{"slug":"semax-sciatica","verification":{"valid":true,"entries":7,"head":"ede960b1e41b4501fa900184d854693782fa0988873c293180bd30cc6b0ade8d"},"count":7,"sources":[{"id":"s1","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/29798983/","title":"The efficacy of semax in the treatment of patients at different stages of ischemic stroke","quote":"Administration of semax, regardless of the timing of rehabilitation, increased BDNF plasma levels which remained high during the whole study period.","summary":"110-patient stroke study showing BDNF increase and functional gains with semax.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:04:01.194Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"6a15f8716eef7bef15bdda416598e390e22ac0a7fa259694a9b7dcea81bd0100"},{"id":"s2","type":"pubmed","url":"https://link.springer.com/article/10.1007/s11055-012-9562-6","title":"The Nootropic and Analgesic Effects of Semax Given via Different Routes","quote":"Intranasal Semax was more effective in improving learning in animals than i.p. Semax but had no effect on pain sensitivity.","summary":"Rat study on semax effects by route.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:04:01.194Z","link_status":"ok","quote_status":"verified","prev":"6a15f8716eef7bef15bdda416598e390e22ac0a7fa259694a9b7dcea81bd0100","hash":"e6267362b683c526dbd5738780c69eb76435936ab9ef2d9ddd404597e5918cde"},{"id":"s3","type":"other","url":"https://peptides628.com/bpc-157-nerve-regeneration-sciatic-nerve-rat-serum/","title":"BPC-157 nerve regeneration sciatic nerve rat","quote":"BPC 157 markedly improved rat sciatic nerve healing and exhibited faster axonal regeneration","summary":"Summary of rat sciatic nerve BPC-157 studies.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:04:01.194Z","link_status":"ok","quote_status":"unverified","prev":"e6267362b683c526dbd5738780c69eb76435936ab9ef2d9ddd404597e5918cde","hash":"6dcd029cbe4879a7faf4bb6d882623ebfad2632441c65d29245a258d21d6644d"},{"id":"s4","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3533234/","title":"Thymosin β4 Promotes the Recovery of Peripheral Nerve Function in Diabetic Neuropathy","quote":"The present study indicates that Tβ4 ameliorates diabetic peripheral neuropathy, evidenced by reduction of sciatic nerve conduction velocity deficits.","summary":"Rat diabetic neuropathy study with thymosin beta-4.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:04:01.194Z","link_status":"ok","quote_status":"unverified","prev":"6dcd029cbe4879a7faf4bb6d882623ebfad2632441c65d29245a258d21d6644d","hash":"287ea93f24ad80a98c1a6981c982b765588f7c48994ec33fd5c3e8387558baaa"},{"id":"s5","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/24555851/","title":"ARA 290 for treatment of small fiber neuropathy in sarcoidosis","quote":"ARA 290 treatment was consistently associated with a significant improvement of neuropathic pain symptoms in sarcoidosis patients.","summary":"Human trial results for ARA-290 in SFN.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:04:01.194Z","link_status":"ok","quote_status":"unverified","prev":"287ea93f24ad80a98c1a6981c982b765588f7c48994ec33fd5c3e8387558baaa","hash":"35ebbfb966395203096ee182e44cf5b9b3e5d63a703fd8e9db0c47a4e3ba1d37"},{"id":"s6","type":"pubmed","url":"https://www.sciencedirect.com/science/article/abs/pii/S0006899306022955","title":"Semax, an analog of ACTH(4-7)-Derived Heptapeptide","quote":"We suggest that Semax affects cognitive brain functions by modulating the expression and the activation of the hippocampal BDNF/trkB system.","summary":"Mechanistic study on semax and BDNF.","claim_ids":[],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:04:01.194Z","link_status":"http_403","quote_status":"unverified","prev":"35ebbfb966395203096ee182e44cf5b9b3e5d63a703fd8e9db0c47a4e3ba1d37","hash":"5f3ccbd95070f40d60c205628622c06cdf683ecc7725d45ec18d274f71a5b27f"},{"id":"s7","type":"pubmed","url":"https://journals.lww.com/painrpts/fulltext/2016/08000/targeting_the_innate_repair_receptor_to_treat.2.aspx","title":"Targeting the innate repair receptor to treat neuropathy","quote":"These experimental and clinical studies show that ARA290 effectively reprograms a proinflammatory, tissue-damaging milieu into one of healing and tissue repair.","summary":"Review of ARA-290 mechanism and trials.","claim_ids":[],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:04:01.194Z","link_status":"ok","quote_status":"verified","prev":"5f3ccbd95070f40d60c205628622c06cdf683ecc7725d45ec18d274f71a5b27f","hash":"ede960b1e41b4501fa900184d854693782fa0988873c293180bd30cc6b0ade8d"}]}