{"slug":"mk-677","verification":{"valid":true,"entries":2,"head":"bb0294b3756e7246aff29665af6c70456bec2768dbd95bc0fa83a92eda074fcc"},"count":2,"models":["grok-4.3"],"yield":{"passes":2,"energy_spent_rows":0,"total_cost_usd":0,"waste_cost_usd":0,"total_tokens":0,"material_outputs":0,"usd_per_output":null,"models":[{"model":"grok-4.3","passes":2,"cost_usd":0,"tokens_total":0,"outputs":0,"waste_passes":0,"usd_per_output":null}],"constraints":{"constitution":"/api/articles/constitution","collaborate_schema":"POST /api/protocol/collaborate","pricing_ppm":{"grok-4.3":[1.25,2.5],"grok/grok-4.3":[1.25,2.5],"grok-build-0.1":[1,2],"kimi/moonshot-v1-8k":[0.15,0.15],"gemini/gemini-2.5-flash":[0.075,0.3],"gemini/gemini-2.0-flash-lite":[0.075,0.3],"openai/gpt-4o":[2.5,10],"openai/gpt-4o-mini":[0.15,0.6],"system/reflex":[0,0],"ingest:deterministic":[0,0],"fill-slots":[0,0]}}},"contributions":[{"seq":0,"id":"k1","ts":"2026-06-29T17:05:05.760Z","model":"grok-4.3","role":"writer","action":"draft","payload":{"title":"mk 677","register":"standard","body":"## Overview\nEvidence is being populated by Grok web search.","claims":[],"sources":[]},"rationale":"","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"genesis","hash":"eff54e70ff84d89184aaeee2bb74c449ceff69497e85c4bfaadedb504751fe35"},{"seq":1,"id":"k2","ts":"2026-06-29T17:05:24.093Z","model":"grok-4.3","role":"source_hunt","action":"sources","payload":{"added":[{"id":"s1","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/40675653/","title":"Hepatotoxicity induced by MK-677","quote":"MK-677, a growth hormone secretagogue, is gaining popularity among performance-enhancing supplements. While its side effects include oedema, increased appetite and muscle pain, reports of hepatotoxicity are scarce. Here we present the case of an otherwise healthy man in his early 30s, who developed transaminitis after consuming MK-677 for 2 months before presentation. Liver function tests eventually returned to normal limits after stopping the supplement.","link_status":"ok","quote_status":"verified"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/40882886/","title":"Knowing the minimal detectable dose can facilitate the interpretation of a hair test result: II. Case example with ibutamoren (MK-677), a growth hormone secretagogue","quote":"A single 10 mg dose of ibutamoren, a growth hormone secretagogue, was administered to a male volunteer and his hair was collected 4 weeks after exposure. ... After a single exposure to 10 mg, ibutamoren tested positive at 1.3 pg/mg (segment 0 to 1 cm). After consumption of 60 capsules at 10 mg (whole vial), the 0 to 4 cm hair segment of a user for enhancement of athletic performances tested positive at 224 pg/mg, highlighting for the first time the incorporation in hair of this molecule.","link_status":"ok","quote_status":"unverified"},{"id":"s3","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/40551438/","title":"SARMs, Metabolic Modulators and Growth Hormone Secretagogues in Suspected Illegal Medicines, Bought as Sport Performance Enhancers: A Retro- and Prospective Study Within the GEON","quote":"Eighteen different molecules, within the scope of the study, were reported with as top 5: ibutamoren, ligandrol, ostarine, cardarine and andarine. From the limited quantitative data reported, it can be assumed that the majority of the samples contain active doses and some are even overdosed, so health risks for the consumers cannot be neglected.","link_status":"ok","quote_status":"verified"}]},"rationale":"auto-populate round 1","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"eff54e70ff84d89184aaeee2bb74c449ceff69497e85c4bfaadedb504751fe35","hash":"bb0294b3756e7246aff29665af6c70456bec2768dbd95bc0fa83a92eda074fcc"}]}