{"slug":"semax-semaglutide","verification":{"valid":true,"entries":5,"head":"1c6baa8a5d622215dbabe9d70c13147afcf73a1f5b3bfe3def593be0343f9e69"},"count":5,"sources":[{"id":"web:16","type":"pubmed","url":"https://www.sciencedirect.com/science/article/abs/pii/S0006899306022955","title":"Semax regulates BDNF and trkB expression in the rat hippocampus","quote":"a single application of Semax (50 μg/kg body weight) results in a maximal 1.4-fold increase of BDNF protein levels... and a distinct increase in the number of conditioned avoidance reactions.","summary":"Rat study on BDNF upregulation and learning.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:04:05.914Z","link_status":"http_403","quote_status":"unverified","prev":"genesis","hash":"29fe1bd80df186970deeecf5e3347e3368532c977914761628526edbb9dcc3d3"},{"id":"web:17","type":"pubmed","url":"https://www.researchgate.net/publication/325375504_The_efficacy_of_semax_in_the_tretament_of_patients_at_different_stages_of_ischemic_stroke","title":"Efficacy of semax in ischemic stroke patients","quote":"Administration of semax... increased BDNF plasma levels... positively correlated with early rehabilitation.","summary":"Human stroke cohort BDNF and recovery data.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:04:05.914Z","link_status":"http_403","quote_status":"unverified","prev":"29fe1bd80df186970deeecf5e3347e3368532c977914761628526edbb9dcc3d3","hash":"f1879641c64d460c5c399d0eb351f966420c8f0b015d09a55d57f55659ef28ca"},{"id":"web:3","type":"other","url":"https://spineteamtexas.com/resources/blog/back-pain-and-glp-1-assisted-weight-loss-a-new-path-to-relief/","title":"Back Pain and GLP-1 Assisted Weight Loss","quote":"For someone who loses 30 pounds on semaglutide, this could mean up to 120 pounds less pressure on the spine","summary":"Mechanical load reduction estimate from weight loss.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:04:05.914Z","link_status":"ok","quote_status":"unverified","prev":"f1879641c64d460c5c399d0eb351f966420c8f0b015d09a55d57f55659ef28ca","hash":"a655ca7f888ca2d75a9f5313a856c21caad7f1d5b6a69fa4ad2de4b66f67c483"},{"id":"web:4","type":"other","url":"https://www.jeremyburnhammd.com/glp-1s-and-bone-health-what-the-evidence-says-about-semaglutide-bone-density-and-muscle-loss/","title":"GLP-1s and Bone Health","quote":"52 weeks of once-weekly semaglutide reduced hip bone mineral density by 2.6% and lumbar spine by 2.1%","summary":"Human RCT bone density changes with semaglutide.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:04:05.914Z","link_status":"ok","quote_status":"unverified","prev":"a655ca7f888ca2d75a9f5313a856c21caad7f1d5b6a69fa4ad2de4b66f67c483","hash":"224ad7ac391014b7da2ae2d5d89d0a6ee096297b65ba9f28dd72aa6097a163f5"},{"id":"web:22","type":"other","url":"https://trimrx.com/blog/semax-stacking-with-glp1/","title":"Semax: Can You Stack It with GLP-1 Medications?","quote":"no controlled human trial has tested the combination","summary":"Absence of combination trial data.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:04:05.914Z","link_status":"ok","quote_status":"verified","prev":"224ad7ac391014b7da2ae2d5d89d0a6ee096297b65ba9f28dd72aa6097a163f5","hash":"1c6baa8a5d622215dbabe9d70c13147afcf73a1f5b3bfe3def593be0343f9e69"}]}