{"slug":"pt-141-skin","verification":{"valid":true,"entries":3,"head":"1566de26be5b19d24a47d8347a7bea223712bf3acf90302e070c32f5387c5b4a"},"count":3,"sources":[{"id":"s0","type":"pubmed","url":"https://www.ncbi.nlm.nih.gov/books/NBK573221/","title":"Bremelanotide - LiverTox® - NCBI Bookshelf","quote":"In the skin, melanocortin receptors activate melanocytes and cause increase in pigmentation. ... Uncommon adverse reactions have included ... local hyperpigmentation.","summary":"Reviews mechanism and side effects including pigmentation changes from clinical data.","claim_ids":["c1","c3","c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T01:08:04.174Z","link_status":"ok","quote_status":"unverified","prev":"genesis","hash":"7363cbda5856b5d482080090cdfbe524ae38872a5ddca08b7b2cac94e910de68"},{"id":"s13","type":"medical","url":"https://www.drugs.com/sfx/bremelanotide-side-effects.html","title":"Bremelanotide Side Effects","quote":"In another clinical study, 38% of patients developed focal hyperpigmentation after receiving this drug daily for 8 days.","summary":"Details hyperpigmentation rates under daily dosing in studies.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T01:08:04.174Z","link_status":"http_403","quote_status":"unverified","prev":"7363cbda5856b5d482080090cdfbe524ae38872a5ddca08b7b2cac94e910de68","hash":"1604e7007ac637721948fb192e99046539faa35dae958d7cd4965402000acca9"},{"id":"s14","type":"reddit","url":"https://www.reddit.com/r/Peptides/comments/1c0ht3j/pt141_whats_the_likelihood_of_permanent_skin/","title":"PT-141 What's the likelihood of permanent skin darkening?","quote":"I started PT-141 2 weeks ago and I noticed my skin getting darker in about a week and now I have hyperpigmentation spots around my temples","summary":"User reports of skin darkening after PT-141 initiation.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T01:08:04.174Z","link_status":"ok","quote_status":"unverified","prev":"1604e7007ac637721948fb192e99046539faa35dae958d7cd4965402000acca9","hash":"1566de26be5b19d24a47d8347a7bea223712bf3acf90302e070c32f5387c5b4a"}]}