{"slug":"tb-500-muscle-loss","verification":{"valid":true,"entries":10,"head":"809d4fc20caabde0d97add29ba1a9b019052d6abe24b4f6e576a047576fcbcb1"},"count":10,"sources":[{"id":"s1","type":"youtube","url":"https://www.youtube.com/watch?v=C9FOnvFDlSo","title":"What Science ACTUALLY Says About TB 500 Benefits","quote":"Phase 1 safety studies in healthy volunteers show that thymosin beta 4 is well tolerated even at higher doses with no dose limiting toxicities.","summary":"Video summarizes early human safety data on thymosin beta-4.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:36:07.620Z","link_status":"http_429","quote_status":"unverified","prev":"genesis","hash":"a7681e7d06bc938f8e101584cfc3c9a61841d39359d55e973d53e121bd72cdd2"},{"id":"s3","type":"other","url":"https://moonshotmp.com/learn/tb-500/","title":"TB-500 (Thymosin Beta-4): Benefits, Dosing & Side Effects","quote":"Animal studies show TB-500 accelerates muscle fiber repair after injury. It promotes satellite cell activation.","summary":"Site compiles preclinical muscle repair observations.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:36:07.620Z","link_status":"ok","quote_status":"unverified","prev":"a7681e7d06bc938f8e101584cfc3c9a61841d39359d55e973d53e121bd72cdd2","hash":"c4ce8dd2c5a932687965e21e0499fb46054f3a73ab1176bf69eb98458fdb81cc"},{"id":"s4","type":"other","url":"https://www.orthoandwellness.com/blog/tb-500-exposed-the-risks-outweigh-the-benefits","title":"TB-500 Exposed: The Risks Outweigh the Benefits","quote":"TB-500 is not approved by the U.S. Food and Drug Administration (FDA) for any medical use in humans.","summary":"Notes regulatory status clearly.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:36:07.620Z","link_status":"ok","quote_status":"unverified","prev":"c4ce8dd2c5a932687965e21e0499fb46054f3a73ab1176bf69eb98458fdb81cc","hash":"6ca353e745556e0db1d826e0c42183763b2b9603614f2e0f000b8cb38fed6117"},{"id":"s5","type":"pubmed","url":"https://journals.lww.com/jaaosglobal/fulltext/2026/01000/therapeutic_peptides_in_orthopaedics_.1.aspx","title":"Therapeutic Peptides in Orthopaedics","quote":"TB-500 is a synthetic peptide fragment derived from thymosin beta-4 (Tβ4)... promotes actin polymerization, progenitor cell recruitment, and enhanced cellular migration.","summary":"Review details actin and migration mechanisms.","claim_ids":["c3","c6"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:36:07.620Z","link_status":"ok","quote_status":"unverified","prev":"6ca353e745556e0db1d826e0c42183763b2b9603614f2e0f000b8cb38fed6117","hash":"505f3ddd954a04751b25939080a3b01f9b7db786fa7116203cd92ee4f9bd4e3e"},{"id":"s8","type":"other","url":"https://superpower.com/guides/tb-500","title":"TB-500: A Synthetic Thymosin Beta-4 Actin-Binding Fragment","quote":"Key takeaway: TB-500 is a synthetic 17-amino acid fragment of thymosin beta-4 with no completed human efficacy trials as of April 2026.","summary":"States lack of human efficacy trials.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:36:07.620Z","link_status":"ok","quote_status":"unverified","prev":"505f3ddd954a04751b25939080a3b01f9b7db786fa7116203cd92ee4f9bd4e3e","hash":"a6f1d9b8eb79b4f36ebc6942257e80b96eaa7c424576be66a07d6cf988b8fb9a"},{"id":"s9","type":"other","url":"https://www.innerbody.com/thymosin-beta-4-and-tb-500","title":"TB4 and TB-500 Peptide Therapy | What to Know in 2026","quote":"the majority of the data on TB4 (and TB-500) to date is from preclinical studies done on cells or animal subjects.","summary":"Emphasizes preclinical dominance and limited human trials.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:36:07.620Z","link_status":"ok","quote_status":"verified","prev":"a6f1d9b8eb79b4f36ebc6942257e80b96eaa7c424576be66a07d6cf988b8fb9a","hash":"f2c36262e82c1ec0677fb8bc74ff23977059509c4aee55879c0d4db20ff0e491"},{"id":"s15","type":"reddit","url":"https://www.reddit.com/r/AskMenOver30/comments/1stcht0/any_experience_with_muscletissue_repair_tb500/","title":"Any experience with muscle/tissue repair? Tb-500?","quote":"Used it after pec tear surgery, along with bpc. No idea if it actually did something though.","summary":"Example of anecdotal combined use and uncertainty.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:36:07.620Z","link_status":"ok","quote_status":"unverified","prev":"f2c36262e82c1ec0677fb8bc74ff23977059509c4aee55879c0d4db20ff0e491","hash":"57956a76ae2f8072184ec49f8d7991fdd70a4643e9cbde09c1449da7e2ed4288"},{"id":"s18","type":"reddit","url":"https://www.reddit.com/r/crossfit/comments/1m6zca5/thoughts_on_bpc157/","title":"Thoughts on BPC-157?","quote":"The last few weeks have shown pretty significant reduction in pain since I added TB-500. Is it directly related? I don't know.","summary":"User notes perceived effects with attribution doubt.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:36:07.620Z","link_status":"ok","quote_status":"unverified","prev":"57956a76ae2f8072184ec49f8d7991fdd70a4643e9cbde09c1449da7e2ed4288","hash":"b4f3d0bc19f1b3d2f361d52a7be59113ab2011bc260ad6d5459c466219714371"},{"id":"s20","type":"reddit","url":"https://www.reddit.com/r/PlantarFasciitis/comments/1bure58/bpc157_and_tb500_therapy_log/","title":"BPC-157 and TB-500 Therapy Log","quote":"Bpc-157 and tb-500 gave noticeable healing in 2 weeks.","summary":"Anecdotal healing timeline report.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:36:07.620Z","link_status":"ok","quote_status":"unverified","prev":"b4f3d0bc19f1b3d2f361d52a7be59113ab2011bc260ad6d5459c466219714371","hash":"4bece95c15aec4bd4d4ff121dbf276a326027f256d273cebb2ddaa402b08a539"},{"id":"s32","type":"other","url":"https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/thymosin-beta-4","title":"Thymosin Beta-4 - an overview","quote":"Thymosin beta-4 promotes angiogenesis, wound repair... It acts by increasing angiogenesis and cell migration.","summary":"Overview of actin and migration roles.","claim_ids":["c6"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:36:07.620Z","link_status":"http_403","quote_status":"unverified","prev":"4bece95c15aec4bd4d4ff121dbf276a326027f256d273cebb2ddaa402b08a539","hash":"809d4fc20caabde0d97add29ba1a9b019052d6abe24b4f6e576a047576fcbcb1"}]}