{"slug":"semax-statin-brain-fog","verification":{"valid":true,"entries":4,"head":"0f5dc6ac55dadc6f17c0f264ec4c9612151381bcf00fbd336337b7d95a57976e"},"count":4,"sources":[{"id":"s1","type":"medical","url":"https://www.lipid.org/lipid-spin/summer-2020/guest-editorial-statins-and-brain-fog-confusing-patients-prescribers-and-me","title":"Statins and Brain Fog: Confusing for Patients, Prescribers, and Me","quote":"There have been rare post-marketing reports of cognitive impairment (e.g.,memory loss, forgetfulness, amnesia, memory impairment, confusion) associated with statin use.","summary":"Reviews post-marketing reports and large trial data on statins and cognition.","claim_ids":["c1","c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T09:16:10.130Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"10c3e1098701e297c5da0f242d14021deed7ba26c35312a3da1dc8f092f289ba","source_role":"adjacent_context"},{"id":"s10","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/16996037/","title":"Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus","quote":"a single application of Semax (50 microg/kg body weight) results in a maximal 1.4-fold increase of BDNF protein levels... 3-fold and a 2-fold increase of exon III BDNF and trkB mRNA levels, respectively, in the rat hippocampus.","summary":"Preclinical rat study on Semax, BDNF, and cognitive effects.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T09:16:10.130Z","link_status":"ok","quote_status":"unverified","prev":"10c3e1098701e297c5da0f242d14021deed7ba26c35312a3da1dc8f092f289ba","hash":"6f30326c32bd8259129d1048f2e43e8cecf3a54aed8dc9cd3e7bd9f1c2f05976","source_role":"core_stack_evidence"},{"id":"s6","type":"review","url":"https://www.healthline.com/health/high-cholesterol/link-between-statins-and-memory-loss","title":"Statins and Memory Loss: Is There a Link?","quote":"Current research does not demonstrate a definitive connection between statin use and memory loss, and some studies suggest statins may even have a protective effect against dementia.","summary":"Summarizes reviews finding no link or possible protection.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T09:16:10.130Z","link_status":"ok","quote_status":"verified","prev":"6f30326c32bd8259129d1048f2e43e8cecf3a54aed8dc9cd3e7bd9f1c2f05976","hash":"0fe55a3f780d6906007d2ebfda05e41c86504bfc0e6b7190a07bf94cb8c85592","source_role":"adjacent_context"},{"id":"s14","type":"other","url":"https://peptiq.io/blog/semax-nootropic-peptide-guide","title":"Semax: The Neuroprotective Peptide Changing Cognitive Research","quote":"In a randomized controlled trial (Gusev et al., Cerebrovascular Diseases, 2005), Semax administered intranasally in the acute phase was associated with reduced neurological deficit scores...","summary":"Notes human stroke data but no statin-specific trials.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-29T09:16:10.130Z","link_status":"ok","quote_status":"unverified","prev":"0fe55a3f780d6906007d2ebfda05e41c86504bfc0e6b7190a07bf94cb8c85592","hash":"0f5dc6ac55dadc6f17c0f264ec4c9612151381bcf00fbd336337b7d95a57976e","source_role":"core_stack_evidence"}]}