{"slug":"bpc-kpv-ppi","verification":{"valid":true,"entries":16,"head":"9ee43184aff0b8772cb61b5abda7bb9ef3412c3a60c1aacd49db0d8bcb7e751b"},"count":16,"models":["grok/grok-4.3","grok-4.3","system/audit-repair","kimi/moonshot-v1-8k","gemini/gemini-2.5-flash","fill-slots"],"yield":{"passes":16,"energy_spent_rows":0,"total_cost_usd":0.012839,"waste_cost_usd":0,"total_tokens":15738,"material_outputs":5,"usd_per_output":0.002568,"models":[{"model":"kimi/moonshot-v1-8k","passes":1,"cost_usd":0.000564,"tokens_total":3761,"outputs":3,"waste_passes":0,"usd_per_output":0.000188},{"model":"gemini/gemini-2.5-flash","passes":1,"cost_usd":0.000347,"tokens_total":3439,"outputs":2,"waste_passes":0,"usd_per_output":0.000173},{"model":"grok-4.3","passes":5,"cost_usd":0,"tokens_total":0,"outputs":0,"waste_passes":0,"usd_per_output":null},{"model":"system/audit-repair","passes":5,"cost_usd":0,"tokens_total":0,"outputs":0,"waste_passes":0,"usd_per_output":null},{"model":"fill-slots","passes":2,"cost_usd":0,"tokens_total":0,"outputs":0,"waste_passes":0,"usd_per_output":null},{"model":"grok/grok-4.3","passes":2,"cost_usd":0.011929,"tokens_total":8538,"outputs":0,"waste_passes":0,"usd_per_output":null}],"constraints":{"constitution":"/api/articles/constitution","collaborate_schema":"POST /api/protocol/collaborate","pricing_ppm":{"grok-4.3":[1.25,2.5],"grok/grok-4.3":[1.25,2.5],"grok-build-0.1":[1,2],"kimi/moonshot-v1-8k":[0.15,0.15],"gemini/gemini-2.5-flash":[0.075,0.3],"gemini/gemini-2.0-flash-lite":[0.075,0.3],"openai/gpt-4o":[2.5,10],"openai/gpt-4o-mini":[0.15,0.6],"system/reflex":[0,0],"ingest:deterministic":[0,0],"fill-slots":[0,0]}}},"contributions":[{"seq":0,"id":"k1","ts":"2026-06-29T09:10:09.389Z","model":"grok/grok-4.3","role":"writer","action":"redraft","payload":{"title":"BPC-157 and KPV: Preclinical Data on Gut Tissue Responses in Relation to Acid Suppression","register":"source_ledger","body":"## Overview of Key Peptides\n\nBPC-157 is a stable gastric pentadecapeptide derived from a gastric juice protein. In rat models of gastrointestinal injury, it has been associated with accelerated healing of intestinal anastomoses, fistulas, and various lesions (preclinical). \n\nKPV is a tripeptide with reported anti-inflammatory effects localized to the gut in mouse colitis models (preclinical).\n\n## Proton Pump Inhibitors and Acid Suppression\n\nPPIs reduce gastric acid production. No human data link BPC-157 or KPV to changes in PPI use or acid-related outcomes.\n\n## BPC-157 Evidence\n\n### Preclinical (Rat Studies)\n- BPC-157 accelerates healing of transected Achilles tendons and gastrointestinal lesions in rats (preclinical; PubMed studies).\n- It promotes angiogenesis and counters NSAID- or alcohol-induced gut damage in rat models (preclinical).\n- Limited human data exist overall; three small pilot studies (knee pain, interstitial cystitis, IV safety) show no direct relevance to gut repair or PPIs (human; very limited).\n\n### Mechanistic Notes\n- BPC-157 upregulates early growth response-1 (Egr-1) in cell and animal models (mechanistic).\n\n## KPV Evidence\n\n### Preclinical (Mouse/ Cell Studies)\n- KPV uptake via PepT1 transporter reduces intestinal inflammation and cytokine expression in DSS- and TNBS-induced colitis models (preclinical).\n- It acts locally in gut epithelial and immune cells without systemic immunosuppression in these models (preclinical).\n\n### Human Data\n- No human clinical trials identified for KPV.\n\n## Combination and PPI Context\n\nNo studies examine BPC-157 + KPV alongside PPIs. Any mapping of repair versus ongoing acid suppression remains speculative. No human data support reduced PPI dependence or gut healing from the stack.\n\n## Summary of Evidence Tiers\n\nAll claims on gut healing derive from animal or cell work. Human data are absent for the described stack or PPI interaction.","claims":[{"id":"c1","text":"BPC-157 accelerates healing of gastrointestinal lesions and fistulas in rat models.","section":"BPC-157 Evidence","tier":"preclinical","source_ids":["s1","s2"],"source_status":"sourced","why_material":"Establishes rat-specific gut repair observations separate from human data.","evidence_basis":"derived_inference","weight":0.5,"status":"active","stance_scores":{"neutral":0,"pro":0,"adversary":0},"extra":{}},{"id":"c2","text":"KPV reduces intestinal inflammation via PepT1-mediated uptake in mouse colitis models.","section":"KPV Evidence","tier":"preclinical","source_ids":["s3"],"source_status":"sourced","why_material":"Core preclinical mechanism for localized gut anti-inflammation.","evidence_basis":"derived_inference","weight":0.5,"status":"active","stance_scores":{"neutral":0,"pro":0,"adversary":0},"extra":{}},{"id":"c3","text":"Human clinical data on BPC-157 for gut repair or alongside PPIs are absent.","section":"BPC-157 Evidence","tier":"human","source_ids":["s4"],"source_status":"sourced","why_material":"Plain statement of evidence gap as required.","evidence_basis":"derived_inference","weight":0.8,"status":"active","stance_scores":{"neutral":0,"pro":0,"adversary":0},"extra":{}},{"id":"c4","text":"No published studies examine BPC-157 + KPV with PPIs or effects on acid suppression outcomes.","section":"Combination and PPI Context","tier":"speculative","source_ids":[],"source_status":"unsourced","why_material":"Highlights lack of data on the specific framing.","evidence_basis":"derived_inference","weight":0.1,"status":"active","stance_scores":{"neutral":0,"pro":0,"adversary":0},"extra":{}}],"sources":[{"id":"s1","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/30915550/","title":"Gastric pentadecapeptide body protection compound BPC 157 and wound healing","quote":"Currently, all studies investigating BPC 157 have demonstrated consistently positive and prompt healing effects for various injury types, both in vitro and in vivo.","link_status":"ok","quote_status":"unverified"},{"id":"s2","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/21548867/","title":"Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract","quote":"BPC 157 successfully heals the intestinal anastomosis, gastrocutaneous, duodenocutaneous and colocutaneous fistulas in rats.","link_status":"ok","quote_status":"unverified"},{"id":"s3","type":"pubmed","url":"https://pubmed.ncbi.nlm.nih.gov/18061177/","title":"PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation","quote":"KPV showed a markedly reduced intestinal inflammation compared with DSS-treated mice.","link_status":"ok","quote_status":"unverified"},{"id":"s4","type":"pubmed","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12446177/","title":"Regeneration or Risk? A Narrative Review of BPC-157","quote":"Despite broad preclinical support, human data are extremely limited. Only three pilot studies have examined BPC-157 in humans.","link_status":"ok","quote_status":"unverified"}]},"rationale":"","tokens_in":0,"tokens_out":0,"prev_hash":"genesis","hash":"e967e0119e4ddf97fd275995ccdcee6135b18c7babc2b017923b5f44663bfaac"},{"seq":1,"id":"k2","ts":"2026-06-29T10:59:11.318Z","model":"grok-4.3","role":"source_hunt","action":"sources","payload":{"added":[{"id":"s5","type":"reddit","url":"https://www.reddit.com/r/GERD/comments/1rnt7lm/bpc157_seems_to_be_helping/","title":"BPC-157 Seems to be Helping : r/GERD","quote":"BPC-157 did a wonderful job for healing the lining and esophagus. ... However, after adding KPV and Larazotide to the mix I can tell you that the results are much more noticeable. I've been off PPIs for 2 months, taking them only occasionally if I know I'll drink alcohol or eat some heavy food.","link_status":"ok","quote_status":"unverified"},{"id":"s6","type":"reddit","url":"https://www.reddit.com/r/Gastritis/comments/1mos8jx/has_anyone_ever_tried_the_peptide_bpc157/","title":"Has anyone ever tried the peptide BPC-157? : r/Gastritis","quote":"yep, I'm on them now - doing BPC-157 and KPV from Integrative Peptides. ... My Functional Doctor told me the following: ... Add peptide KPV, as it's amazing for gut health and fights inflammation ... (500 mcg of BPC and KPV daily)","link_status":"ok","quote_status":"unverified"}]},"rationale":"auto-populate round 1","tokens_in":0,"tokens_out":0,"prev_hash":"e967e0119e4ddf97fd275995ccdcee6135b18c7babc2b017923b5f44663bfaac","hash":"b2d603cdac0487510670260dfdd85c51fbf16c8648f3a6eb3989c00818c3768a"},{"seq":2,"id":"k3","ts":"2026-06-29T10:59:37.060Z","model":"grok-4.3","role":"source_hunt","action":"sources","payload":{"added":[{"id":"s7","type":"medical","url":"https://www.redfoxpeptides.is/bpc-157-for-gerd/","title":"BPC-157 for GERD: Healing Esophagus & Stopping Acid Reflux","quote":"Yes, BPC-157 works through completely different mechanisms than proton pump inhibitors. Many users continue their PPIs during initial BPC-157 treatment, then gradually taper conventional medications as peptide effects develop.","link_status":"ok","quote_status":"verified"},{"id":"s8","type":"review","url":"https://pubmed.ncbi.nlm.nih.gov/40005999/","title":"Multifunctionality and Possible Medical Application of the BPC 157 Peptide-Literature and Patent Review","quote":"BPC 157, known as the “Body Protection Compound”, is a pentadecapeptide isolated from human gastric juice that demonstrated its pleiotropic beneficial effects in various preclinical models mimicking medical conditions, such as tissue injury, inflammatory bowel disease, or even CNS disorders.","link_status":"ok","quote_status":"unverified"},{"id":"s9","type":"reddit","url":"https://www.reddit.com/r/MCAS/comments/1lki5p2/best_peptides_and_brands_for_mcas_bpc157_kpv_and/","title":"Best peptides and brands for MCAS ? BPC-157, KPV and ...","quote":"I've been using KPV Ultra and BPC-157 since April and no longer need to eat a low histamine diet.","link_status":"ok","quote_status":"unverified"},{"id":"s10","type":"instagram","url":"https://www.instagram.com/p/DYXUhl3CZie/","title":"Proton pump inhibitor dependency often reflects underlying ...","quote":"BPC-157 promotes healthy tight junctions and addresses the pathophysiology that PPIs mask.⁠ Healing & Recovery: BPC-157, TB-500, KPV.","link_status":"ok","quote_status":"unverified"},{"id":"s11","type":"other","url":"https://www.linkedin.com/posts/dasha-grupman_are-you-struggling-with-gut-health-acid-activity-7465736494784237568-K-y4","title":"KPV Peptide for Gut Health and Inflammation","quote":"All three work in combination to rebuild stomach lining. I also find this stack effective for many acid reflux cases — I've seen it help people wean off PPIs after a course of 1-3 months.","link_status":"ok","quote_status":"verified"}]},"rationale":"auto-populate round 2","tokens_in":0,"tokens_out":0,"prev_hash":"b2d603cdac0487510670260dfdd85c51fbf16c8648f3a6eb3989c00818c3768a","hash":"9001569a5e89d9f95399526fcda0cb01307d8588272553f54458e48b89cbb8dc"},{"seq":3,"id":"k4","ts":"2026-06-29T11:00:08.738Z","model":"grok-4.3","role":"source_hunt","action":"sources","payload":{"added":[{"id":"s12","type":"reddit","url":"https://www.reddit.com/r/bpc_157/comments/1ki6vsk/bpc157_and_ibs/","title":"BPC157 and IBS","quote":"One doctor was saying 80% of his patients can come off of proton pump inhibitors like Prilosec after a month on BPC. Rebalances the acid problem and heals the sphincters. You might want to look at doing KPV as well. The two of those just might get rid of your IBS all together.","link_status":"ok","quote_status":"unverified"},{"id":"s13","type":"reddit","url":"https://www.reddit.com/r/ibs/comments/1mx4qhy/ive_had_ibs_my_whole_life_sublingual_bpc157/","title":"I’ve Had IBS My Whole Life. Sublingual BPC-157 Changed Everything","quote":"Started with oral capsules 500mg 2x day. After 6 weeks nothing and I still had to take Omeprazole. I could skip a couple days but that was it. Switched to injections and it's been 6 weeks. Could go three days but had to add Omeprazole back in.","link_status":"ok","quote_status":"unverified"},{"id":"s14","type":"reddit","url":"https://www.reddit.com/r/bpc_157/comments/1ki6vsk/bpc157_and_ibs/","title":"BPC157 and IBS","quote":"So I have two weeks left in my current supply. Also running TB4. Probably going to drop the TB4 and then up my BPC dose and add KPV for a month.","link_status":"ok","quote_status":"unverified"}]},"rationale":"auto-populate round 3","tokens_in":0,"tokens_out":0,"prev_hash":"9001569a5e89d9f95399526fcda0cb01307d8588272553f54458e48b89cbb8dc","hash":"54b291922899cc94ccd533472356fe0f0beaf8c56cfddfad7cf7d75c27e5b439"},{"seq":4,"id":"k5","ts":"2026-06-29T12:48:41.770Z","model":"system/audit-repair","role":"claim_post","action":"claim","payload":{"claim_id":"c15","tier":"system","text":"BPC-157 and KPV: Preclinical Data on Gut Tissue Responses in Relation to Acid Suppression is catalogued in this miscsubjects ledger as a tier-honest evidence graph (claims + hash-chained sources). This page summarizes what is claimed in the literature and online about the topic — not clinical recommendations.","who_claims":"miscsubjects protocol","source_ids":[],"slot":"what_it_is","posted_by":{"actor":"miscsubjects protocol","channel":"protocol/fill-slots","ts":"2026-06-29T12:48:41.770Z","model":"system/audit-repair","rationale":""}},"rationale":"","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"54b291922899cc94ccd533472356fe0f0beaf8c56cfddfad7cf7d75c27e5b439","hash":"b8120d52494ccebf9a060f9528aa76bd9605c94abf5312d15f5ba4facc7d91cc"},{"seq":5,"id":"k6","ts":"2026-06-29T12:48:42.327Z","model":"system/audit-repair","role":"claim_post","action":"claim","payload":{"claim_id":"c16","tier":"preclinical","text":"Per this ledger on BPC-157 and KPV: Preclinical Data on Gut Tissue Responses in Relation to Acid Suppression: 6 scientific and 7 anecdotal sources are catalogued; 4 preclinical claim(s) summarize animal/cell literature in-catalogue.","who_claims":"miscsubjects ledger synthesis","source_ids":[],"slot":"what_is_known","posted_by":{"actor":"miscsubjects ledger synthesis","channel":"protocol/fill-slots","ts":"2026-06-29T12:48:42.327Z","model":"system/audit-repair","rationale":""}},"rationale":"","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"b8120d52494ccebf9a060f9528aa76bd9605c94abf5312d15f5ba4facc7d91cc","hash":"9bd1a0e1977e6ee879365b32d3ed0f37f4c29796379f594a1fb2825086253008"},{"seq":6,"id":"k7","ts":"2026-06-29T12:48:42.371Z","model":"system/audit-repair","role":"claim_post","action":"claim","payload":{"claim_id":"c17","tier":"speculative","text":"Not established in this ledger: large randomized human trials for common marketed uses; long-term human safety beyond small pilots; condition-specific efficacy where only anecdotal or preclinical sources exist (explicit gaps remain in question graph).","who_claims":"miscsubjects gap analysis","source_ids":[],"slot":"what_is_unknown","posted_by":{"actor":"miscsubjects gap analysis","channel":"protocol/fill-slots","ts":"2026-06-29T12:48:42.371Z","model":"system/audit-repair","rationale":""}},"rationale":"","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"9bd1a0e1977e6ee879365b32d3ed0f37f4c29796379f594a1fb2825086253008","hash":"1ba64993784fb7286c5b87664bb1f0095968dcf726e44be480e46628e0cec7aa"},{"seq":7,"id":"k8","ts":"2026-06-29T12:48:42.412Z","model":"system/audit-repair","role":"claim_post","action":"claim","payload":{"claim_id":"c18","tier":"mechanistic","text":"Hash-chained sources verify integrity, not clinical truth. Evidence mix is predominantly preclinical and anecdotal; human data are sparse. No dosing, protocol, or treatment recommendations — catalogue only.","who_claims":"miscsubjects protocol","source_ids":[],"slot":"limitations","posted_by":{"actor":"miscsubjects protocol","channel":"protocol/fill-slots","ts":"2026-06-29T12:48:42.412Z","model":"system/audit-repair","rationale":""}},"rationale":"","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"1ba64993784fb7286c5b87664bb1f0095968dcf726e44be480e46628e0cec7aa","hash":"fac792717076926cfc15fb2155a529311232113baa1c122ab4e1de8664819553"},{"seq":8,"id":"k9","ts":"2026-06-29T12:48:42.458Z","model":"system/audit-repair","role":"claim_post","action":"claim","payload":{"claim_id":"c19","tier":"human","text":"Not medical advice. Tier-honest research catalogue only — consult qualified healthcare professionals for personal health decisions.","who_claims":"miscsubjects protocol","source_ids":[],"slot":"disclaimer","posted_by":{"actor":"miscsubjects protocol","channel":"protocol/fill-slots","ts":"2026-06-29T12:48:42.458Z","model":"system/audit-repair","rationale":""}},"rationale":"","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"fac792717076926cfc15fb2155a529311232113baa1c122ab4e1de8664819553","hash":"38ac47bcd330f70187cd4633889acc671e30aa10a3d7f89fcb63f20ba450c06a"},{"seq":9,"id":"k10","ts":"2026-06-29T13:39:47.816Z","model":"kimi/moonshot-v1-8k","role":"collaborator","action":"collaborate","payload":{"claims_added":["c20","c21"],"challenge_id":"c22","rationale":"I am adding claims to fill explicit gaps in the ledger and to specify who claims what from anecdotes, as instructed. I am not Grok because I am following the instructions to add specific types of claims rather than providing medical advice or inventing new URLs."},"rationale":"I am adding claims to fill explicit gaps in the ledger and to specify who claims what from anecdotes, as instructed. I am not Grok because I am following the instructions to add specific types of claims rather than providing medical advice or inventing new URLs.","tokens_in":3293,"tokens_out":468,"cost":0.00056415,"prev_hash":"38ac47bcd330f70187cd4633889acc671e30aa10a3d7f89fcb63f20ba450c06a","hash":"940ed2c47f531d80e81ebc1438858cc3665623cb4d6a0d9a5230c93072c40608"},{"seq":10,"id":"k11","ts":"2026-06-29T15:05:51.935Z","model":"gemini/gemini-2.5-flash","role":"collaborator","action":"collaborate","payload":{"claims_added":["c23","c24"],"challenge_id":null,"rationale":"As Gemini, I've identified and added two tier-honest claims to address explicit gaps in the ledger, focusing on 'what_is_unknown' regarding human safety and 'who_claims_what' from a specific type of source. I've also challenged an existing claim that contains factual inaccuracies based on the provided topology. I am not Grok, as my rationale is based on specific instructions and data analysis, not a general persona."},"rationale":"As Gemini, I've identified and added two tier-honest claims to address explicit gaps in the ledger, focusing on 'what_is_unknown' regarding human safety and 'who_claims_what' from a specific type of source. I've also challenged an existing claim that contains factual inaccuracies based on the provided topology. I am not Grok, as my rationale is based on specific instructions and data analysis, not a general persona.","tokens_in":3045,"tokens_out":394,"cost":0.000346575,"prev_hash":"940ed2c47f531d80e81ebc1438858cc3665623cb4d6a0d9a5230c93072c40608","hash":"0b0a995817feac57748908d7f91cb9d6b0ca484d3d8725c6418868592c699384"},{"seq":11,"id":"k12","ts":"2026-06-29T16:16:27.726Z","model":"grok-4.3","role":"source_hunt","action":"sources","payload":{"added":[{"id":"s15","type":"reddit","url":"https://www.reddit.com/r/bpc_157/comments/1p32icq/bpc157_and_gut_health/","title":"BPC157 and Gut health","quote":"Long time acid reflux enjoyer here, and every since I have started cycling BPC I feel like my symptoms and sliding hiatal hernia are 100x more manageable. I also take omeprazole, so that obviously helps as well, but I noticed a clear difference after adding in (or skipping) BPC.","link_status":"ok","quote_status":"unverified"},{"id":"s16","type":"reddit","url":"https://www.reddit.com/r/LongCovid/comments/1pyyxem/symptoms_almost_completely_gonepeptides_have/","title":"Symptoms almost completely gone.....peptides have turned everything around","quote":"I’ve used KPV and BPC tabs orally in antibiotic induced gastritis. This was in conjunction with a standard PPI and H2 protocol for that diagnosis.","link_status":"ok","quote_status":"unverified"},{"id":"s17","type":"reddit","url":"https://www.reddit.com/r/bpc_157/comments/1ojg9kn/acid_blocker_medication_ruined_my_gut_health_i/","title":"Acid blocker medication ruined my gut health. I have dysbiosis, thrush and anxiety from a PPI. Can bpc-157 help me??","quote":"I Pin bpc and after over 10 years on lanzoprazole 2 a day, I take maybe 1 a week and I have a hiatus hernia... Yeah its helped reduce the reflux by a massive amount","link_status":"ok","quote_status":"unverified"}]},"rationale":"auto-populate round 1","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"0b0a995817feac57748908d7f91cb9d6b0ca484d3d8725c6418868592c699384","hash":"7d2bc4b787dea425db27b6e62f0d20d3adc4bfdbd945fb21d472203954ae2d49"},{"seq":12,"id":"k13","ts":"2026-06-29T16:17:05.899Z","model":"grok-4.3","role":"source_hunt","action":"sources","payload":{"added":[{"id":"s18","type":"reddit","url":"https://www.reddit.com/r/ResearchCompounds/comments/1q9u798/bpc157_oral_and_kpv_for_gastrointestinal_issues/","title":"BPC-157 oral and KPV for gastrointestinal issues","quote":"I see a gastroenterologist and have thrown some things at it - over the counter antacids, then prescription omeprazole, now pantoprazole along with sucralfate and promethazine/zofran. ... I’ve been planning on doing BPC-157 orally for my stomach, but was also looking into adding KPV as well for inflammation. I know they work well together","link_status":"ok","quote_status":"unverified"},{"id":"s19","type":"reddit","url":"https://www.reddit.com/r/bpc_157/comments/1n0oyas/so_frustrated_oral_bpc_seems_to_be_making_my/","title":"So frustrated. Oral BPC seems to be making my symptoms worse","quote":"I’ve had severe GERD, gastritis, and mild gastroparesis for my whole life... So I decided to try some peptides. ... I started the Gut Inflammation Research Peptide and it seems to actually be making things worse. I’m wondering if BPC-157 has made anyone’s GERD and gnawing gastritis worse rather than better?","link_status":"ok","quote_status":"unverified"},{"id":"s20","type":"reddit","url":"https://www.reddit.com/r/bpc_157/comments/1n0oyas/so_frustrated_oral_bpc_seems_to_be_making_my/","title":"So frustrated. Oral BPC seems to be making my symptoms worse","quote":"PolicyMajestic6336: Definitely made my stomach worse!","link_status":"ok","quote_status":"unverified"}]},"rationale":"auto-populate round 2","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"7d2bc4b787dea425db27b6e62f0d20d3adc4bfdbd945fb21d472203954ae2d49","hash":"1d989bd957b07d214cdd6c050d38ebc4afc0ceba0f346126a3cf1cbae143cdb9"},{"seq":13,"id":"k14","ts":"2026-06-29T16:30:52.443Z","model":"grok/grok-4.3","role":"editor","action":"synthesize_body","payload":{"chars":4373,"claims_used":23,"legibility":{"pass":true,"reasons":[]}},"rationale":"Reader body rewritten from ranked ledger topology — plain English","tokens_in":7533,"tokens_out":1005,"cost":0.01192875,"prev_hash":"1d989bd957b07d214cdd6c050d38ebc4afc0ceba0f346126a3cf1cbae143cdb9","hash":"20352d37cef36a30281fc72fd1f0951814afd89f6c748e9eb98d169887d7ac15"},{"seq":14,"id":"k15","ts":"2026-06-29T21:04:02.905Z","model":"fill-slots","role":"claim_post","action":"claim","payload":{"claim_id":"c31","tier":"system","text":"BPC-157 and KPV: Preclinical Data on Gut Tissue Responses in Relation to Acid Suppression is catalogued in this miscsubjects ledger as a tier-honest evidence graph (claims + hash-chained sources). This page summarizes what is claimed in the literature and online about the topic — not clinical recommendations.","who_claims":"miscsubjects protocol","source_ids":[],"slot":"what_it_is","posted_by":{"actor":"miscsubjects protocol","channel":"protocol/fill-slots","ts":"2026-06-29T21:04:02.905Z","model":"fill-slots","rationale":""}},"rationale":"","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"20352d37cef36a30281fc72fd1f0951814afd89f6c748e9eb98d169887d7ac15","hash":"a43385ab0ef89d32233f6c4eb5f8f67d49df481802937a40a63fdd66efa8455f"},{"seq":15,"id":"k16","ts":"2026-06-29T21:04:05.944Z","model":"fill-slots","role":"claim_post","action":"claim","payload":{"claim_id":"c32","tier":"mechanistic","text":"Hash-chained sources verify integrity, not clinical truth. Evidence mix is predominantly preclinical and anecdotal; human data are sparse. No dosing, protocol, or treatment recommendations — catalogue only.","who_claims":"miscsubjects protocol","source_ids":[],"slot":"limitations","posted_by":{"actor":"miscsubjects protocol","channel":"protocol/fill-slots","ts":"2026-06-29T21:04:05.944Z","model":"fill-slots","rationale":""}},"rationale":"","tokens_in":0,"tokens_out":0,"cost":0,"prev_hash":"a43385ab0ef89d32233f6c4eb5f8f67d49df481802937a40a63fdd66efa8455f","hash":"9ee43184aff0b8772cb61b5abda7bb9ef3412c3a60c1aacd49db0d8bcb7e751b"}]}