{"slug":"semax-corticosteroids","verification":{"valid":true,"entries":3,"head":"b8e133c63cd4f99c7ab715ad5e770250033acdd043a5c3f2a1c4499e6ca81ec6"},"count":3,"sources":[{"id":"s1","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/29798983/","title":"The efficacy of semax in the treatment of patients at different stages of ischemic stroke","quote":"Administration of semax, regardless of the timing of rehabilitation, increased BDNF plasma levels which remained high during the whole study period.","summary":"Human trial of 110 stroke patients showing Semax raises and sustains plasma BDNF with functional correlations.","claim_ids":["c1","c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:13:53.226Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"e07d6e198c02d047b84ecfff9474985f7a66559a5be24c975e03ca98332f1bd2"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/16814837/","title":"Semax, an analog of ACTH(4-10), regulates BDNF and trkB expression in the rat hippocampus","quote":"a single application of Semax (50 μg/kg body weight) results in a maximal 1.4-fold increase of BDNF protein levels accompanying with 1.6-fold increase of trkB tyrosine phosphorylation levels","summary":"Rat study demonstrating Semax effects on hippocampal BDNF/trkB system.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:13:53.226Z","link_status":"ok","quote_status":"unverified","prev":"e07d6e198c02d047b84ecfff9474985f7a66559a5be24c975e03ca98332f1bd2","hash":"7244a1335ed9b57ea570573dddcb2506ddf0c4c7cb7d96aa59db66f75cc3e4ad"},{"id":"s3","type":"medical","url":"https://www.ncbi.nlm.nih.gov/books/NBK531462/","title":"Corticosteroid Adverse Effects - StatPearls","quote":"Corticosteroids constitute a double-edged sword - significant benefit with a low incidence of adverse effects can be expected if used in proper dosage and for appropriate duration.","summary":"Clinical review detailing benefits and tissue-related adverse effects of corticosteroids.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:13:53.226Z","link_status":"ok","quote_status":"unverified","prev":"7244a1335ed9b57ea570573dddcb2506ddf0c4c7cb7d96aa59db66f75cc3e4ad","hash":"b8e133c63cd4f99c7ab715ad5e770250033acdd043a5c3f2a1c4499e6ca81ec6"}]}