{"slug":"pt-141-chemo-neuropathy","verification":{"valid":true,"entries":4,"head":"dfbd76cb8ad6b18dfcac986a41eaceec48918b94bbc240d02fc91a696751a5cf"},"count":4,"sources":[{"id":"s1","type":"review","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC8788464/","title":"Bremelanotide for Treatment of Female Hypoactive Sexual Desire Disorder","quote":"Bremelanotide (PT-141) is a melanocortinergic agent, demonstrated efficacy in improving male and female sexual dysfunction","summary":"Review of bremelanotide mechanism and approval data; no mention of neuropathy applications.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T01:20:03.046Z","link_status":"ok","quote_status":"unverified","prev":"genesis","hash":"0c022fc538f1de8537b8bcc4c7c759a605af2bdb51ff0ece39e8e63e042ba8fb"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/38936970/","title":"Gabapentinoids for chemotherapy-induced peripheral neuropathy","quote":"There is limited evidence to support the use of gabapentinoids in CIPN.","summary":"2024 meta-analysis showing inconsistent results for gabapentinoids in CIPN.","claim_ids":["c2","c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T01:20:03.046Z","link_status":"ok","quote_status":"verified","prev":"0c022fc538f1de8537b8bcc4c7c759a605af2bdb51ff0ece39e8e63e042ba8fb","hash":"990c858f5c6e823bf2e7ee2ad36082f5d9628292f4fce19cc9a55d9df509f172"},{"id":"s3","type":"review","url":"https://go.drugbank.com/drugs/DB11653","title":"Bremelanotide: Uses, Interactions, Mechanism of Action","quote":"Bremelanotide is a 7 amino acid peptide used to treat hypoactive sexual desire disorder in premenopausal women.","summary":"Confirms central melanocortin mechanism.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T01:20:03.046Z","link_status":"http_403","quote_status":"unverified","prev":"990c858f5c6e823bf2e7ee2ad36082f5d9628292f4fce19cc9a55d9df509f172","hash":"0d11326ee0e7f15aa6b9e4afc2c2445c818adfab43dac32efc7cb216b6c02018"},{"id":"s4","type":"reddit","url":"https://www.reddit.com/r/smallfiberneuropathy/comments/v44s3q/effectiveness_of_ara290my_assessment/","title":"Effectiveness of ARA-290...My Assessment","quote":"PT-141 is more sexual/arousal. Wouldn’t recommend that if your focus is on pain reduction.","summary":"User comment distinguishing PT-141 from pain-focused peptides.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T01:20:03.046Z","link_status":"ok","quote_status":"unverified","prev":"0d11326ee0e7f15aa6b9e4afc2c2445c818adfab43dac32efc7cb216b6c02018","hash":"dfbd76cb8ad6b18dfcac986a41eaceec48918b94bbc240d02fc91a696751a5cf"}]}