{"slug":"retatrutide-gut","verification":{"valid":true,"entries":3,"head":"a6d0a8ef1bbfe608480f33ce66cab8ac514e6931e0a13a056fe8be697c431457"},"count":3,"sources":[{"id":"s9","type":"pubmed","url":"https://www.nejm.org/doi/full/10.1056/NEJMoa2301972","title":"Triple–Hormone-Receptor Agonist Retatrutide for Obesity","quote":"At 48 weeks, the least-squares mean percentage change in the retatrutide groups was −8.7% in the 1-mg group, −17.1% in the combined 4-mg group, −22.8% in the combined 8-mg group, and −24.2% in the 12-mg group, as compared with −2.1% in the placebo group.","summary":"Phase 2 trial results detailing dose-dependent weight loss and GI adverse events.","claim_ids":["c1","c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:59:03.780Z","link_status":"http_403","quote_status":"unverified","prev":"genesis","hash":"c74d475067414391ce247c2792d113b5ff569cf3b7f154953c014fd6a22f1a89"},{"id":"s10","type":"news","url":"https://investor.lilly.com/news-releases/news-release-details/lillys-triple-agonist-retatrutide-delivered-powerful-weight-loss","title":"Lilly's triple agonist, retatrutide, delivered powerful weight loss","quote":"In TRIUMPH-1, participants on 12 mg retatrutide lost an average of 70.3 lbs (28.3%) over 80 weeks","summary":"Phase 3 topline weight-loss data.","claim_ids":["c2","c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:59:03.780Z","link_status":"ok","quote_status":"verified","prev":"c74d475067414391ce247c2792d113b5ff569cf3b7f154953c014fd6a22f1a89","hash":"bbf208cc52d91f3d33cb3d6704fedb855301edcceeee950c0df9c52f172862cd"},{"id":"s3","type":"pubmed","url":"https://www.nature.com/articles/s41598-019-52103-x","title":"Metabolic and gut microbiome changes following GLP-1 or dual GLP-1/GLP-2 receptor agonist treatment in diet-induced obese mice","quote":"Compared to baseline, DIO mice assumed phylogenetically similar gut bacterial compositional changes following liraglutide and GUB09-145 treatment, characterized by discrete shifts in low-abundant species","summary":"Mouse study on GLP-1 effects on microbiome.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T00:59:03.780Z","link_status":"ok","quote_status":"verified","prev":"bbf208cc52d91f3d33cb3d6704fedb855301edcceeee950c0df9c52f172862cd","hash":"a6d0a8ef1bbfe608480f33ce66cab8ac514e6931e0a13a056fe8be697c431457"}]}