{"slug":"tesamorelin-benzodiazepines","verification":{"valid":true,"entries":5,"head":"2868fe981bf1c4f956e7fcffb4629566c948e067e009959d6b82d1b4f548b39a"},"count":5,"sources":[{"id":"s0","type":"medical","url":"https://www.mayoclinic.org/drugs-supplements/tesamorelin-subcutaneous-route/description/drg-20074632","title":"Tesamorelin (subcutaneous route) - Description","quote":"It is used to reduce excess fat (lipodystrophy) in the stomach area in patients with human immunodeficiency virus (HIV) infection.","summary":"Official description of tesamorelin's approved use for HIV lipodystrophy.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:26:59.311Z","link_status":"http_403","quote_status":"unverified","prev":"genesis","hash":"6a6900378aedd09e7e8f49e66c40a8b6472d9e064a678f72bfa455f36614e803"},{"id":"s1","type":"medical","url":"https://medlineplus.gov/druginfo/meds/a611035.html","title":"Tesamorelin Injection: MedlinePlus Drug Information","quote":"Tesamorelin injection is used to decrease the amount of extra fat in the stomach area in adults with human immunodeficiency virus (HIV) who have lipodystrophy.","summary":"Confirms primary indication for visceral fat reduction.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:26:59.311Z","link_status":"ok","quote_status":"unverified","prev":"6a6900378aedd09e7e8f49e66c40a8b6472d9e064a678f72bfa455f36614e803","hash":"f9a0e5e055f91a83059ef2a0cd9f6778e6be84946e3bc3c501c821522a3aeb21"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/17086939/","title":"tesamorelin, a synthetic human growth hormone releasing factor analog","quote":"Theratechnologies, under license from Valeant, is developing tesamorelin as a potential vaccine adjuvant and for the potential treatment of wasting, hip fracture recovery, immune disorders, HIV-related lipodystrophy, sleep maintenance insomnia and mild cognitive impairment.","summary":"Early pipeline mention of sleep insomnia exploration.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:26:59.311Z","link_status":"ok","quote_status":"verified","prev":"f9a0e5e055f91a83059ef2a0cd9f6778e6be84946e3bc3c501c821522a3aeb21","hash":"a5aa8ddd05536d9449a5b134653b452244baa2792a994e7074a48d3acbe22194"},{"id":"s6","type":"medical","url":"https://go.drugbank.com/drugs/DB08869","title":"Tesamorelin: Uses, Interactions, Mechanism of Action","quote":"Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy.","summary":"Mechanism and indication details.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:26:59.311Z","link_status":"http_403","quote_status":"unverified","prev":"a5aa8ddd05536d9449a5b134653b452244baa2792a994e7074a48d3acbe22194","hash":"36c313e8956fc2c6b924d13562b8ae5489a17e74598ab14619ff22c4681de5b2"},{"id":"s17","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4014019/","title":"Benzodiazepine dependence and its treatment with low dose flumazenil","quote":"The benzodiazepines allosterically enhance the inhibitory actions of GABA by binding to the modulatory site located between the α1, α2, α3 or α5 and γ subunits.","summary":"Describes GABA mechanism of benzodiazepines.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:26:59.311Z","link_status":"ok","quote_status":"unverified","prev":"36c313e8956fc2c6b924d13562b8ae5489a17e74598ab14619ff22c4681de5b2","hash":"2868fe981bf1c4f956e7fcffb4629566c948e067e009959d6b82d1b4f548b39a"}]}