{"slug":"thymosin-alpha-1-semaglutide","verification":{"valid":true,"entries":6,"head":"239d975b988c130ae6d477769d17ada2b78855a1e95e5709de40429f23b39338"},"count":6,"sources":[{"id":"s1","type":"review","url":"https://pubmed.ncbi.nlm.nih.gov/38308608/","title":"Comprehensive Review of the Safety and Efficacy of Thymosin Alpha 1","quote":"This study aims to assess the safety and efficacy of Thymosin Alpha 1 (Tα1) through a comprehensive narrative review of clinical studies involving over 11 000 human subjects in more than 30 trials.","summary":"2024 narrative review of Tα1 clinical studies.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:57:01.933Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"6a809ebd4ac8fbff475ef9a072664bf0eee1629c1b20d67bfa94b3674ef887b6"},{"id":"s2","type":"clinical_trial","url":"https://www.bmj.com/content/388/bmj-2024-082583","title":"The efficacy and safety of thymosin α1 for sepsis (TESTS)","quote":"This trial found no clear evidence to suggest that thymosin α1 decreases 28 day all cause mortality in adults with sepsis.","summary":"2025 RCT results on sepsis mortality.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:57:01.933Z","link_status":"http_403","quote_status":"unverified","prev":"6a809ebd4ac8fbff475ef9a072664bf0eee1629c1b20d67bfa94b3674ef887b6","hash":"ee562114f22d4e9a86240c2d932f02ce9c1fd5b02ffdd745b580bcc505696838"},{"id":"s3","type":"review","url":"https://pubmed.ncbi.nlm.nih.gov/27450734/","title":"Immune Modulation with Thymosin Alpha 1 Treatment","quote":"Ta1 acts through Toll-like receptors in both myeloid and plasmacytoid dendritic cells, leading to activation and stimulation of signaling pathways and initiation of production of immune-related cytokines.","summary":"Mechanism review of Tα1.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:57:01.933Z","link_status":"ok","quote_status":"verified","prev":"ee562114f22d4e9a86240c2d932f02ce9c1fd5b02ffdd745b580bcc505696838","hash":"84ef622b3ea3b35373387728970cf58cab70fa5f16d700d383923774de7612cd"},{"id":"s4","type":"other","url":"https://spineteamtexas.com/resources/blog/back-pain-and-glp-1-assisted-weight-loss-a-new-path-to-relief/","title":"Back Pain and GLP-1 Assisted Weight Loss","quote":"For someone who loses 30 pounds, this could mean up to 120 pounds less pressure on the spine during movement.","summary":"Biomechanical load reduction example.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:57:01.933Z","link_status":"ok","quote_status":"verified","prev":"84ef622b3ea3b35373387728970cf58cab70fa5f16d700d383923774de7612cd","hash":"e520fa8fd6a9b79e89a96497048e838985ac47d98133bea4eb028d82492cde2c"},{"id":"s5","type":"other","url":"https://formblends.com/articles/peptide-hub/thymosin-alpha-1-with-glp-1-interaction-safety","title":"Thymosin Alpha-1 with Glp-1: Interaction Safety","quote":"There are no known direct pharmacological interactions between Thymosin Alpha-1 and GLP-1 agonists.","summary":"Absence of combo trial data noted.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:57:01.933Z","link_status":"ok","quote_status":"verified","prev":"e520fa8fd6a9b79e89a96497048e838985ac47d98133bea4eb028d82492cde2c","hash":"8877536bd840f723805d3fa56b80a47b77a8ea9c0b582cb305b29a106f18e620"},{"id":"s6","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/39366019/","title":"Semaglutide exposure and its association with adverse spine surgery outcomes","quote":"Semaglutide exposure appears to be associated with a higher likelihood of additional lumbar fusion surgeries within 1 year post-TLIF.","summary":"Observational spine surgery association.","claim_ids":["c6"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T22:57:01.933Z","link_status":"ok","quote_status":"unverified","prev":"8877536bd840f723805d3fa56b80a47b77a8ea9c0b582cb305b29a106f18e620","hash":"239d975b988c130ae6d477769d17ada2b78855a1e95e5709de40429f23b39338"}]}