{"slug":"selank-ppis","verification":{"valid":true,"entries":4,"head":"4be18f09fba9cb074fa23150de606995474787b40a5d21e9df1d4b26d4e503b2"},"count":4,"sources":[{"id":"s1","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/18454096/","title":"Efficacy and possible mechanisms of action of a new peptide anxiolytic selank in the therapy of generalized anxiety disorders and neurasthenia","quote":"The effect of selank (30 patients) was compared to that of medazepam (32 patients).","summary":"2008 Russian trial showing comparable anxiolytic efficacy.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:37:01.018Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"401042efea6cdccedf6f38d6aa5fcbdaed270b6f5c784549b743c8403fb83e84"},{"id":"s2","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4757669/","title":"Selank Administration Affects the Expression of Some Genes Involved in GABAergic, Serotonergic and Noradrenergic Neurotransmission","quote":"This suggests that the molecular mechanism of action of Selank arises from its ability to affect GABA receptors.","summary":"Preclinical gene expression data on GABA modulation.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:37:01.018Z","link_status":"ok","quote_status":"verified","prev":"401042efea6cdccedf6f38d6aa5fcbdaed270b6f5c784549b743c8403fb83e84","hash":"55aa3fd6b14f53e0582a5e86c9ea0c1fc6e7ae69bdbaadb1ec4eb2195ffe43f0"},{"id":"s3","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10248387/","title":"Adverse Effects Associated with Long-Term Use of Proton Pump Inhibitors","quote":"The long-term use of PPIs is associated with some serious and rare adverse effects including renal diseases (anemia, vitamin B12 deficiency, hypocalcemia)","summary":"Review of PPI long-term risks.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:37:01.018Z","link_status":"ok","quote_status":"unverified","prev":"55aa3fd6b14f53e0582a5e86c9ea0c1fc6e7ae69bdbaadb1ec4eb2195ffe43f0","hash":"af8c052cdbb717fc7ac172acfb9d64e4045f734cac6de89bed98b4a67d229e41"},{"id":"s4","type":"reddit","url":"https://www.reddit.com/r/Anxiety/comments/1nf7y8w/experiences_with_selank/","title":"Experiences with Selank","quote":"my general anxiety decreased a lot, no adverse effects.","summary":"User reports of anxiety reduction.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:37:01.018Z","link_status":"ok","quote_status":"unverified","prev":"af8c052cdbb717fc7ac172acfb9d64e4045f734cac6de89bed98b4a67d229e41","hash":"4be18f09fba9cb074fa23150de606995474787b40a5d21e9df1d4b26d4e503b2"}]}