{"slug":"tirzepatide-herniated-disc","verification":{"valid":true,"entries":5,"head":"82ccc4668d9d0b47cba6c7e7506d87b3cc0265324d5797c6063bf969ddaf2631"},"count":5,"sources":[{"id":"s1","type":"pubmed","url":"https://www.nejm.org/doi/full/10.1056/NEJMoa2206038","title":"Tirzepatide Once Weekly for the Treatment of Obesity","quote":"The mean percentage change in weight at week 72 was −15.0% ... with 5-mg ... −19.5% ... with 10-mg ... −20.9% ... with 15-mg doses and −3.1% ... with placebo","summary":"Phase 3 RCT showing substantial sustained weight loss in humans with obesity.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:47:08.967Z","link_status":"http_403","quote_status":"unverified","prev":"genesis","hash":"93dd82cb9ffe7ee4c8f436086a1eecc22ca3ac94ace81accb3b36e171308f5a4"},{"id":"s2","type":"medical","url":"https://www.spine.md/insights/impact-weight-spinal-health","title":"The Impact of Weight on Spinal Health","quote":"each kilogram of weight loss decreasing compressive force on lumbar vertebrae by approximately 4 kilograms","summary":"Spine-health resource citing the 4:1 load-reduction relationship.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:47:08.967Z","link_status":"ok","quote_status":"verified","prev":"93dd82cb9ffe7ee4c8f436086a1eecc22ca3ac94ace81accb3b36e171308f5a4","hash":"84106cbd39d2955121e166cda731cd4171f791c20b07cfbd3d0d19ca7e9a745d"},{"id":"s3","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/31266512/","title":"Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats","quote":"BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats","summary":"Preclinical rat study on spinal injury recovery.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:47:08.967Z","link_status":"ok","quote_status":"verified","prev":"84106cbd39d2955121e166cda731cd4171f791c20b07cfbd3d0d19ca7e9a745d","hash":"a29ddf93be40e2496520151f8be05490c1914ba76535fedf67c9690bc530ed31"},{"id":"s4","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5741312/","title":"Targeting the innate repair receptor to treat neuropathy","quote":"In humans, ARA290 has been evaluated in patients with small fiber neuropathy associated with sarcoidosis or type 2 diabetes (T2D) mellitus. In patients with sarcoidosis, ARA290 significantly improved neuropathic and autonomic symptoms...","summary":"Human data on ARA-290 for small-fiber neuropathy symptoms and nerve fiber density.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:47:08.967Z","link_status":"ok","quote_status":"verified","prev":"a29ddf93be40e2496520151f8be05490c1914ba76535fedf67c9690bc530ed31","hash":"87604d7a59bc19d183f2e05aa1388e7048fea34146faab039e80a42297e88a8f"},{"id":"s5","type":"medical","url":"https://friscorehab.com/can-bpc-157-heal-a-herniated-disc-what-patients-with-back-pain-should-know/","title":"Can BPC-157 Heal a Herniated Disc?","quote":"there is currently no strong clinical evidence showing BPC-157 can repair or reverse a herniated disc in humans","summary":"Summary of evidence gaps for BPC-157 and related peptides in disc conditions.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:47:08.967Z","link_status":"ok","quote_status":"unverified","prev":"87604d7a59bc19d183f2e05aa1388e7048fea34146faab039e80a42297e88a8f","hash":"82ccc4668d9d0b47cba6c7e7506d87b3cc0265324d5797c6063bf969ddaf2631"}]}