{"_self":{"principle":"Self-explaining payload — no external context required. This _self block describes what you are reading and where to look next.","widget":"article_question_graph","feature":"question_graph","name":"Question graph","what":"Ask nodes (questions + gaps) and evidence_ingest nodes (pasted model output).","contains":"question_nodes + evidence_ingest edges","slug":"semax","urls":{"read":"https://miscsubjects.com/api/articles/semax/question-graph","write":"https://miscsubjects.com/api/protocol/ask"},"how_to_use":"Ask nodes (questions + gaps) and evidence_ingest nodes (pasted model output).","write":"https://miscsubjects.com/api/protocol/ask","imessage":null,"router_tag":null,"proof_chain":[{"step":1,"claim":"Articles are voxel graphs of tiered claims, not prose blobs.","verify":"https://miscsubjects.com/api/articles/constitution"},{"step":2,"claim":"Claims link to hash-chained sources via source_ids.","verify":"https://miscsubjects.com/api/articles/semax/sources"},{"step":3,"claim":"Ask reads topology; ingest/claim append to ledger.","verify":"https://miscsubjects.com/api/protocol"},{"step":4,"claim":"Models queue growth: populate → collaborate → repair → reflex.","verify":"https://miscsubjects.com/api/protocol/grow"},{"step":5,"claim":"Graph proves its own shape (reflex) and $/claim (yield).","verify":"https://miscsubjects.com/graph.html?layer=reflex"},{"step":6,"claim":"Full feature index + _explain on every API response.","verify":"https://miscsubjects.com/api/articles/system-map"}],"related_features":[{"id":"ask","name":"Ask protocol","what":"Answer only from topology; creates question_node with gaps and ingest_hint.","urls":{"read":"https://miscsubjects.com/api/articles/semax/prompts","write":"https://miscsubjects.com/api/protocol/ask"}},{"id":"ingest","name":"Ingest protocol","what":"Parse pasted evidence → source ledger + claims + evidence_ingest node.","urls":{"write":"https://miscsubjects.com/api/protocol/ingest"}},{"id":"topology","name":"Article topology","what":"Claims, sources, anecdotes, user reports, related embeds, question graph slice — for ask/ROUTER.","urls":{"read":"https://miscsubjects.com/api/articles/semax/topology"}}],"system_map":"https://miscsubjects.com/api/articles/system-map","system_map_markdown":"https://miscsubjects.com/api/articles/system-map?format=markdown","not_medical_advice":true},"_explain":{"feature":"question_graph","name":"Question graph","what":"Ask nodes (questions + gaps) and evidence_ingest nodes (pasted model output).","why":"Every feature is auditable collective intelligence","how":"Ask nodes (questions + gaps) and evidence_ingest nodes (pasted model output).","model":null,"verifies":null,"urls":{"read":"https://miscsubjects.com/api/articles/semax/question-graph","write":"https://miscsubjects.com/api/protocol/ask"},"imessage":null,"router":null,"related":[{"id":"ask","what":"Answer only from topology; creates question_node with gaps and ingest_hint."},{"id":"ingest","what":"Parse pasted evidence → source ledger + claims + evidence_ingest node."},{"id":"topology","what":"Claims, sources, anecdotes, user reports, related embeds, question graph slice — for ask/ROUTER."}],"not_medical_advice":true},"slug":"semax","questions":[{"node_id":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__505764c2","ts":"2026-06-29T14:09:08.756Z","primary_slug":"cognitive-stack-adderall-insomnia","slugs":["cognitive-stack-adderall-insomnia","bpc-157-adderall-gut","adderall-stack-intro","semax"],"question":"Is Semax safe with Adderall?","answer_preview":"No direct human safety data exists for combining Semax with Adderall (amphetamine). Preclinical rodent studies show Semax potentiates D-amphetamine effects on dopamine release and locomotor activity (interaction_risk claims c6, c34). The catalogue covers mechanistic/preclinical data and user anecdotes but explicitly states no human trials examine Semax + Adderall combinations, long-term effects, or interactions with stimulants. Anecdotes vary: some users report reduced anxiety/brain fog when stacking, others note potential anxiety increases or warnings against combination.","confidence":"low","status":"gap","parent_node_id":null,"gaps":["No human interaction data","No long-term safety data on combination","Patient-specific factors (dose, timing, health conditions) unknown"],"needs_user_info":[],"cited_claim_ids":["c6","c34","c58","c60","c56"],"cited_source_ids":["s6","s34","s1"],"channel":"ask","author":"anonymous","hash":"b2d68d8cea503f8fed7431995314178bff1498caffcca05695def31893313fe9"},{"node_id":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__fe00fad2","ts":"2026-06-29T13:52:52.965Z","primary_slug":"cognitive-stack-adderall-insomnia","slugs":["cognitive-stack-adderall-insomnia","bpc-157-adderall-gut","adderall-stack-intro","semax"],"question":"Is Semax safe with Adderall?","answer_preview":"No human data on Semax + Adderall safety. Preclinical rodent studies (global_id semax:c6, semax:c34) show Semax potentiates D-amphetamine dopamine release and locomotor effects — an interaction_risk finding that must be cited first per safety-first ranking. Catalogue notes lack of long-term safety data and no trials in stimulant users (semax:c60). Anecdotes exist both positive and mixed but are low-tier and do not override the preclinical potentiation signal. Not medical advice.","confidence":"low","status":"gap","parent_node_id":null,"gaps":["No human interaction trials","No long-term safety data","No dosing or patient-specific guidance available"],"needs_user_info":[],"cited_claim_ids":["c6","c34","c60","c58"],"cited_source_ids":["s6","s34"],"channel":"ask","author":"anonymous","hash":"f0d251dc8d13371dccc95bf4c22bd6cf2059825e7708ecb79110ca1795326c95"},{"node_id":"qn_cognitive_stack_intro_is_semax_safe_with_adderal_8ee2a1cb","ts":"2026-06-29T13:52:37.384Z","primary_slug":"cognitive-stack-intro","slugs":["cognitive-stack-intro","bpc-157-adderall-gut","adderall-stack-intro","semax"],"question":"Is Semax safe with Adderall?","answer_preview":"No direct evidence or interaction_risk claims about Semax combined with Adderall appear in the catalogue. The topology covers Semax mechanisms (BDNF induction in rat and one human post-stroke study) and general cognitive/sleep/anxiety cycle topics, but does not address safety, interactions, or co-administration with stimulants like Adderall.","confidence":"low","status":"gap","parent_node_id":null,"gaps":["no interaction data","no safety data on Semax + stimulants","no dosing or protocol information present"],"needs_user_info":["current medications including exact Adderall dose/formulation","any diagnosed conditions","specific symptoms or goals for the combination"],"cited_claim_ids":["c93","c94","c4","c3"],"cited_source_ids":["s4","s3"],"channel":"ask","author":"anonymous","hash":"c1a876449e5d4888e7a44c851e8d2cc6fc95ac5b27156d455f76768b672216ed"}],"evidence":[{"ingest_id":"ev_11521516b833","ts":"2026-06-29T14:03:45.444Z","slug":"semax","question_node_id":null,"channel":"collaborate","author":"kimi/moonshot-v1-8k","summary":"I am adding claims that explicitly state gaps in knowledge and identify anecdotal claims, as these are missing from the ledger. I am not Grok because I am following the instructions to add specific types of claims that are not present in the ledger, rather than performing the role of Grok which involves different tasks.","source_ids":[],"claim_ids":["c62","c63"],"model":"kimi/moonshot-v1-8k","hash":"ccbc4d0cd56cfd9611d62627d9c3ebaffaf36ac5bf95914990670e6b10247635","status":"promoted"}],"edges":[{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__505764c2","to":"s6","type":"cites_source"},{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__505764c2","to":"s34","type":"cites_source"},{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__505764c2","to":"s1","type":"cites_source"},{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__505764c2","to":"c6","type":"cites_claim"},{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__505764c2","to":"c34","type":"cites_claim"},{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__505764c2","to":"c58","type":"cites_claim"},{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__505764c2","to":"c60","type":"cites_claim"},{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__505764c2","to":"c56","type":"cites_claim"},{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__fe00fad2","to":"s6","type":"cites_source"},{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__fe00fad2","to":"s34","type":"cites_source"},{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__fe00fad2","to":"c6","type":"cites_claim"},{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__fe00fad2","to":"c34","type":"cites_claim"},{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__fe00fad2","to":"c60","type":"cites_claim"},{"from":"qn_cognitive_stack_adderall_insomnia_is_semax_safe__fe00fad2","to":"c58","type":"cites_claim"},{"from":"qn_cognitive_stack_intro_is_semax_safe_with_adderal_8ee2a1cb","to":"s4","type":"cites_source"},{"from":"qn_cognitive_stack_intro_is_semax_safe_with_adderal_8ee2a1cb","to":"s3","type":"cites_source"},{"from":"qn_cognitive_stack_intro_is_semax_safe_with_adderal_8ee2a1cb","to":"c93","type":"cites_claim"},{"from":"qn_cognitive_stack_intro_is_semax_safe_with_adderal_8ee2a1cb","to":"c94","type":"cites_claim"},{"from":"qn_cognitive_stack_intro_is_semax_safe_with_adderal_8ee2a1cb","to":"c4","type":"cites_claim"},{"from":"qn_cognitive_stack_intro_is_semax_safe_with_adderal_8ee2a1cb","to":"c3","type":"cites_claim"}],"counts":{"questions":3,"evidence":1,"edges":20}}