{"slug":"tirzepatide-insomnia","verification":{"valid":true,"entries":4,"head":"39b565d0569cbc34459a823041340d6a1a6e501ff1ec24d6008164da8e59e91a"},"count":4,"sources":[{"id":"web:20","type":"pubmed","url":"https://www.nejm.org/doi/abs/10.1056/NEJMoa2404881","title":"Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity","quote":"Among persons with moderate-to-severe obstructive sleep apnea and obesity, tirzepatide reduced the AHI, body weight, hypoxic burden...","summary":"Phase 3 RCT results showing AHI reduction and secondary sleep outcomes.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:45:03.157Z","link_status":"http_403","quote_status":"unverified","prev":"genesis","hash":"a8f93edab73c3035e662e7f06ad614af301baedaae75873e9a45e9bff8b1c3dd"},{"id":"web:39","type":"news","url":"https://www.fda.gov/news-events/press-announcements/fda-approves-first-medication-obstructive-sleep-apnea","title":"FDA Approves First Medication for Obstructive Sleep Apnea","quote":"Today, the U.S. Food and Drug Administration approved Zepbound (tirzepatide) for the treatment of moderate to severe obstructive sleep apnea...","summary":"FDA approval announcement for OSA indication.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:45:03.157Z","link_status":"ok","quote_status":"unverified","prev":"a8f93edab73c3035e662e7f06ad614af301baedaae75873e9a45e9bff8b1c3dd","hash":"56988b1622dbb8ef148b0de52aea0ad789976b6e040546a21aec5fd705ba6fda"},{"id":"web:10","type":"reddit","url":"https://www.reddit.com/r/tirzepatidecompound/comments/1gxavj2/tirzepatide_compound_insomnia/","title":"Tirzepatide compound INSOMNIA?","quote":"I am on week 4 of 15units and have been experiencing really bad insomnia . Especially 2-4 days after my shot.","summary":"User report of insomnia timing with tirzepatide dosing.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:45:03.157Z","link_status":"ok","quote_status":"unverified","prev":"56988b1622dbb8ef148b0de52aea0ad789976b6e040546a21aec5fd705ba6fda","hash":"d0e39084f38cac3418767acd1cd5b1015d4d54ea36a0882a6a184cf4002d4979"},{"id":"web:2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/41135142/","title":"Tirzepatide for sleep-disordered breathing in SURMOUNT-OSA","quote":"The magnitude of changes in AHI and SASHB were associated with achieved weight reduction in both studies.","summary":"Post-hoc analysis linking weight loss to OSA improvement.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:45:03.157Z","link_status":"ok","quote_status":"verified","prev":"d0e39084f38cac3418767acd1cd5b1015d4d54ea36a0882a6a184cf4002d4979","hash":"39b565d0569cbc34459a823041340d6a1a6e501ff1ec24d6008164da8e59e91a"}]}