{"slug":"ss-31-nerve-damage","verification":{"valid":true,"entries":5,"head":"ebe7d2457ebd4aeb25650d92dd7f6661336f6b087e07a6e79059ff6489489309"},"count":5,"sources":[{"id":"s9","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/42082001/","title":"Elamipretide (SS-31) promotes recovery by preserving mitochondrial bioenergetics and neural remodeling after spinal cord injury","quote":"SS-31 treatment significantly enhanced locomotor recovery and gait performance. Histological analyses showed reduced lesion pathology and increased neuronal preservation...","summary":"2026 mouse SCI study with functional and histological outcomes.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:50:59.785Z","link_status":"ok","quote_status":"unverified","prev":"genesis","hash":"094597a2cd5c38e3fef8abb532e93a944ee43b1e36022ce5bc4336111311f59e"},{"id":"s12","type":"pubmed","url":"https://link.springer.com/article/10.1186/s12974-023-02690-4","title":"Elamipretide alleviates pyroptosis in traumatically injured spinal cord by inhibiting cPLA2","quote":"SS-31 inhibited cPLA2... improved motor function after SCI.","summary":"Mechanistic SCI study linking SS-31 to autophagy and pyroptosis reduction.","claim_ids":[],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:50:59.785Z","link_status":"ok","quote_status":"unverified","prev":"094597a2cd5c38e3fef8abb532e93a944ee43b1e36022ce5bc4336111311f59e","hash":"5a796c1bc98dc0fef7c379e87aea35375f33401e6cb6f8e684eccebf01aad251"},{"id":"s0","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11816484/","title":"Elamipretide: A Review of Its Structure, Mechanism of Action...","quote":"Elamipretide (SS-31...) is a mitochondria-targeting tetrapeptide designed to treat mitochondrial dysfunction via binding to...","summary":"Review of mechanism.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:50:59.785Z","link_status":"ok","quote_status":"unverified","prev":"5a796c1bc98dc0fef7c379e87aea35375f33401e6cb6f8e684eccebf01aad251","hash":"6cf3c58eec9ad79bc580460ebb04290b960c1b7dbfa34c8772496934efa9c6d7"},{"id":"s5","type":"news","url":"https://www.fightaging.org/archives/2025/10/fda-approval-for-mitochondrial-therapeutic-elamipretide-formerly-ss-31/","title":"FDA Approval for Mitochondrial Therapeutic Elamipretide...","quote":"The approval of FORZINITY is supported by the efficacy and safety data from the TAZPOWER clinical trial.","summary":"Report on Barth syndrome approval.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:50:59.785Z","link_status":"ok","quote_status":"unverified","prev":"6cf3c58eec9ad79bc580460ebb04290b960c1b7dbfa34c8772496934efa9c6d7","hash":"62e5c3d63d310f299e7775f68603b95ef3ea12a5c5cc3cfbab2e8ad10a8d8039"},{"id":"s24","type":"reddit","url":"https://www.reddit.com/r/cfs/comments/1j2upcm/my_experience_treating_my_mecfs_with/","title":"My Experience Treating my ME/CFS with mitochondrial...","quote":"Unfortunately ss-31 elamipretide doesn't help most pwME.","summary":"CFS user discussion on SS-31.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:50:59.785Z","link_status":"ok","quote_status":"unverified","prev":"62e5c3d63d310f299e7775f68603b95ef3ea12a5c5cc3cfbab2e8ad10a8d8039","hash":"ebe7d2457ebd4aeb25650d92dd7f6661336f6b087e07a6e79059ff6489489309"}]}