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During the last 25 years, this compound has been extensively studied using in vitro, in vivo, and in silico methods. The results of these studies indicate significant geroprotective and neuroendocrine effects of Epitalone, resulting from its antioxidant, neuro-protective, and antimutagenic effects, originating from both specific and nonspecific mechanisms.","summary":"2025 review summarizing 25 years of Epitalon research showing geroprotective, antioxidant, neuroprotective effects via in vitro/in vivo studies; notes limited physico-chemical data.","claim_ids":["c1"],"link_status":"ok","quote_status":"verified","hash":"9a9574559d7d8fd6c39094404f914bfff9e2ea377f14b7a0fd5d7d8c8cf63735"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/40908429/","title":"Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity","quote":"Epitalon, a naturally occurring tetrapeptide, is known for its anti-aging effects on mammalian cells. 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