{"slug":"bdnf-explained","verification":{"valid":true,"entries":41,"head":"bcf08e528820ea7ad1a92f31fe141ccbe3ebc5052c78642aaf5ee51062aa77cb"},"energy":{"passes":41,"tokens_in":13538,"tokens_out":1706,"tokens_total":15244,"cost_usd":0,"models":{"grok/grok-4.3":2,"grok-4.3":23,"system/audit-repair":9,"kimi/moonshot-v1-8k":1,"gemini/gemini-2.5-flash":1,"repair":2,"fill-slots":2,"owner":1},"head":"bcf08e528820ea7ad1a92f31fe141ccbe3ebc5052c78642aaf5ee51062aa77cb"},"provenance":[{"ts":"2026-06-29T09:33:16.178Z","model":"grok/grok-4.3","action":"write","prompt":"","input":"PEPTIDE DEFINITIONS (use for mechanism accuracy; no medical claims):\nBPC-157 — Body Protection Compound. Derived from gastric juice protein. Builds new blood vessels into damaged tissue locally. 100+ animal/cell studies (tendon, gut, muscle, bone, nerve).\nTB-500 — Synthetic Thymosin Beta-4. Moves repair cells to damage; clears stuck inflammation systemically. Production drops ~60% by age 60.\nARA-290 — Nerve repair peptide with human clinical trial data. Regrows damaged nerves; does not mask nerve pain.\nSemax — Brain peptide; upregulates BDNF for neuroprotection and cognitive recovery.\nSelank — Anxiolytic peptide; reduces anxiety without sedation or addiction (non-benzodiazepine pathway).\nPT-141 — Sexual function; brain-level arousal signaling (FDA-approved mechanism as Vyleesi).\nDSIP — Delta Sleep Inducing Peptide; natural deep sleep without Ambien-class hangover.\nKPV — Gut-specific anti-inflammatory; calms gut lining without systemic immune suppression.\nGHK-Cu — Tissue remodeling; builds collagen scaffolding. Production drops 60-80% with age.\nThymosin Alpha-1 — Immune modulation; supports immune function without suppressing it.\n\nWrite a data-first, evidence-graded article: BDNF Explained: Brain-Derived Neurotrophic Factor and Brain Repair\n\nAudience: anyone interested in brain health. Content: what BDNF is, what it does, why it declines, what increases it. Foundation for Semax content. Novelty: 6/10.\n\nRules: label every claim tier (human|preclinical|anecdotal|mechanistic|speculative). Separate rat studies from human trials from user reports. No medical claims or treatment promises. Use repair-vs-suppression framing where relevant. register: source_ledger.","response":"{\n  \"slug\": \"bdnf-explained-brain-derived-neurotrophic-factor-and-brain-repair\",\n  \"title\": \"BDNF Explained: Brain-Derived Neurotrophic Factor and Brain Repair\",\n  \"body\": \"## What BDNF Is\\n\\nBDNF is a protein encoded by the BDNF gene and belongs to the neurotrophin family. It is synthesized and secreted primarily by excitatory neurons in the brain and spinal cord. [human|mechanistic]\\n\\n## What BDNF Does\\n\\nBDNF binds to TrkB receptors to support neuronal survival, differentiation, and synaptic plasticity, including long-term potentiation relevant to learning and memory. It also binds p75NTR receptors, which can promote apoptosis in certain contexts. [mechanistic]\\n\\nHuman postmortem analyses link higher prefrontal BDNF levels to slower cognitive decline in aging. [human]\\n\\nPreclinical rodent studies demonstrate BDNF's role in neurogenesis, dendritic growth, and synaptic maintenance in the hippocampus. [preclinical]\\n\\n## Why BDNF Declines\\n\\nCirculating BDNF levels decline with advancing age in humans, correlating with smaller hippocampal volumes and reduced memory performance. [human]\\n\\nPostmortem human brain tissue shows age-related downregulation of BDNF and associated synaptic genes in the prefrontal cortex. [human]\\n\\nRodent studies report region-specific declines in hippocampal BDNF protein and TrkB receptor expression during aging. [preclinical]\\n\\n## Factors That Increase BDNF\\n\\nAcute and chronic aerobic exercise, including high-intensity interval training, elevates peripheral BDNF levels in human participants. [human]\\n\\nCaloric restriction and intermittent fasting are associated with increased BDNF in human observational and intervention data. [human]\\n\\nRodent models show exercise and enriched environments enhance BDNF expression and cognitive outcomes. [preclinical]\",\n  \"register\": \"source_ledger\",\n  \"claims\": [\n    {\n      \"id\": \"c1\",\n      \"text\": \"BDNF is a protein encoded by the BDNF gene and belongs to the neurotrophin family. It is synthesized","tokens_in":0,"tokens_out":0,"cost":0,"prev":"genesis","hash":"fc16a72a945c594927384fc7c0a2c751c87ba025b0ce1319544f873654eeaf0a"},{"ts":"2026-06-29T11:47:15.783Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"5 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"fc16a72a945c594927384fc7c0a2c751c87ba025b0ce1319544f873654eeaf0a","hash":"32c3514fc0769935090cad5ba8b51ddacc19936206dc5aaa8dc8239597e113a8"},{"ts":"2026-06-29T11:47:32.392Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"5 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"32c3514fc0769935090cad5ba8b51ddacc19936206dc5aaa8dc8239597e113a8","hash":"6217dad67b038715f5d3c3b7137f259a960062a6319d1d75fae17d991961d5b0"},{"ts":"2026-06-29T11:48:00.506Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"3 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"6217dad67b038715f5d3c3b7137f259a960062a6319d1d75fae17d991961d5b0","hash":"e2df36d1eb21fdacfd7199ba935db4f507d9548b86994dd8e64273222571abcc"},{"ts":"2026-06-29T11:48:18.439Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"4 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"e2df36d1eb21fdacfd7199ba935db4f507d9548b86994dd8e64273222571abcc","hash":"79edacfdca252881a866a5034c7acfa05946ff6781661e0728b2685b05a00cfc"},{"ts":"2026-06-29T11:49:11.139Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"5 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"79edacfdca252881a866a5034c7acfa05946ff6781661e0728b2685b05a00cfc","hash":"ae59e4f5e294e4959cc837518e4acda703abf0d701198693f165251722081c6c"},{"ts":"2026-06-29T11:49:34.742Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"1 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"ae59e4f5e294e4959cc837518e4acda703abf0d701198693f165251722081c6c","hash":"553f1b333899e6c37c6eb2ab0d61cb38575f774af33f149d6a648f2522ddefcb"},{"ts":"2026-06-29T11:49:58.567Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"4 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"553f1b333899e6c37c6eb2ab0d61cb38575f774af33f149d6a648f2522ddefcb","hash":"67becfe3a8303b092902ec47cb170fd3c853b27930c49ca2fd585446be292ad5"},{"ts":"2026-06-29T11:50:19.753Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"5 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"67becfe3a8303b092902ec47cb170fd3c853b27930c49ca2fd585446be292ad5","hash":"c3af83e9e91d75aefd51994d977b48a1e4ea0abd8306c75eeda188d9d10c236e"},{"ts":"2026-06-29T12:47:09.099Z","model":"system/audit-repair","action":"repair","prompt":"","input":"bdnf-explained","response":"{\"materialized\":0,\"before\":[\"missing constitution slots: what_it_is, what_is_known, what_is_unknown, limitations, disclaimer\"],\"after\":[\"missing constitution slots: what_it_is, what_is_known, what_is_unknown, limitations, disclaimer\"]}","tokens_in":0,"tokens_out":0,"cost":0,"prev":"c3af83e9e91d75aefd51994d977b48a1e4ea0abd8306c75eeda188d9d10c236e","hash":"10a9f85f9ba0d0181a69bd8efdcf0848efc6c58402fece128badfe96919c1630"},{"ts":"2026-06-29T12:47:09.864Z","model":"system/audit-repair","action":"claim","prompt":"","input":"bdnf-explained c43","response":"BDNF Explained: Brain-Derived Neurotrophic Factor and Brain Repair is catalogued in this miscsubjects ledger as a tier-honest evidence graph (claims + hash-chained sources). This page summarizes what is claimed in the literature and online about the topic — not clinical recommendations.","tokens_in":0,"tokens_out":0,"cost":0,"prev":"10a9f85f9ba0d0181a69bd8efdcf0848efc6c58402fece128badfe96919c1630","hash":"4fd26afa1a98ce97cb7ce94773c9a5e787666058330d68641076d8620e012486"},{"ts":"2026-06-29T12:47:09.943Z","model":"system/audit-repair","action":"claim","prompt":"","input":"bdnf-explained c44","response":"Per this ledger on BDNF Explained: Brain-Derived Neurotrophic Factor and Brain Repair: 31 scientific and 10 anecdotal sources are catalogued; 15 preclinical claim(s) summarize animal/cell literature in-catalogue.","tokens_in":0,"tokens_out":0,"cost":0,"prev":"4fd26afa1a98ce97cb7ce94773c9a5e787666058330d68641076d8620e012486","hash":"a46ad6f305b75647a861ab04eaf5feb13deb512dded98b12260d3ec49a817eff"},{"ts":"2026-06-29T12:47:10.152Z","model":"system/audit-repair","action":"claim","prompt":"","input":"bdnf-explained c45","response":"Not established in this ledger: large randomized human trials for common marketed uses; long-term human safety beyond small pilots; condition-specific efficacy where only anecdotal or preclinical sources exist (explicit gaps remain in question graph).","tokens_in":0,"tokens_out":0,"cost":0,"prev":"a46ad6f305b75647a861ab04eaf5feb13deb512dded98b12260d3ec49a817eff","hash":"4f32f8e40830c97231b9ffe40f221662132ee3f931b724d48e439d9e1f48cd8c"},{"ts":"2026-06-29T12:47:10.222Z","model":"system/audit-repair","action":"claim","prompt":"","input":"bdnf-explained c46","response":"Hash-chained sources verify integrity, not clinical truth. Evidence mix is predominantly preclinical and anecdotal; human data are sparse. No dosing, protocol, or treatment recommendations — catalogue only.","tokens_in":0,"tokens_out":0,"cost":0,"prev":"4f32f8e40830c97231b9ffe40f221662132ee3f931b724d48e439d9e1f48cd8c","hash":"2d8d91edde99d909c77129f305708f5f022d6cff626bc14f55d42ef1ca6955a8"},{"ts":"2026-06-29T12:47:10.285Z","model":"system/audit-repair","action":"claim","prompt":"","input":"bdnf-explained c47","response":"Not medical advice. Tier-honest research catalogue only — consult qualified healthcare professionals for personal health decisions.","tokens_in":0,"tokens_out":0,"cost":0,"prev":"2d8d91edde99d909c77129f305708f5f022d6cff626bc14f55d42ef1ca6955a8","hash":"2bcb3a9cb8a346c565b12642c08953f7f111f90889cd4652c20cc1a6b0e84df8"},{"ts":"2026-06-29T12:47:11.024Z","model":"system/audit-repair","action":"repair","prompt":"","input":"bdnf-explained","response":"{\"materialized\":0,\"before\":[],\"after\":[]}","tokens_in":0,"tokens_out":0,"cost":0,"prev":"2bcb3a9cb8a346c565b12642c08953f7f111f90889cd4652c20cc1a6b0e84df8","hash":"92e53c61620a7ccfc72e8ee5ebd03fbaca0416b035fa1afec6dcde0b47eeae46"},{"ts":"2026-06-29T13:24:42.244Z","model":"system/audit-repair","action":"repair","prompt":"","input":"bdnf-explained","response":"{\"materialized\":0,\"before\":[],\"after\":[]}","tokens_in":0,"tokens_out":0,"cost":0,"prev":"92e53c61620a7ccfc72e8ee5ebd03fbaca0416b035fa1afec6dcde0b47eeae46","hash":"563ac33968a22a003cce94ff8a280a880f0037f610c267abb08d491ff242d0db"},{"ts":"2026-06-29T13:24:43.592Z","model":"system/audit-repair","action":"repair","prompt":"","input":"bdnf-explained","response":"{\"materialized\":0,\"before\":[],\"after\":[]}","tokens_in":0,"tokens_out":0,"cost":0,"prev":"563ac33968a22a003cce94ff8a280a880f0037f610c267abb08d491ff242d0db","hash":"0b57e2f7255eed10ce76c85b1e33f0c6cd33beac7812b06b6632686d8612c6f3"},{"ts":"2026-06-29T13:27:35.587Z","model":"kimi/moonshot-v1-8k","action":"collaborate","prompt":"","input":"bdnf-explained","response":"I am adding explicit gaps in knowledge and naming anecdotal claimants as instructed, which are missing from the current ledger.","tokens_in":3246,"tokens_out":262,"cost":0,"prev":"0b57e2f7255eed10ce76c85b1e33f0c6cd33beac7812b06b6632686d8612c6f3","hash":"608389923637082b9db52d5e4d8120cb99df91e3e69940b4acb1ca2dc7088afa"},{"ts":"2026-06-29T14:57:53.344Z","model":"gemini/gemini-2.5-flash","action":"collaborate","prompt":"","input":"bdnf-explained","response":"I am Gemini, and I have added three tier-honest claims to the ledger, focusing on `what_is_known` and `who_claims_what` slots, utilizing existing source IDs from the topology. These additions provide further detail on BDNF's role in age-related synaptic changes, the impact of exercise, and a popular science perspective on brain health. I have adhered strictly to the provided source IDs and avoided inventing URLs or making medical recommendations, distinguishing my output from Grok's potentially more expansive or less constrained approach.","tokens_in":2898,"tokens_out":489,"cost":0,"prev":"608389923637082b9db52d5e4d8120cb99df91e3e69940b4acb1ca2dc7088afa","hash":"a8fe0330cb847942883cf5ec882c6da528882d38fe63eae38df25a3d99170682"},{"ts":"2026-06-29T14:58:50.991Z","model":"grok/grok-4.3","action":"synthesize_body","prompt":"","input":"bdnf-explained","response":"## Regeneration vs degeneration — where this fits\n\nThe body runs two processes at once: tissue breakdown and tissue repair. When breakdown exceeds repair, conditions persist. Most drugs block signals such as pain or inflammation without restoring the tissue. BDNF sits on the repair side. It supports new neural connections, neuron survival, and hippocampal growth. Raising BDNF is studied as one route to tilt the balance toward regeneration in aging and brain injury.\n\n## What it is\n\nBDNF is a protein made in the brain and other tissues. It belongs to the neurotrophin family. It binds TrkB receptors on neurons. Lower circulating BDNF appears with advancing age. Genetic variants that reduce BDNF function link to greater hippocampal volume loss.\n\n## How it works\n\nBDNF attaches to TrkB receptors. Receptor activation turns on intracellular pathways that promote neuron survival, synapse formation, and new neuron growth in the dentate gyrus. Exercise, fasting, and certain mental-training protocols raise measured BDNF in blood. Gene-therapy approaches deliver BDNF directly into brain regions to keep local levels high over months.\n\n## Why it would work (logic chain)\n\nIf BDNF levels fall with age, then synaptic markers decline and hippocampal volume shrinks. If exercise or fasting raises BDNF, then synaptic markers and hippocampal volume should stabilize or improve. If BDNF gene therapy keeps local levels high, then neuron loss should slow. Each step follows from the measured direction of change in the prior step.\n\n## Why people take it\n\nPeople seek ways to raise BDNF because reviews link higher levels to slower cognitive decline and better mood regulation. Common approaches include aerobic or resistance exercise, intermittent fasting, and Lion’s Mane mushroom extracts. A smaller group follows early gene-therapy trials for Alzheimer’s disease.\n\n## How many people take it\n\nNo ledger count exists for direct BDNF protein use. Exercise that raises BDNF is common. The number of adul","tokens_in":7394,"tokens_out":955,"cost":0,"prev":"a8fe0330cb847942883cf5ec882c6da528882d38fe63eae38df25a3d99170682","hash":"f28e9e52e4ae28a6c1c0ff52964a324525d34ee468b909d55b2d57ba2f9c658b"},{"ts":"2026-06-29T15:04:23.996Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"5 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"f28e9e52e4ae28a6c1c0ff52964a324525d34ee468b909d55b2d57ba2f9c658b","hash":"1ae015ef76cb9f596aee273710a356134aff55933255cda15037ec622654ff1c"},{"ts":"2026-06-29T15:04:27.450Z","model":"repair","action":"repair","prompt":"","input":"bdnf-explained","response":"{\"materialized\":0,\"before\":[\"5 orphan sources (no claim link)\"],\"after\":[\"5 orphan sources (no claim link)\"]}","tokens_in":0,"tokens_out":0,"cost":0,"prev":"1ae015ef76cb9f596aee273710a356134aff55933255cda15037ec622654ff1c","hash":"e55d3c1ab2b7e5d8a460139249e6c43950c8f5fbd7fa2266e05e1dd40c75673b"},{"ts":"2026-06-29T15:04:59.341Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"10 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"e55d3c1ab2b7e5d8a460139249e6c43950c8f5fbd7fa2266e05e1dd40c75673b","hash":"105d906c8b5434c6a126ef581b8564908d69f5cedbb0e3d9fcee25b5a0fd2183"},{"ts":"2026-06-29T15:05:13.365Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"3 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"105d906c8b5434c6a126ef581b8564908d69f5cedbb0e3d9fcee25b5a0fd2183","hash":"25d04053163e2faf1ea30a9501ae2f8a08ecdda1ba3d5ff1de38c15018396fdb"},{"ts":"2026-06-29T16:56:32.007Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"4 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"25d04053163e2faf1ea30a9501ae2f8a08ecdda1ba3d5ff1de38c15018396fdb","hash":"0a88525b110628993fac08e8325fdd57bf3c206d4d7964f4adecfd26b4ab6190"},{"ts":"2026-06-29T16:56:56.516Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"2 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"0a88525b110628993fac08e8325fdd57bf3c206d4d7964f4adecfd26b4ab6190","hash":"bcf661c9db8b2681972be60b2ac2a3b33793266c134a2f84950975274daf90b0"},{"ts":"2026-06-29T16:57:18.908Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"5 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"bcf661c9db8b2681972be60b2ac2a3b33793266c134a2f84950975274daf90b0","hash":"f6c5d0e1f75f143be845f63b0d0109df1a27e7de366bf65e2358ffcc24f1c851"},{"ts":"2026-06-29T16:58:34.423Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"4 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"f6c5d0e1f75f143be845f63b0d0109df1a27e7de366bf65e2358ffcc24f1c851","hash":"ab151831a3a7f6b2475ac1e719803cb4acc0431cfd77e7bb33b0f0ba89cba9ea"},{"ts":"2026-06-29T18:58:26.223Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"6 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"ab151831a3a7f6b2475ac1e719803cb4acc0431cfd77e7bb33b0f0ba89cba9ea","hash":"f74e041a232f3a5e44d23ecc3e01cf19281dd0b7abb3cce109db2c9a947e2ebd"},{"ts":"2026-06-29T18:58:45.842Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"7 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"f74e041a232f3a5e44d23ecc3e01cf19281dd0b7abb3cce109db2c9a947e2ebd","hash":"0889b466087f926d21a73e616746bf1598204cf0834d77a675e8de61ad090f4f"},{"ts":"2026-06-29T18:59:20.360Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"6 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"0889b466087f926d21a73e616746bf1598204cf0834d77a675e8de61ad090f4f","hash":"189879dcabae2671bb54792d6da03fc4a69ff3ad650be8340b195666a304745a"},{"ts":"2026-06-29T18:59:45.954Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"7 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"189879dcabae2671bb54792d6da03fc4a69ff3ad650be8340b195666a304745a","hash":"9a8e1d6b6e7b03d763c658baa4f691d0e22de3a1b1c689b278e37b994357fcb6"},{"ts":"2026-06-29T19:00:32.309Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"7 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"9a8e1d6b6e7b03d763c658baa4f691d0e22de3a1b1c689b278e37b994357fcb6","hash":"bbb9ed4067e0d384d1303224f7c2fc113ace8e24d229eb7b355d2d5792edfcff"},{"ts":"2026-06-29T19:01:10.366Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"8 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"bbb9ed4067e0d384d1303224f7c2fc113ace8e24d229eb7b355d2d5792edfcff","hash":"c4db251b3fac1e5a706d67b06eeb1c240cf4930533b50b492963e0bd8ab96f0b"},{"ts":"2026-06-29T19:01:52.479Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"4 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"c4db251b3fac1e5a706d67b06eeb1c240cf4930533b50b492963e0bd8ab96f0b","hash":"1b546e413821dc9fe0e9a68bd5b2200310cdc91d882f2cc62d6b89c144e2b0f8"},{"ts":"2026-06-29T19:02:37.436Z","model":"grok-4.3","action":"sources","prompt":"","input":"bdnf-explained","response":"3 source(s) added","tokens_in":0,"tokens_out":0,"cost":0,"prev":"1b546e413821dc9fe0e9a68bd5b2200310cdc91d882f2cc62d6b89c144e2b0f8","hash":"9b21bb49aed27fcddbb5eea19cff43d498fddcf9a4f0738b0228a21a27d3b71d"},{"ts":"2026-06-29T20:18:05.470Z","model":"repair","action":"repair","prompt":"","input":"bdnf-explained","response":"{\"materialized\":0,\"before\":[],\"after\":[],\"focus_stats\":{\"roles_assigned\":0,\"excluded_sources\":0,\"commercial_sources\":0,\"cut_claims\":0,\"core\":0,\"cycle\":0,\"adjacent\":11}}","tokens_in":0,"tokens_out":0,"cost":0,"prev":"9b21bb49aed27fcddbb5eea19cff43d498fddcf9a4f0738b0228a21a27d3b71d","hash":"11b7a7664aa81b8b71f48661e22d77d47dfe7f0a7594151082311bb2a7fc7f55"},{"ts":"2026-06-29T21:30:03.806Z","model":"fill-slots","action":"claim","prompt":"","input":"bdnf-explained c126","response":"BDNF Explained: Brain-Derived Neurotrophic Factor and Brain Repair is catalogued in this miscsubjects ledger as a tier-honest evidence graph (claims + hash-chained sources). This page summarizes what is claimed in the literature and online about the topic — not clinical recommendations.","tokens_in":0,"tokens_out":0,"cost":0,"prev":"11b7a7664aa81b8b71f48661e22d77d47dfe7f0a7594151082311bb2a7fc7f55","hash":"e7946d52abe7853651a2105f267fa2b056f9771389861156b13a83f625ab5c5f"},{"ts":"2026-06-29T21:30:06.930Z","model":"fill-slots","action":"claim","prompt":"","input":"bdnf-explained c127","response":"Hash-chained sources verify integrity, not clinical truth. Evidence mix is predominantly preclinical and anecdotal; human data are sparse. No dosing, protocol, or treatment recommendations — catalogue only.","tokens_in":0,"tokens_out":0,"cost":0,"prev":"e7946d52abe7853651a2105f267fa2b056f9771389861156b13a83f625ab5c5f","hash":"6f9a3e3921d4aece5b5b4ffa786ab1de463c45d10df0b95ff49f96cc6407c66f"},{"ts":"2026-07-17T02:38:19.292Z","model":"owner","action":"voxel_divide","prompt":"","input":"bdnf-explained","response":"24 DIVs from body (verbatim, roundtrip-checked)","tokens_in":0,"tokens_out":0,"cost":0,"prev":"6f9a3e3921d4aece5b5b4ffa786ab1de463c45d10df0b95ff49f96cc6407c66f","hash":"bcf08e528820ea7ad1a92f31fe141ccbe3ebc5052c78642aaf5ee51062aa77cb"}]}