{"slug":"tirzepatide-chemo-neuropathy","verification":{"valid":true,"entries":5,"head":"9677b924d38b52377eb9f85c4e6551b1d6c7822a57fd9a1f3a8c1acedbe9a6be"},"count":5,"sources":[{"id":"s2","type":"other","url":"https://connect.mayoclinic.org/discussion/drug-induced-pn-due-to-tirzepatide/","title":"Drug-induced PN due to tirzepatide","quote":"This process revealed a clear temporal association between the worsening of neuropathic symptoms and the administration of tirzepatide.","summary":"Patient case on Mayo forum linking tirzepatide to PN worsening.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:50:57.377Z","link_status":"http_403","quote_status":"unverified","prev":"genesis","hash":"8fbdb9d4b96d7eea8342d89d845d6b73022770383b76ff47f26c65ee7e9907ed"},{"id":"s4","type":"pubmed","url":"https://www.frontiersin.org/journals/toxicology/articles/10.3389/ftox.2026.1752511/full","title":"The lack of efficacy of tirzepatide in mitigating cisplatin-induced neurotoxicity and cognitive impairment in rats","quote":"This study aimed to evaluate the efficacy of tirzepatide in mitigating the neuropathy effects induced by cisplatin therapy.","summary":"2026 rat study showing no neuroprotective effect in cisplatin model.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:50:57.377Z","link_status":"ok","quote_status":"verified","prev":"8fbdb9d4b96d7eea8342d89d845d6b73022770383b76ff47f26c65ee7e9907ed","hash":"a80d73fe99fd7cd0c11f4a7aab071164806a4037418a717a1e19f9868ff94152"},{"id":"s10","type":"news","url":"https://www.medscape.com/viewarticle/reduced-risk-peripheral-neuropathy-tied-diabetes-medication-2024a1000buh","title":"Reduced Risk for Peripheral Neuropathy Tied to Diabetes Medication","quote":"Those taking tirzepatide had a significantly reduced risk for DPN over 2 years compared with their counterparts who were on insulin or other diabetes medications.","summary":"Database analysis of tirzepatide and DPN risk reduction.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:50:57.377Z","link_status":"ok","quote_status":"unverified","prev":"a80d73fe99fd7cd0c11f4a7aab071164806a4037418a717a1e19f9868ff94152","hash":"a349a04280d17c0b471b87a2ddf13ec9625fdb56827c5dfa35384b77339845be"},{"id":"s18","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/40391981/","title":"Common peroneal neuropathy following significant weight loss induced by tirzepatide therapy","quote":"Common peroneal neuropathy following significant weight loss induced by tirzepatide therapy.","summary":"Case linking tirzepatide weight loss to neuropathy.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:50:57.377Z","link_status":"ok","quote_status":"unverified","prev":"a349a04280d17c0b471b87a2ddf13ec9625fdb56827c5dfa35384b77339845be","hash":"b5102fa0c820caa3209208d7c089910346496c1600a720919f5c97b83942d1c7"},{"id":"s19","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/39051436/","title":"The Tirzepatide Drop: Beware of Slimmer's Paralysis","quote":"This case series explores the association between tirzepatide-assisted weight loss and the development of foot drop due to peroneal nerve neuropathy.","summary":"Case series on weight-loss associated peroneal neuropathy.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:50:57.377Z","link_status":"ok","quote_status":"unverified","prev":"b5102fa0c820caa3209208d7c089910346496c1600a720919f5c97b83942d1c7","hash":"9677b924d38b52377eb9f85c4e6551b1d6c7822a57fd9a1f3a8c1acedbe9a6be"}]}