{"slug":"nad-plus-skin","verification":{"valid":true,"entries":5,"head":"424b0a3a05879764c8872f53dfedd853347efc6606084a7e5337195a092b7850"},"count":5,"sources":[{"id":"s1","type":"review","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9512238/","title":"The Role of NAD+ in Regenerative Medicine","quote":"There is also growing evidence that NAD+ decline plays a critical role in the biology of skin aging... Low NAD+ promotes senescence in skin whilst restoration of NAD+ reduces the burden of senescent cells","summary":"Reviews NAD+ role in skin senescence and regeneration from cell/animal data.","claim_ids":["c1"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-07-02T00:05:36.240Z","link_status":"ok","quote_status":"unverified","prev":"genesis","hash":"1b7f186f9b78b6c32c90defdd836bf213f09f86cee9882ba53c66b1331bf62ca"},{"id":"s2","type":"news","url":"https://www.sciencedaily.com/releases/2025/06/250609020625.htm","title":"Common supplement reverses premature aging in landmark human trial","quote":"The double-blind trial revealed that NR not only safely boosted NAD+ levels but also improved cardiovascular health, reduced skin ulcers, and helped protect kidney function in patients.","summary":"Reports NR trial results including skin ulcer reduction.","claim_ids":["c2"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-07-02T00:05:36.240Z","link_status":"ok","quote_status":"verified","prev":"1b7f186f9b78b6c32c90defdd836bf213f09f86cee9882ba53c66b1331bf62ca","hash":"537fb8c4ca054aa40dd67f8db39bdc92aa927f399a9605ed6ffa5436b773d46e"},{"id":"s3","type":"other","url":"https://www.aboutnad.com/blogs/studies/nicotinamide-mononucleotide-and-nicotinamide-riboside-protect-against-skin-aging-preclinical-findings","title":"NMN & NAD for Anti-Aging Just Changed","quote":"In human skin fibroblasts subjected to oxidative and photo-aging stress, nicotinamide mononucleotide (NMN) markedly increased NAD+ levels, activated sirtuin and autophagy pathways, and improved mitochondrial function... NMN reduced cellular senescence, enhanced cell proliferation, preserved extracellular matrix integrity","summary":"Summarizes preclinical fibroblast study on NMN for skin aging.","claim_ids":["c3"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-07-02T00:05:36.240Z","link_status":"ok","quote_status":"verified","prev":"537fb8c4ca054aa40dd67f8db39bdc92aa927f399a9605ed6ffa5436b773d46e","hash":"633b890a8350300a69760c1035e42838a0130fd373f1ce55a68885912b020eb0"},{"id":"s4","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC7558103/","title":"Clinical Evidence for Targeting NAD Therapeutically","quote":"A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin... NAD: ~125% increase in the skin... MN treatment of photodamaged facial skin increased stratum corneum thickness by 70%","summary":"Details human topical niacin/NAD study results.","claim_ids":["c4"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-07-02T00:05:36.240Z","link_status":"ok","quote_status":"unverified","prev":"633b890a8350300a69760c1035e42838a0130fd373f1ce55a68885912b020eb0","hash":"783847a1f29789612f0472bdb5bbfe26cb01f70ec555015ad18105c3b4dd7bda"},{"id":"s5","type":"reddit","url":"https://www.reddit.com/r/SkincareAddiction/comments/1m4keut/antiaging_what_are_peoples_experience_with_nmn/","title":"[Anti-Aging] What are people's experience with NMN?","quote":"I’ve noticed my skin is doing better, I still have no wrinkles at 50... The Good: I noticed that my skin seems softer...","summary":"Collects user anecdotes on NMN skin effects.","claim_ids":["c5"],"found_by":"grok/grok-4.3","extra":{},"accessed_at":"2026-07-02T00:05:36.240Z","link_status":"ok","quote_status":"unverified","prev":"783847a1f29789612f0472bdb5bbfe26cb01f70ec555015ad18105c3b4dd7bda","hash":"424b0a3a05879764c8872f53dfedd853347efc6606084a7e5337195a092b7850"}]}