{"slug":"semax-tirzepatide","verification":{"valid":true,"entries":3,"head":"906580ce135d8708ca834ce241813a81eddbef5af98c81755b7d4d9186a45af2"},"count":3,"sources":[{"id":"s0","type":"pubmed","url":"https://www.alzdiscovery.org/uploads/cognitive_vitality_media/Semax-Cognitive-Vitality-For-Researchers.pdf","title":"Semax Cognitive Vitality For Researchers","quote":"Another study in 110 patients with stroke reported that treatment with semax (2 courses 6000 µg/day for 10 days with 20-day interval) increased plasma BDNF levels.","summary":"Summary of Russian stroke trial data on BDNF.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:01:06.304Z","link_status":"ok","quote_status":"unverified","prev":"genesis","hash":"acfb4dc417073e28ae1c328dfb81eaeb59964d036d431960bd70b2c4331e11d9"},{"id":"s2","type":"pubmed","url":"https://www.sciencedirect.com/science/article/abs/pii/S0006899306022955","title":"Semax, an analog of ACTH(4–10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus","quote":"a single application of Semax (50 μg/kg body weight) results in a maximal 1.4-fold increase of BDNF protein levels... and a 3-fold and a 2-fold increase of exon III BDNF and trkB mRNA levels","summary":"Rat study demonstrating BDNF upregulation.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:01:06.304Z","link_status":"http_403","quote_status":"unverified","prev":"acfb4dc417073e28ae1c328dfb81eaeb59964d036d431960bd70b2c4331e11d9","hash":"b47a6ff0999d72fc5e628c9adcf19672cea3938ee87d9630eec0a5334adf667a"},{"id":"s10","type":"other","url":"https://nwregen.com/articles/beyond-the-scale-the-surprising-benefits-of-tirzepatide-for-joint-and-metabolic-health/","title":"The Benefits of Tirzepatide for Joint and Metabolic Health","quote":"For every pound of excess weight, the joints can experience up to four additional pounds of pressure with each step.","summary":"Biomechanical load estimate for weight loss.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:01:06.304Z","link_status":"ok","quote_status":"verified","prev":"b47a6ff0999d72fc5e628c9adcf19672cea3938ee87d9630eec0a5334adf667a","hash":"906580ce135d8708ca834ce241813a81eddbef5af98c81755b7d4d9186a45af2"}]}