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Per-claim provenance."}],"not_medical_advice":true},"slug":"mots-c","title":"mots c","register":"standard","tags":[],"updated_at":"2026-07-17T02:40:30.235Z","body_excerpt":"## Overview\nEvidence is being populated by Grok web search.","ranking":"safety-first (interaction_risk/limitations), then quote-gated effective_weight","claims":[],"sources":[{"id":"s1","type":"clinical_trial","url":"https://clinicaltrials.gov/study/NCT07505745","title":"MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity (MOTS-MET)","quote":"This Phase 2a study evaluates whether 12 weeks of treatment with investigational MOTS-c improves insulin sensitivity compared with placebo in adults with prediabetes and overweight/obesity.","summary":"Ongoing Phase 2a randomized double-blind placebo-controlled trial started in 2026 testing MOTS-c for insulin sensitivity in prediabetes and 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