{"slug":"tirzepatide-corticosteroids","verification":{"valid":true,"entries":4,"head":"823d41030f93070b2cb65a17e08b920b41f67e72faeeb6fe51b703c317ccee89"},"count":4,"sources":[{"id":"s1","type":"pubmed","url":"https://www.nejm.org/doi/full/10.1056/NEJMoa2206038","title":"Tirzepatide Once Weekly for the Treatment of Obesity","quote":"mean percentage change in weight at week 72 was −15.0% ... −19.5% ... −20.9% ... with placebo","summary":"Phase 3 trial results on weight loss percentages.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:50:08.390Z","link_status":"http_403","quote_status":"unverified","prev":"genesis","hash":"d87fb04a525e87402c98b1a5a9b363d7e6e3a962a6bcf0921633b9bae01af958"},{"id":"s2","type":"other","url":"https://spineteamtexas.com/resources/blog/back-pain-and-glp-1-assisted-weight-loss-a-new-path-to-relief/","title":"Back Pain and GLP-1 Assisted Weight Loss","quote":"For every extra pound a person carries, the force exerted on the lower back increases significantly—some estimates suggest up to four times the amount of pressure","summary":"Discusses mechanical load multiplier for spine.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:50:08.390Z","link_status":"ok","quote_status":"verified","prev":"d87fb04a525e87402c98b1a5a9b363d7e6e3a962a6bcf0921633b9bae01af958","hash":"4be245507a90d091f761c74bc81eff63396c2bb3fcbee6beb696175b0236000c"},{"id":"s3","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5815012/","title":"Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis","quote":"injections with triamcinolone resulted in significantly greater cartilage volume loss than did saline","summary":"Human RCT on repeated corticosteroid cartilage effects.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:50:08.390Z","link_status":"ok","quote_status":"unverified","prev":"4be245507a90d091f761c74bc81eff63396c2bb3fcbee6beb696175b0236000c","hash":"b73cc7f694b43f4f7f1ba5ab56dc1126ae5f66cadb23e854337b1ab13444201f"},{"id":"s4","type":"other","url":"https://www.drugs.com/drug-interactions/prednisone-with-tirzepatide-1936-0-4363-0.html","title":"Prednisone + Tirzepatide Interactions","quote":"PredniSONE may interfere with blood glucose control and reduce the effectiveness of tirzepatide","summary":"Drug interaction summary.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:50:08.390Z","link_status":"http_403","quote_status":"unverified","prev":"b73cc7f694b43f4f7f1ba5ab56dc1126ae5f66cadb23e854337b1ab13444201f","hash":"823d41030f93070b2cb65a17e08b920b41f67e72faeeb6fe51b703c317ccee89"}]}