{"slug":"thymosin-alpha-1-corticosteroids","verification":{"valid":true,"entries":5,"head":"379abd576c46cfbc9fe892195c4211d70dd90b5649f52a516e56e99800df299a"},"count":5,"sources":[{"id":"s10","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/38308608/","title":"Comprehensive Review of the Safety and Efficacy of Thymosin Alpha 1 in Human Clinical Trials","quote":"comprehensive narrative review of clinical studies involving over 11 000 human subjects in more than 30 trials","summary":"Large safety review of Tα1.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:06:59.404Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"9b9fce57d05fcd0814307135433d32f6a20bbc16bb2eb6224f16d0050b74023a"},{"id":"s13","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/38308608/","title":"The efficacy and safety of thymosin α1 for sepsis (TESTS)","quote":"This trial found no clear evidence to suggest that thymosin α1 decreases 28 day all cause mortality in adults with sepsis.","summary":"Negative RCT for sepsis mortality.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:06:59.404Z","link_status":"ok","quote_status":"unverified","prev":"9b9fce57d05fcd0814307135433d32f6a20bbc16bb2eb6224f16d0050b74023a","hash":"7e36f07d1cdf14aee166f89d2d02b89257ac4854894926feee4d17447d9fe471"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/9147362/","title":"Thymosin alpha 1 antagonizes dexamethasone and CD3-induced apoptosis","quote":"Thymosin alpha 1 (T alpha 1)... is a dose and time dependent antagonist of dexamethasone (DEX) and CD3 induced DNA fragmentation","summary":"Preclinical antagonism of DEX apoptosis.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:06:59.404Z","link_status":"ok","quote_status":"unverified","prev":"7e36f07d1cdf14aee166f89d2d02b89257ac4854894926feee4d17447d9fe471","hash":"52f7b3fe810d29a1e02baee1c7d0d10c1c762959aeea1ee1ecacdd4ba0cde8c2"},{"id":"s33","type":"pubmed","url":"https://www.nature.com/articles/s41598-018-30956-y","title":"Thymosin Alpha1-Fc Modulates the Immune System and Prevents Tumor Progression","quote":"Tα1-Fc restored immune system of immunocompromised mice induced by hydrocortisone","summary":"Mouse model of steroid immunosuppression reversed.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:06:59.404Z","link_status":"ok","quote_status":"verified","prev":"52f7b3fe810d29a1e02baee1c7d0d10c1c762959aeea1ee1ecacdd4ba0cde8c2","hash":"a345d9dec61e21d68104530381d4470cbd66c73582f2dae26d911fd45858f3ac"},{"id":"s15","type":"other","url":"https://www.innerbody.com/thymosin-alpha-1-peptide","title":"Thymosin Alpha-1 Peptide: Benefits and Safety","quote":"patients who were on disease-modifying antirheumatic drugs (DMARDs) plus steroids had “significantly higher” TA-1 levels than those on other treatments","summary":"Observational serum levels in autoimmune patients on steroids.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:06:59.404Z","link_status":"ok","quote_status":"verified","prev":"a345d9dec61e21d68104530381d4470cbd66c73582f2dae26d911fd45858f3ac","hash":"379abd576c46cfbc9fe892195c4211d70dd90b5649f52a516e56e99800df299a"}]}