{"slug":"ss-31-chemo","verification":{"valid":true,"entries":4,"head":"be4c2d147f8e3765c6c7eb6b309bc4ddf170364040b816aaea46c179aae34350"},"count":4,"sources":[{"id":"s1","type":"review","url":"https://biomeme.com/applications/wellness/peptide-evidence/ss-31/","title":"SS-31 (Elamipretide) — Peptide Evidence Score","quote":"SS-31 selectively targets and stabilizes cardiolipin in the inner mitochondrial membrane.","summary":"Mechanism summary for cardiolipin binding and bioenergetics.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:57:52.474Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"981eca55da2f81f9a3d15193a9cc6f03432f2b98757fc5f8a16ead1aa3c33d78"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/31747905/","title":"Pharmacological targeting of mitochondrial function and ROS production...","quote":"SS-31 treatment preserved mitochondrial function in both cardiac and diaphragm muscle from C26 mice","summary":"Preclinical chemo model results.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:57:52.474Z","link_status":"ok","quote_status":"unverified","prev":"981eca55da2f81f9a3d15193a9cc6f03432f2b98757fc5f8a16ead1aa3c33d78","hash":"86863e84e0b1ecd5a439295fd642ba96793c02be4fecbd7fca1c2d90f4571b45"},{"id":"s3","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/38936970/","title":"Gabapentinoids for chemotherapy-induced peripheral neuropathy","quote":"pregabalin did not significantly improve average pain... limited evidence to support the use of gabapentinoids in CIPN","summary":"Meta-analysis on gabapentinoids in CIPN.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:57:52.474Z","link_status":"ok","quote_status":"unverified","prev":"86863e84e0b1ecd5a439295fd642ba96793c02be4fecbd7fca1c2d90f4571b45","hash":"ee2e0f1c2dc41bec24f734c1d23521628ac06d0541858a94ba3c034e1518724a"},{"id":"s4","type":"news","url":"https://hub.jhu.edu/2025/09/25/fda-approves-barth-syndrome-treatment/","title":"FDA approves drug for treatment of rare mitochondrial disorder","quote":"FDA grants accelerated approval first treatment Barth syndrome","summary":"Human trial and approval data for elamipretide.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T23:57:52.474Z","link_status":"ok","quote_status":"unverified","prev":"ee2e0f1c2dc41bec24f734c1d23521628ac06d0541858a94ba3c034e1518724a","hash":"be4c2d147f8e3765c6c7eb6b309bc4ddf170364040b816aaea46c179aae34350"}]}