{"slug":"thymosin-alpha-1-cognition","verification":{"valid":true,"entries":5,"head":"c8d12ddceb8c65d07afb5d66dc0389c3455e208f3da198d0ee896bc19a18bfd7"},"count":5,"sources":[{"id":"s1","type":"pubmed","url":"https://www.sciencedirect.com/science/article/abs/pii/S0006899320303966","title":"Improvement in cognitive dysfunction following blast induced traumatic brain injury by thymosin α1 in rats","quote":"Tα1 treatment markedly improved cognitive dysfunction by decreasing the escape latency in the acquisition phase, and increasing the crossing numbers in the probe phase of MWM test.","summary":"Rat TBI model showing cognitive improvement with TA1 linked to tau changes.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:07:58.229Z","link_status":"http_403","quote_status":"unverified","prev":"genesis","hash":"7b4521148a5bfaeee2c4efeef741c72798afd9e8df34d50b09a423afa3609073"},{"id":"s2","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5725380/","title":"Immunopotentiator Thymosin Alpha-1 Promotes Neurogenesis and Cognition in the Developing Mouse via a Systemic Th1 Bias","quote":"These findings suggest that peripheral Ta1 contributes to neurogenesis and cognition probably through a systemic Th1 bias, as well as neuroprotection against inflammation.","summary":"Mouse study connecting TA1 to neurogenesis and cognition.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:07:58.229Z","link_status":"ok","quote_status":"unverified","prev":"7b4521148a5bfaeee2c4efeef741c72798afd9e8df34d50b09a423afa3609073","hash":"7232a0636df99b61afe1ee32640377de3d076896acafc596a011c5f55ce867a6"},{"id":"s3","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12692621/","title":"Aging and Thymosin Alpha-1","quote":"Tα1 stimulates neurogenesis and improves cognitive functions [97], which makes it a promising candidate for the treatment of age-related cognitive impairment.","summary":"Review noting potential for age-related cognition in models.","claim_ids":[],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:07:58.229Z","link_status":"ok","quote_status":"unverified","prev":"7232a0636df99b61afe1ee32640377de3d076896acafc596a011c5f55ce867a6","hash":"00c37380c9c123a132d1d9e3cee75d64b258aef5a0e2dd2a9d6040b376c3f12e"},{"id":"s4","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11017181/","title":"Thymosin α1 combined with XELOX improves immune function and quality of life in CRC patients","quote":"the cognitive function level increased from 66.63 ± 6.97 to 78.43 ± 6.50","summary":"Human QoL data showing cognitive score gains with TA1 in cancer setting.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:07:58.229Z","link_status":"ok","quote_status":"verified","prev":"00c37380c9c123a132d1d9e3cee75d64b258aef5a0e2dd2a9d6040b376c3f12e","hash":"f4cd8aa9ab3e74a65f615874d877e047d5a1e8d06f0f0fd918902a8d87c35d99"},{"id":"s5","type":"reddit","url":"https://www.reddit.com/r/covidlonghaulers/comments/1r5ekd8/5_years_long_covid_thymosin_alpha_1_peptide_wow/","title":"5 Years Long Covid - Thymosin Alpha 1 Peptide - WOW!","quote":"No fatigue no brain fog, waking up early as my energy is back.","summary":"User reports of brain fog reduction with TA1 in long COVID context.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:07:58.229Z","link_status":"ok","quote_status":"unverified","prev":"f4cd8aa9ab3e74a65f615874d877e047d5a1e8d06f0f0fd918902a8d87c35d99","hash":"c8d12ddceb8c65d07afb5d66dc0389c3455e208f3da198d0ee896bc19a18bfd7"}]}