{"slug":"pt-141-benzodiazepines","verification":{"valid":false,"broken_at":0,"reason":"hash mismatch"},"count":4,"sources":[{"id":"s1","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6819021/","title":"Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder","quote":"Patients taking neuroleptics, lithium, antidepressants, mood stabilizers, benzodiazepines, cognitive enhancers, or γ-aminobutyric acid antagonists within 3 months of screening were also excluded.","summary":"Phase 3 trial exclusion criteria for benzos in bremelanotide HSDD studies.","claim_ids":["c1","c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T01:22:02.862Z","link_status":"ok","quote_status":"verified","prev":"genesis","hash":"b7f416c434c9b3fc9faecf79deda0950e9e92eab0c110ecab405dd861cd4ae54"},{"id":"s14","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/33455598/","title":"The neurobiology of bremelanotide for the treatment of hypoactive sexual desire disorder","quote":"Bremelanotide may affect female sexual desire by activating presynaptic MC4Rs on neurons in the mPOA of the hypothalamus, leading to increased release of DA.","summary":"Preclinical mechanism review on MC4R and dopamine.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T01:22:02.862Z","link_status":"ok","quote_status":"unverified","prev":"b7f416c434c9b3fc9faecf79deda0950e9e92eab0c110ecab405dd861cd4ae54","hash":"8e0b6bd5efdc1469ac4454d30179de2a3c448ee2c74431b3495dfd542b1a738b"},{"id":"s0","type":"reddit","url":"https://www.reddit.com/r/Peptides/comments/7n5guc/deleted_by_user/","title":"[deleted by user] : r/Peptides","quote":"My severe persisting anhedonia posts only began after PT - 141 . And benzos were prescribed for a diff condition entirely.","summary":"User anecdote linking PT-141 to anhedonia with separate benzo mention.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T01:22:02.862Z","link_status":"ok","quote_status":"unverified","prev":"8e0b6bd5efdc1469ac4454d30179de2a3c448ee2c74431b3495dfd542b1a738b","hash":"fe673099526fdf005fa3150777944592b33fb6bb64d8716911630554191d79ff"},{"id":"s5","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6819021/","title":"Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder","quote":"Effect size is important to consider as it indicates the magnitude of the treatment's effect...","summary":"Context on trial design and related pharmacology comparisons.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-06-30T01:22:02.862Z","link_status":"ok","quote_status":"unverified","prev":"fe673099526fdf005fa3150777944592b33fb6bb64d8716911630554191d79ff","hash":"a799c17716cff858dbb74ce25a12652b81eff68de943d68387bb9cdf2446cb7e"}]}