{"slug":"tirzepatide-tendon","verification":{"valid":true,"entries":3,"head":"8ea0fed677ee6fd5682b9207571f69d384ce78ef28f02ba5a615e845b73958a8"},"count":3,"sources":[{"id":"s1","type":"pubmed","url":"https://acrabstracts.org/abstract/impact-of-tirzepatide-on-musculoskeletal-pain-and-high-risk-analgesic-use-among-non-diabetic-patients-with-overweight-or-obesity-a-propensity-score-matched-active-comparator-new-user-study/","title":"Impact of Tirzepatide on Musculoskeletal Pain...","quote":"Tirzepatide users were significantly more likely to achieve a normal BMI... lower risk of joint pain with HR 0.91... knee pain (HR 0.84)... NSAID (HR 0.88) and opioid prescriptions (HR 0.86).","summary":"Propensity-matched study showing reduced joint pain and analgesic use with tirzepatide vs phentermine.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:37:59.382Z","link_status":"ok","quote_status":"unverified","prev":"genesis","hash":"df59b4b4ca4d875cd6589a35a5e1c98b6d0b1d8a273d734330200e6fbbb9c10a"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/41032183/","title":"Anti-inflammatory effects of tirzepatide: a systematic review...","quote":"tirzepatide reduced hsCRP (mean difference [MD]: -32.9...) and IL-6 (MD: -17.8...)","summary":"Meta-analysis confirming reductions in inflammatory markers with tirzepatide.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:37:59.382Z","link_status":"ok","quote_status":"unverified","prev":"df59b4b4ca4d875cd6589a35a5e1c98b6d0b1d8a273d734330200e6fbbb9c10a","hash":"39bbb822ba5025354e0fd3657234d04471539290b1fe0d637808dcf59535c978"},{"id":"s3","type":"other","url":"https://nwregen.com/articles/beyond-the-scale-the-surprising-benefits-of-tirzepatide-for-joint-and-metabolic-health/","title":"The Benefits of Tirzepatide for Joint and Metabolic Health","quote":"For every pound of excess weight, the joints can experience up to four additional pounds of pressure with each step.","summary":"Article citing standard 4:1 load reduction ratio for weight-bearing structures.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:37:59.382Z","link_status":"ok","quote_status":"verified","prev":"39bbb822ba5025354e0fd3657234d04471539290b1fe0d637808dcf59535c978","hash":"8ea0fed677ee6fd5682b9207571f69d384ce78ef28f02ba5a615e845b73958a8"}]}