{"slug":"tb-500-skin","verification":{"valid":true,"entries":5,"head":"7a1670c9ef58e3ce8d0471d691306eb95a756a8fd397cb869de84515154d391d"},"count":5,"sources":[{"id":"s0","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8228050/","title":"Utilizing Developmentally Essential Secreted Peptides Such ...","quote":"In dermal phase II trials, TB4 promoted wound healing by accelerating the rate of repair. Patients with pressure ulcers, stasis ulcers, and epidermolysis bullosa benefited from TB4 therapy.","summary":"Summarizes Phase II dermal outcomes and safety.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:31:07.981Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"2c038e2a355cec7206da52433440dc13f310cdd4589a613a2dddc651f842f329"},{"id":"s1","type":"pubmed","url":"https://www.jeffreypengmd.com/post/tb-500-for-injury-recovery-what-the-research-actually-shows","title":"TB-500 for Injury Recovery","quote":"A phase 1 safety study in healthy volunteers demonstrated that recombinant thymosin beta-4 was well tolerated at both single and multiple intravenous doses, with no dose-limiting toxicities or serious adverse events (Wang et al., 2021). ... 84 subjects","summary":"Details Phase 1 human safety data.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:31:07.981Z","link_status":"ok","quote_status":"verified","prev":"2c038e2a355cec7206da52433440dc13f310cdd4589a613a2dddc651f842f329","hash":"1be6de2ae708aaa02bfa9a6f804a781d0a68a839ed27402960ec270796ea6ab8"},{"id":"s2","type":"review","url":"https://www.mdpi.com/2076-3417/16/12/6202","title":"Thymosin Beta-4 and TB-500 in Tissue Healing ...","quote":"Human evidence was concentrated in ocular/cornea and wound/skin/soft tissue settings ... the evidence base was weighted toward mixed and in vitro designs, and most studies evaluated TB4 rather than TB-500.","summary":"2026 scoping review grading evidence distribution.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:31:07.981Z","link_status":"http_403","quote_status":"unverified","prev":"1be6de2ae708aaa02bfa9a6f804a781d0a68a839ed27402960ec270796ea6ab8","hash":"580f8ffbd5ec02dd7a028289a6f6c36436d1cf27fed80550ae6f519b47416002"},{"id":"s23","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/10469335/","title":"Thymosin beta4 accelerates wound healing","quote":"In this study, we investigated whether the angiogenic thymic peptide thymosin beta4 (Tbeta4) enhanced wound healing in a rat full thickness wound model.","summary":"Original rat dermal wound study.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:31:07.981Z","link_status":"ok","quote_status":"verified","prev":"580f8ffbd5ec02dd7a028289a6f6c36436d1cf27fed80550ae6f519b47416002","hash":"da9fb68b6fe2c425448f449b1178a2b747661cdd07ff988c6b504a49ca9af97c"},{"id":"s19","type":"reddit","url":"https://www.reddit.com/r/USPeptides/comments/1pf55tw/bpc157_vs_tb500_which_one_should_i_take_for/","title":"BPC-157 vs TB-500","quote":"Skin closed faster and more completely, with better blood supply. Tβ4 is basically hitting fast-forward on the “close the hole and grow new vessels” part of healing.","summary":"Reddit summary of rodent-to-user translation on skin.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:31:07.981Z","link_status":"ok","quote_status":"unverified","prev":"da9fb68b6fe2c425448f449b1178a2b747661cdd07ff988c6b504a49ca9af97c","hash":"7a1670c9ef58e3ce8d0471d691306eb95a756a8fd397cb869de84515154d391d"}]}