{"slug":"retatrutide-ppis","verification":{"valid":true,"entries":3,"head":"ecb68ab41cbbe62aa48ca4604d3609bc8875b7af7440800f5155fcf0027fda26"},"count":3,"sources":[{"id":"s1","type":"pubmed","url":"https://www.nejm.org/doi/full/10.1056/NEJMoa2301972","title":"Triple–Hormone-Receptor Agonist Retatrutide for Obesity","quote":"At 48 weeks, the least-squares mean percentage change in the retatrutide groups was −8.7% in the 1-mg group, −17.1% in the combined 4-mg group, −22.8% in the combined 8-mg group, and −24.2% in the 12-mg group, as compared with −2.1% in the placebo group.","summary":"Phase 2 RCT results showing dose-dependent weight loss with retatrutide.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:53:01.570Z","link_status":"http_403","quote_status":"unverified","prev":"genesis","hash":"023b023cb614db520180ebf4e78c5d283079d9c065a61399f952d94c3542a028"},{"id":"s2","type":"news","url":"https://www.prnewswire.com/news-releases/lillys-triple-agonist-retatrutide-delivered-powerful-weight-loss-in-pivotal-phase-3-obesity-trial-302778859.html","title":"Lilly's triple agonist, retatrutide, delivered powerful weight loss in pivotal phase 3 obesity trial","quote":"participants taking retatrutide 9 mg and 12 mg lost an average of 64.4 lbs (25.9%) and 70.3 lbs (28.3%), respectively.","summary":"Phase 3 topline weight loss percentages.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:53:01.570Z","link_status":"ok","quote_status":"verified","prev":"023b023cb614db520180ebf4e78c5d283079d9c065a61399f952d94c3542a028","hash":"987d8f52c309e5c1087a946af2a778da4f24fd8759007691fffbbb5efac68583"},{"id":"s3","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12456669/","title":"A Systematic Review of Long-Term Use of Proton Pump Inhibitors","quote":"Results showed a 12-18% reduction in serum vitamin B12 over 12 months of PPI use.","summary":"Observational findings on B12 changes with PPIs.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:53:01.570Z","link_status":"ok","quote_status":"verified","prev":"987d8f52c309e5c1087a946af2a778da4f24fd8759007691fffbbb5efac68583","hash":"ecb68ab41cbbe62aa48ca4604d3609bc8875b7af7440800f5155fcf0027fda26"}]}