":true,"entries":5,"head":"3d9e449c7e928059ea51d431960acc37965855c0680221ce01ab1d1096ff51cf"},"count":5,"sources":[{"id":"s1","type":"pubmed","url":"https://www.nejm.org/doi/full/10.1056/NEJMoa2206038","title":"Tirzepatide Once Weekly for the Treatment of Obesity","quote":"The present trial, SURMOUNT-1, evaluated the efficacy and safety of tirzepatide in adults with obesity or overweight who did not have diabetes.","summary":"Phase 3 trial showing substantial weight loss with tirzepatide.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:36:58.640Z","link_status":"http_403","quote_status":"unverified","prev":"genesis","hash":"578bf6a7cb2b0b92cbe09dc9f30f95c5708510cb0cc786d5b57a73448b72f249"},{"id":"s2","type":"other","url":"https://www.cureus.com/articles/369771-allodynia-and-dysesthesia-associated-with-semaglutide-and-tirzepatide","title":"Allodynia and Dysesthesia Associated With Semaglutide and Tirzepatide","quote":"The symptom of allodynia is commonly associated with conditions such as fibromyalgia, trigeminal neuralgia, diabetic peripheral neuropathy, and ...","summary":"Case report noting rare sensory symptoms but no TN-specific trials.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:36:58.640Z","link_status":"ok","quote_status":"unverified","prev":"578bf6a7cb2b0b92cbe09dc9f30f95c5708510cb0cc786d5b57a73448b72f249","hash":"197c7adb295304afe06faaf5386935122eaa7781e65d4f30f1c5788b50653e03"},{"id":"s3","type":"reddit","url":"https://www.reddit.com/r/TrigeminalNeuralgia/comments/1i0lrqd/coincidence/","title":"Coincidence??","quote":"I was on tirzepatide for about 6 months. I stopped using the tirzepatide and the pain came back.","summary":"Patient anecdote of pain resolution during tirzepatide use.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:36:58.640Z","link_status":"ok","quote_status":"unverified","prev":"197c7adb295304afe06faaf5386935122eaa7781e65d4f30f1c5788b50653e03","hash":"84332801fc4ca70e587ff21d091caa464a86d8f48d5d808d9533f75125d11aea"},{"id":"s4","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12594042/","title":"Allodynia and Dysesthesia Associated With Semaglutide and Tirzepatide","quote":"The tirzepatide was stopped, and the pain completely resolved.","summary":"Documents temporal association with sensory symptoms.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:36:58.640Z","link_status":"ok","quote_status":"verified","prev":"84332801fc4ca70e587ff21d091caa464a86d8f48d5d808d9533f75125d11aea","hash":"bddd3cfc19817a980044a95bf58c606cf6c83a8fa51f62ddb3e09d6a10630f1c"},{"id":"s5","type":"review","url":"https://www.mayoclinic.org/drugs-supplements/tirzepatide-subcutaneous-route/description/drg-20534045","title":"Tirzepatide (subcutaneous route)","quote":"Tirzepatide injection is also used to help lose weight and keep the weight off in patients with obesity caused by certain conditions.","summary":"Official description confirming weight-loss mechanism.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:36:58.640Z","link_status":"http_403","quote_status":"unverified","prev":"bddd3cfc19817a980044a95bf58c606cf6c83a8fa51f62ddb3e09d6a10630f1c","hash":"3d9e449c7e928059ea51d431960acc37965855c0680221ce01ab1d1096ff51cf"}]}