{"slug":"semax-cognition","verification":{"valid":true,"entries":5,"head":"c52b7c5fa6d90b2ca4791b93ec98b48f94f713d3c2f39b68348c51b978ea933e"},"count":5,"sources":[{"id":"s1","type":"review","url":"https://www.alzdiscovery.org/uploads/cognitive_vitality_media/Semax-Cognitive-Vitality-For-Researchers.pdf","title":"Semax Cognitive Vitality For Researchers","quote":"In one pilot study in 24 healthy subjects, intranasal 1% semax solution (total dose 1.2 mg) increased resting fMRI signal in the default mode network rostral subcomponent relative to placebo (Lebedeva et al, 2018).","summary":"Reviews human and preclinical evidence on Semax for cognition.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:13:53.227Z","link_status":"ok","quote_status":"unverified","prev":"genesis","hash":"8ad8ce23e624503ac43850952d18db68d823c95c5fc3958a750cb56fb9250767"},{"id":"s2","type":"review","url":"https://www.peptides.org/semax-benefits/","title":"Semax Benefits","quote":"A single administration of intranasal Semax at a dose of 1mg (about 16mcg/kg of body weight) resulted in a 71% memory test accuracy vs. an average of 41% observed in controls.","summary":"Summarizes human cognitive performance study in fatigued subjects.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:13:53.227Z","link_status":"timeout","quote_status":"unverified","prev":"8ad8ce23e624503ac43850952d18db68d823c95c5fc3958a750cb56fb9250767","hash":"ec2e2bb9f5798c9989cc6b1e0e7eb5f1fccc37a9a22a9d815a92e14ecbe3da96"},{"id":"s3","type":"review","url":"https://drlewis.com/semax-for-focus-mood/","title":"Semax for Focus and Mood","quote":"In a clinical trial involving 110 stroke patients, intranasal Semax administered as two 10-day courses at 6,000 µg/day produced measurable increases in plasma BDNF levels.","summary":"Covers stroke patient BDNF and recovery data.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:13:53.227Z","link_status":"ok","quote_status":"unverified","prev":"ec2e2bb9f5798c9989cc6b1e0e7eb5f1fccc37a9a22a9d815a92e14ecbe3da96","hash":"25bf0dd16ab01e0664a32e0399bbd4f2bbd8fe56a127b027993751f16edae2b8"},{"id":"s4","type":"pubmed","url":"https://www.sciencedirect.com/science/article/abs/pii/S0006899306022955","title":"Semax regulates BDNF and trkB expression in the rat hippocampus","quote":"a single application of Semax (50 μg/kg body weight) results in a maximal 1.4-fold increase of BDNF protein levels... Semax-treated animals showed a distinct increase in the number of conditioned avoidance reactions.","summary":"Key rat study on BDNF upregulation and behavioral outcome.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:13:53.227Z","link_status":"http_403","quote_status":"unverified","prev":"25bf0dd16ab01e0664a32e0399bbd4f2bbd8fe56a127b027993751f16edae2b8","hash":"146af19ffbe95d70219f383e5bdc37691a2d5cfa1feddcaef22526677039eba2"},{"id":"s5","type":"reddit","url":"https://www.reddit.com/r/Nootropics/comments/14dhhr9/long_term_effects_of_semax_experiences/","title":"Long term effects of Semax? Experiences?","quote":"I mean that got me into this world because I personally found it profound in my mental state making me less depressed, cleared up brain fog, short term memory seemed markedly better.","summary":"Collection of user reports on cognitive and mood effects.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:13:53.227Z","link_status":"ok","quote_status":"unverified","prev":"146af19ffbe95d70219f383e5bdc37691a2d5cfa1feddcaef22526677039eba2","hash":"c52b7c5fa6d90b2ca4791b93ec98b48f94f713d3c2f39b68348c51b978ea933e"}]}