{"slug":"ss-31-ppis","verification":{"valid":true,"entries":3,"head":"a6893a6ccdaf56d5f7e601fe0e6dac167ad4be9692ddb435d0f3bc85d3cc319d"},"count":3,"sources":[{"id":"s1","type":"review","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10248387/","title":"Adverse Effects Associated with Long-Term Use of Proton Pump Inhibitors","quote":"The long-term use of PPIs has been linked to micronutrient deficiencies like hypomagnesemia, anemia, vitamin B12 deficiency, and hypocalcemia","summary":"Review summarizing observational links between PPIs and deficiencies.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:47:59.910Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"949ed679ed80807c825c4ed91366df686a758d899465376da74f3b5c152dc213"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/37462785/","title":"The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria","quote":"Elamipretide (ELAM) rapidly improves physiological and mitochondrial function in aging and binds directly to the mitochondrial ADP transporter ANT.","summary":"Preclinical study on SS-31 mechanism.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:47:59.910Z","link_status":"ok","quote_status":"verified","prev":"949ed679ed80807c825c4ed91366df686a758d899465376da74f3b5c152dc213","hash":"ffce76c66f07d4272306885aedf98d05abe667d7190c72c0dc7af0d760492ae9"},{"id":"s3","type":"clinical_trial","url":"https://clinicaltrials.gov/study/NCT03323749","title":"A Trial to Evaluate Safety and Efficacy of Elamipretide Primary Mitochondrial Myopathy","quote":"Phase 3 randomized, double-blind, parallel-group, placebo-controlled trial to evaluate the safety and efficacy of daily subcutaneous injections of elamipretide","summary":"Trial details confirming human study existence.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:47:59.910Z","link_status":"ok","quote_status":"unverified","prev":"ffce76c66f07d4272306885aedf98d05abe667d7190c72c0dc7af0d760492ae9","hash":"a6893a6ccdaf56d5f7e601fe0e6dac167ad4be9692ddb435d0f3bc85d3cc319d"}]}