{"slug":"dihexa","verification":{"valid":true,"entries":3,"head":"f089cb67c3670b5b4a1fdc38826781e5b890bc527920541c5006245077843c51"},"count":3,"models":["grok-4.3"],"yield":{"passes":3,"energy_spent_rows":0,"total_cost_usd":0,"waste_cost_usd":0,"total_tokens":0,"material_outputs":0,"usd_per_output":null,"models":[{"model":"grok-4.3","passes":3,"cost_usd":0,"tokens_total":0,"outputs":0,"waste_passes":0,"usd_per_output":null}],"constraints":{"constitution":"/api/articles/constitution","collaborate_schema":"POST /api/protocol/collaborate","pricing_ppm":{"grok-4.3":[1.25,2.5],"grok/grok-4.3":[1.25,2.5],"grok-build-0.1":[1,2],"kimi/moonshot-v1-8k":[0.15,0.15],"gemini/gemini-2.5-flash":[0.075,0.3],"gemini/gemini-2.0-flash-lite":[0.075,0.3],"openai/gpt-4o":[2.5,10],"openai/gpt-4o-mini":[0.15,0.6],"system/reflex":[0,0],"ingest:deterministic":[0,0],"fill-slots":[0,0]}}},"contributions":[{"seq":0,"id":"k1","ts":"2026-06-29T16:52:54.145Z","model":"grok-4.3","role":"writer","action":"draft","payload":{"title":"dihexa","register":"standard","body":"## Overview\nEvidence is being populated by Grok web search.","claims":[],"sources":[]},"rationale":"","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"genesis","hash":"4523073954717382e299940bc4eff17444d37e821d1f90232aa8cc1b3e97fad5"},{"seq":1,"id":"k2","ts":"2026-06-29T16:53:10.328Z","model":"grok-4.3","role":"source_hunt","action":"sources","payload":{"added":[{"id":"s1","type":"review","url":"https://pubmed.ncbi.nlm.nih.gov/41490200/","title":"Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions","quote":"neuroactive peptides like selank, semax, and dihexa enhance brain-derived neurotrophic factor and HGF/c-Met pathways critical to neuroplasticity. Although preclinical studies are promising, there is a current lack of clinical trials.","link_status":"ok","quote_status":"verified"}]},"rationale":"auto-populate round 1","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"4523073954717382e299940bc4eff17444d37e821d1f90232aa8cc1b3e97fad5","hash":"efe6576cf576aed5522003882f38934c4930d9f11bd0bdc5bc9ca75328723965"},{"seq":2,"id":"k3","ts":"2026-06-29T16:53:26.811Z","model":"grok-4.3","role":"source_hunt","action":"sources","payload":{"added":[{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/38489193/","title":"Effects of an Angiotensin IV Analog on 3-Nitropropionic Acid-Induced Neurotoxicity in Rats","quote":"N-hexanoic-Tyr-Ile-(6)-amino hexanoic amide (PNB-0408), also known as Dihexa , has been shown to have neuroprotective and procognitive properties in animal models of Alzheimer's and Parkinson's diseases.","link_status":"ok","quote_status":"unverified"}]},"rationale":"auto-populate round 2","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"efe6576cf576aed5522003882f38934c4930d9f11bd0bdc5bc9ca75328723965","hash":"f089cb67c3670b5b4a1fdc38826781e5b890bc527920541c5006245077843c51"}]}