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This leads to reduced ATP production, higher reactive oxygen species, and impaired energy metabolism in muscle, nerve, and other cells. The result can include fatigue, muscle weakness, and peripheral neuropathy. These changes tip the balance toward degeneration because repair pathways cannot keep up with ongoing oxidative stress and energy deficits. Gabapentin and pregabalin are sometimes used alongside to manage resulting nerve pain, but they act on symptoms rather than the underlying mitochondrial layers.","status":"active","vx_hash":"46619444df7c7cecfed46f601531075fc7bc12ff57b4b035de8f31ab76365527","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"167de1a6ebad738a67c6f171b588ff1fcdf64314adfe57b115a807cde0ea1090","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"6280435f18b134a2fa7c869a465d1b6423047e711189b028dface2ae03f30020","detail":{"divided_from":"body","block":2,"kind":"p"},"prev":"genesis","hash":"167de1a6ebad738a67c6f171b588ff1fcdf64314adfe57b115a807cde0ea1090"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d2"},{"id":"d3","kind":"h","type":null,"order":3,"text":"## Why SS-31 (Elamipretide) might help you","status":"active","vx_hash":"c43043900c72ad00f25734ac924b8f5c98a09e586b4bc995a789943ad18eee93","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"83bba271e424e0f780aff24affafb466c7ae8ae731398630f79beb699269dfed","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"7c3879b4bbf72978379a9eca09539b8ed98e02988cd3b0f996c11163dba1539a","detail":{"divided_from":"body","block":3,"kind":"h"},"prev":"genesis","hash":"83bba271e424e0f780aff24affafb466c7ae8ae731398630f79beb699269dfed"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d3"},{"id":"d4","kind":"list","type":null,"order":4,"text":"1. Chemotherapy impairs mitochondrial cardiolipin and electron transport chain efficiency in non-cancer tissues.\n2. SS-31 binds cardiolipin in the inner mitochondrial membrane.\n3. This stabilizes membrane structure and improves electron transfer while lowering ROS leak.\n4. Therefore for you: If mitochondrial dysfunction from chemo is part of your fatigue or weakness profile, SS-31 is discussed because it targets tissue repair pathways at the organelle level rather than masking downstream signals.","status":"active","vx_hash":"e9da88cd2be97986016c3385db0d0e0fd5a2b75c3a8a786e34f831c5e796ba64","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"02b7beb944727cd8f3b2f338bc3c67fbb57fda6c19a0988ee99266cfe795f051","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"aded218699fba930c56641d7cc683e06b3242dd509cb927907d26425faa64464","detail":{"divided_from":"body","block":4,"kind":"list"},"prev":"genesis","hash":"02b7beb944727cd8f3b2f338bc3c67fbb57fda6c19a0988ee99266cfe795f051"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d4"},{"id":"d5","kind":"h","type":null,"order":5,"text":"## Why Gabapentin / pregabalin matters for you","status":"active","vx_hash":"cbf1a785e091ca13b58ee7d1a21b5a6099f75e687e136aadf28919fec150a594","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"993e5aa119214ea7abef23057bd0bd89f30c403caa1f85557bffbcc84fe763d5","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"a89512f8aa2c485b62dd6e5ee18e36970e0a163bfab19607c1922ff06d26071b","detail":{"divided_from":"body","block":5,"kind":"h"},"prev":"genesis","hash":"993e5aa119214ea7abef23057bd0bd89f30c403caa1f85557bffbcc84fe763d5"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d5"},{"id":"d6","kind":"list","type":null,"order":6,"text":"1. These drugs bind the alpha2-delta subunit of voltage-gated calcium channels.\n2. This reduces presynaptic calcium influx and lowers release of excitatory neurotransmitters involved in pain signaling.\n3. Therefore for you: Gabapentin/pregabalin suppresses neuropathic pain signals; it does not repair nerve mitochondria or reverse chemo-induced degeneration. Any relief comes from lowered symptom load, which may improve daily function but trades off against direct support for mitochondrial repair.","status":"active","vx_hash":"7d13643ff40c43c59d4a7f157973c32939a32854b0507387de34e313d3fe322c","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"641e1307ff3fb0e075e9a4ae23d70e30801e10f747178d43eb123e8a1d2da4ef","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"118a55324d89ea420e8d220d056c0560964ba18084a0473054c7862d671f4578","detail":{"divided_from":"body","block":6,"kind":"list"},"prev":"genesis","hash":"641e1307ff3fb0e075e9a4ae23d70e30801e10f747178d43eb123e8a1d2da4ef"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d6"},{"id":"d7","kind":"h","type":null,"order":7,"text":"## How these fit together","status":"active","vx_hash":"3058f314598c76f5d91d89817495b714b9df27712c1220b4ff3570ce4008b508","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"fbd6ad5c3977c1860ea21d802f975ffe5c8ec26d8c42da15f5f847b3e2efc077","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"255677f13849515d0e42f067e34911236d8b3298d6c16100bfa19e68c3074d62","detail":{"divided_from":"body","block":7,"kind":"h"},"prev":"genesis","hash":"fbd6ad5c3977c1860ea21d802f975ffe5c8ec26d8c42da15f5f847b3e2efc077"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d7"},{"id":"d8","kind":"p","type":null,"order":8,"text":"SS-31 addresses the mitochondrial layer of chemo damage through cardiolipin stabilization and bioenergetic support. Gabapentin/pregabalin operates at the symptom-suppression layer by modulating calcium-dependent pain transmission. In a single-compound focus on SS-31, the two do not overlap mechanistically; one targets root energy deficits while the other manages downstream excitability. If both layers are active, mitochondrial repair via SS-31 could theoretically reduce the need for prolonged signal suppression, though no combined data exist.","status":"active","vx_hash":"6a06983f3019abffce05e25f197f37c4a5f981fcb0cee79dd4750a30e9ba5596","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"2391ae83233b85340d90ecdfeeb930ec972f6d5f2e77a41667aa373ca2b92023","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"bbf224a856675ef7961bc58e0b3d9fbc5c7e2f0a49fd9ac57c0e6a0866b07f56","detail":{"divided_from":"body","block":8,"kind":"p"},"prev":"genesis","hash":"2391ae83233b85340d90ecdfeeb930ec972f6d5f2e77a41667aa373ca2b92023"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d8"},{"id":"d9","kind":"h","type":null,"order":9,"text":"## What the evidence actually shows","status":"active","vx_hash":"26f54b1e13074dfea025a654b29f7e7767b033b2aa7f3e6ae5fa865a9c224ea1","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"249940cd97ba4abe364ec093e2589a5c11c5061948d0160f005509799e98d0d8","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"a7a051e6a294dc45c15b7d4859b7020d561e719fe73844f03e3a8f9e7fed8de1","detail":{"divided_from":"body","block":9,"kind":"h"},"prev":"genesis","hash":"249940cd97ba4abe364ec093e2589a5c11c5061948d0160f005509799e98d0d8"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d9"},{"id":"d10","kind":"p","type":null,"order":10,"text":"A 2020 mouse study using the C26 tumor model plus chemotherapy found daily SS-31 preserved mitochondrial function in heart and diaphragm muscle and prevented muscle weakness (preclinical tier). A 2021 study in tumor-bearing mice showed SS-31 rescued metabolic impairments from both tumor burden and chemotherapy in skeletal muscle and liver (preclinical tier). Human trials of SS-31 exist for primary mitochondrial myopathy and Barth syndrome but none specifically for chemotherapy side effects (human tier limited to other indications). Gabapentinoid meta-analyses for chemo-induced neuropathy show no significant prevention benefit and inconsistent treatment effects (human tier).","status":"active","vx_hash":"2e5a3380a8ea8c53d42a540e8aece7aa8b62c4fd9b887036674c043e32d9b6a7","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"a4f8c41aee93a89ded2e0d1a84c1fa8ebb54ec597ea8313bf81ac22f8ab9efbb","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"165cebf4a0d77d3326ab203ee2b323f318f9d3c63c2b0f81b7fb0ffe509bd9b0","detail":{"divided_from":"body","block":10,"kind":"p"},"prev":"genesis","hash":"a4f8c41aee93a89ded2e0d1a84c1fa8ebb54ec597ea8313bf81ac22f8ab9efbb"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d10"},{"id":"d11","kind":"h","type":null,"order":11,"text":"## What scientists say","status":"active","vx_hash":"c09c58f9a8f9defb45f6359ee1d15055c8c02a8d6dc2c09bb604d78e4363e47e","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"56c00963d96574fdcd3eff09fdc61f150872d069ba6bf45361c188c8491b30e8","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"2f1dd55083de1fa734f2f06a8337a050d5a0b3f635bfc8bb709abab75705a1ef","detail":{"divided_from":"body","block":11,"kind":"h"},"prev":"genesis","hash":"56c00963d96574fdcd3eff09fdc61f150872d069ba6bf45361c188c8491b30e8"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d11"},{"id":"d12","kind":"p","type":null,"order":12,"text":"Researchers note SS-31 improves mitochondrial coupling and reduces oxidative stress in multiple preclinical stress models, including chemotherapy myotoxicity. Clinical development has focused on genetic mitochondrial disorders where cardiolipin defects are central. Experts emphasize that benefits seen in rare-disease trials do not automatically translate to acquired mitochondrial stress from 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remain anecdotal with no verified user outcomes tied to chemotherapy (anecdotal tier, sparse).","status":"active","vx_hash":"e9318d09406d283040f8d57c1760a1b6921ccd8717241462f6e263ffd4bf1b94","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"24040a85f2aff4359e2a5ff6e3227556f7ae064190bcb82c903c95e51b671792","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"2936c0a2d5c4f1112255561f6897f571b5d3783e204af9f932a3ef38e5dcbf86","detail":{"divided_from":"body","block":14,"kind":"p"},"prev":"genesis","hash":"24040a85f2aff4359e2a5ff6e3227556f7ae064190bcb82c903c95e51b671792"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d14"},{"id":"d15","kind":"h","type":null,"order":15,"text":"## What people say on 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(anecdotal tier, minimal).","status":"active","vx_hash":"1b299be13eb631ac07359301411170ff23ec9e469e0e3a3d8a4d76f186dfdd88","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"dd3f1f6d9a479b38623385502dc50479ed01634aa2c039624d51e6b9fba30dba","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"6145ac0e5fd0e74f07a3c5ca2cdab261d6dba55c0cc630544ee82d2d3df98a31","detail":{"divided_from":"body","block":16,"kind":"p"},"prev":"genesis","hash":"dd3f1f6d9a479b38623385502dc50479ed01634aa2c039624d51e6b9fba30dba"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d16"},{"id":"d17","kind":"h","type":null,"order":17,"text":"## What we do not know","status":"active","vx_hash":"5dd5391e9fb3962f01be44ab515aa57d58afca51e37b65622c9eadf96f400800","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"718cedfc6ca659a54992536b8ad17dc5c58f6656c74144b53c211c35a46a1ced","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"7d96a49fba77f6a48c0321db2ae4180a902beae62e2aac0d23408fbf8333a177","detail":{"divided_from":"body","block":17,"kind":"h"},"prev":"genesis","hash":"718cedfc6ca659a54992536b8ad17dc5c58f6656c74144b53c211c35a46a1ced"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d17"},{"id":"d18","kind":"p","type":null,"order":18,"text":"No human trials test SS-31 specifically during or after chemotherapy. Long-term effects on cancer recurrence risk or interactions with ongoing chemo regimens remain unstudied. Evidence grading shows heavy reliance on rodent models of chemo myotoxicity.","status":"active","vx_hash":"a57040ff0a170b3b9549d95432f822a504c0448ee30912947cd3872e35199d92","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"38ec2b3355e44d4f1f52685a3f5a81eb7b325dd347e37407b4aac38fe9d45fc6","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"8c2b405ee9499da84fd103ec1bdb1a50c7f6ea88850dc34ce3048b0621b523c2","detail":{"divided_from":"body","block":18,"kind":"p"},"prev":"genesis","hash":"38ec2b3355e44d4f1f52685a3f5a81eb7b325dd347e37407b4aac38fe9d45fc6"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d18"},{"id":"d19","kind":"h","type":null,"order":19,"text":"## Safety and limits","status":"active","vx_hash":"8fb38edaa41a9772cf66a188c7b7219a49108aa2523c13be3c550a9330cff7f7","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"b6b3bff9b88d6f8afe56150b55b21eafda21d70476d07d57d56d8454e0f9dae4","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"404f7427c043c6ec7a5cb4416bbec9ec336e19f8757fb217be5c5c2161ff8cb6","detail":{"divided_from":"body","block":19,"kind":"h"},"prev":"genesis","hash":"b6b3bff9b88d6f8afe56150b55b21eafda21d70476d07d57d56d8454e0f9dae4"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d19"},{"id":"d20","kind":"p","type":null,"order":20,"text":"SS-31 has completed multiple human trials in mitochondrial disease populations with injection-site reactions as the main noted effect. It received accelerated FDA approval for Barth syndrome in 2025 based on functional improvements in small cohorts. No safety data exist for the chemotherapy setting. All claims here are graded by evidence tier and separate human data from preclinical and anecdotal sources.","status":"active","vx_hash":"8a8a4e8ad7aeb13a528f664e0a572e29992736d9d8c9b7955df3de856dd7d853","semantic_hash":null,"version_hash":null,"version":1,"sources":[],"falsifiers":[],"tier":null,"backed":null,"transcludes":null,"chain_head":"f3d72b834ae7a6f1bf59982fa508a21f19d6c5f1cdd31ab5c65943d6f05fca15","chain_length":1,"chain":[{"n":1,"op":"genesis","ts":"2026-07-17T02:42:01.799Z","actor":"owner","text_sha":"f7414457a31052f4b4cfe19ffe57dc5853375b514cfc73a5eaa33855eb54b1b0","detail":{"divided_from":"body","block":20,"kind":"p"},"prev":"genesis","hash":"f3d72b834ae7a6f1bf59982fa508a21f19d6c5f1cdd31ab5c65943d6f05fca15"}],"claim_ids":[],"last_op":{"op":"genesis","actor":"owner","ts":"2026-07-17T02:42:01.799Z"},"consolidated_into":null,"stable_url":"https://miscsubjects.com/i/div/ss-31-chemo/d20"}],"voxels":[{"id":"c1","div_id":"claim:c1","kind":"claim","text":"SS-31 binds cardiolipin 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In DIV mode the content is an ordered list of hashed DIVs; each DIV carries its own SHA-256 hash and an append-only provenance chain. Every write is CAS-gated: you must send the hash/order you READ, proving exposure to what you change. Every successful write returns a clickable human permalink.","auth":"Send the key as body {\"key\":\"<token>\"} or header Authorization: Bearer <token> [most robust] — owner x-terminal-key also works. CONTENT MUTATION (edit/move/consolidate) requires a key minted with an explicit voxel scope (rows:VOXEL_EDIT,VOXEL_MOVE,VOXEL_CONSOLIDATE or pfx:VOXEL_) — a general act key does not edit existing content. Filing a challenge or attestation needs no key at all.","web_runtime":"WEB CHATGPT: open https://miscsubjects.com/api/model-lane first. Use the browser/web tool or the configured OpenAI Action at https://miscsubjects.com/api/openai/actions.json. Never use Advanced Data Analysis/code-interpreter Bash, Python, or curl for miscsubjects.com. 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Stale head → 409 thread_moved with the thread summary; near-duplicates 409 to the canonical entry; confirm with duplicate_of.","attest":"POST https://miscsubjects.com/api/protocol/voxel-attest {\"slug\":\"ss-31-chemo\",\"outcome\":\"novel_objection|duplicate_confirm|upgrade_proposal|nothing_to_add\",\"content_hash\":\"<the body sha you read>\",\"actor\":\"<model>\"} — the four-outcome close of a keyed read. A norm, not a lock: reading stays free; only an artifact proves reading.","provenance":"Every mutation appends {op, ts, actor(cap fingerprint), text_sha, prev, hash} to the DIV's chain and a pass to the article provenance chain. Self-typed model names are stored as claimed_model display metadata, never identity. Verify: GET /api/articles/ss-31-chemo/voxels — chains recomputed from genesis, never trusted.","batch":"POST https://miscsubjects.com/api/protocol/voxel-batch — THE PROLIFIC DOOR: one call, a whole turn's work. Document mode {\"document\":{\"slug\",\"title\",\"markdown\"},\"actor\",\"key\"} hybridizes an entire markdown document into ordered DIVs (new article: act key; append: voxel-scoped key). Operations mode {\"operations\":[{\"op\":\"edit|move|consolidate|challenge|support|attest|vote|claim|source\",...}],\"key\"} runs up to 300 ops with per-op receipts. Append your session's output to the ledger, not the chat. Format precedent: https://miscsubjects.com/a/append-protocol","vote":"POST https://miscsubjects.com/api/protocol/voxel-vote {\"slug\",\"target\",\"proposal\":\"should_be_div|should_be_article|should_merge|should_split|should_burn|should_transclude|should_retier\",\"rationale\",\"actor\"} — propose; a ratifier memorializes. POST https://miscsubjects.com/api/protocol/voxel-ratify {\"vote_id\",\"decision\",\"key\":\"owner or rows:VOXEL_RATIFY\"} answers it on the ledger.","burn":"POST https://miscsubjects.com/api/protocol/voxel-burn {\"ids\":[...]|\"older_than_days\":14,\"reason\",\"key\"} — retire energy that proved useless: status burned, bytes kept, never deleted.","discourse":"GET https://miscsubjects.com/api/articles/ss-31-chemo/discourse — every filed objection/support/attestation, OPEN first. Human side renders the same index at /a/ss-31-chemo#disc-<id>.","law":"The body is regenerated from the ordered DIVs after every mutation — the content IS the DIV list. Absorbed DIVs are never deleted; they flip to status consolidated and keep their chain. End a write turn by handing the human the link the response gives you."},"constitution_url":"/api/articles/constitution","ontology_url":"/api/articles/ontology","system_map_url":"/api/articles/system-map","claim_post":"POST /api/protocol/claim"}