{"slug":"semaglutide-benzodiazepines","verification":{"valid":true,"entries":5,"head":"9d1c26cd3c73bbf2a954c5d700bbf767e57bcd2cb891c3f59d4aca4c2e102435"},"count":5,"sources":[{"id":"s1","type":"medical","url":"https://www.drugs.com/drug-interactions/diazepam-with-semaglutide-862-0-3878-0.html","title":"Diazepam + Semaglutide interaction","quote":"Semaglutide may affect the absorption of oral medications, as it can delay the emptying of stomach content into the intestines.","summary":"Moderate interaction due to delayed gastric emptying affecting oral benzodiazepine absorption.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:32:10.118Z","link_status":"http_403","quote_status":"unverified","prev":"genesis","hash":"ed28a6a05d9363ed9aebc0b8950c59da2c2231fe5d0b04e26b6a9c6befb0d221"},{"id":"s2","type":"pubmed","url":"https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2822453","title":"Disproportionality Analysis From World Health Organization Global Database","quote":"Significant disproportionality was detected only for semaglutide-associated suicidal ideation (ROR, 1.45; 95% CI, 1.18-1.77... which remained significant in patients with coreported use of... benzodiazepines (ROR, 4.07...","summary":"Pharmacovigilance signal analysis from WHO database on semaglutide and psychiatric reports.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:32:10.118Z","link_status":"http_403","quote_status":"unverified","prev":"ed28a6a05d9363ed9aebc0b8950c59da2c2231fe5d0b04e26b6a9c6befb0d221","hash":"4c6c99620001cc00cd51a4731dd07e726d27ac553b6b73374f0430ae30b1b366"},{"id":"s3","type":"news","url":"https://www.fda.gov/drugs/drug-safety-communications/update-fdas-ongoing-evaluation-reports-suicidal-thoughts-or-actions-patients-taking-certain-type","title":"FDA update on GLP-1 receptor agonists and suicidal thoughts","quote":"Our preliminary evaluation has not found evidence that use of these medicines causes suicidal thoughts or actions.","summary":"FDA statement on lack of causal link.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:32:10.118Z","link_status":"ok","quote_status":"verified","prev":"4c6c99620001cc00cd51a4731dd07e726d27ac553b6b73374f0430ae30b1b366","hash":"9eb71c2a111c0395cad0405794645c97c94788b1343b2111546e97e5e469350a"},{"id":"s4","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/39366019/","title":"Semaglutide exposure and its association with adverse spine surgery outcomes","quote":"the likelihood of undergoing additional lumbar fusion surgery within 1 year post-TLIF was significantly higher in the semaglutide-exposed group... (OR 11.79, 95% CI 8.17-17.33)","summary":"Retrospective human cohort study on semaglutide and lumbar fusion re-operation rates.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:32:10.118Z","link_status":"ok","quote_status":"unverified","prev":"9eb71c2a111c0395cad0405794645c97c94788b1343b2111546e97e5e469350a","hash":"b44e84d87ec89baa45fe6c557a83e6b19b57302b75beffa0cf4a551391ee0b1a"},{"id":"s5","type":"reddit","url":"https://www.reddit.com/r/benzorecovery/comments/1ij8a02/glp1s_benzo_recovery/","title":"GLP-1s & Benzo Recovery thread","quote":"Semaglutide worked really well for me mentally.","summary":"User anecdote from benzodiazepine-recovery subreddit.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:32:10.118Z","link_status":"ok","quote_status":"unverified","prev":"b44e84d87ec89baa45fe6c557a83e6b19b57302b75beffa0cf4a551391ee0b1a","hash":"9d1c26cd3c73bbf2a954c5d700bbf767e57bcd2cb891c3f59d4aca4c2e102435"}]}